Dergiler / Diagnostic and Interventional Radiology / 2016 / Cilt: 22 - Sayı: 1

The role of multidetector CT in local staging and evaluation of retroperitoneal surgical margin involvement in colon cancer

Sayfa
5–12
DOI
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Interob-server agreement was moderate (?=0.518).CONCLUSIONMDCT is a promising technique with moderate interobserver agreement in detection of extra-mural invasion, lymph node metastases, and RSM involvement in colon carcinomas.

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Amaç & Hipotez:PURPOSE We aimed to evaluate preoperative T and N staging and retroperitoneal surgical margin (RSM) involvement in colon cancer using multidetector computed tomography (MDCT).METHODSIn this retrospective study, preoperative MDCTs of 141 patients with colon adenocarcinoma were evaluated in terms of T and N staging and retroperitoneal surgical margin involvement by two observers.
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Temel Bulgular & Veri:Results were compared with histopathology.RESULTSIn determining extramural invasion, sensitivity, specificity, positive predictive value (PPV), neg-ative predictive value (NPV), and accuracy of MDCT were 81%, 50%, 95%, 26%, and 81% for ob-server 1 and 87%, 75%, 97%, 27%, and 84% for observer 2, respectively.
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Sonuç & Katkı:Interob-server agreement was moderate (?=0.518).CONCLUSIONMDCT is a promising technique with moderate interobserver agreement in detection of extra-mural invasion, lymph node metastases, and RSM involvement in colon carcinomas.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Abstract

PURPOSE We aimed to evaluate preoperative T and N staging and retroperitoneal surgical margin (RSM) involvement in colon cancer using multidetector computed tomography (MDCT).METHODSIn this retrospective study, preoperative MDCTs of 141 patients with colon adenocarcinoma were evaluated in terms of T and N staging and retroperitoneal surgical margin involvement by two observers. Results were compared with histopathology.RESULTSIn determining extramural invasion, sensitivity, specificity, positive predictive value (PPV), neg-ative predictive value (NPV), and accuracy of MDCT were 81%, 50%, 95%, 26%, and 81% for ob-server 1 and 87%, 75%, 97%, 27%, and 84% for observer 2, respectively. Moderate interobserver agreement was observed (?=0.425). In determining T stage of the tumor, accuracy of MDCT was 55% for observer 1 and 51% for observer 2. In the detection of lymph node metastasis, sensitivity, specificity, PPV, NPV, and accuracy of MDCT were 84%, 46%, 60%, 74% and 64% for observer 1 and 84%, 56%, 65%, 78%, and 70% for observer 2, respectively. Interobserver agree-ment was substantial (?=0.650). RSM was involved in six cases (4.7%). When only retroperitoneal colon segments were considered, 1.6% of subjects demonstrated RSM involvement. Four of the six RSM-positive tumors were located on sigmoid colon and one tumor was on transverse colon and caecum. Considering all colon tumors, in the detection of RSM involvement, sensitivity and specificity of MDCT were 33% and 81% for observer 1 and 50% and 80% for observer 2. Interob-server agreement was moderate (?=0.518).CONCLUSIONMDCT is a promising technique with moderate interobserver agreement in detection of extra-mural invasion, lymph node metastases, and RSM involvement in colon carcinomas.

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Bu Makaleye Atıf Yap

ELİBOL, F. D., OBUZ, F., SÖKMEN, S., TERZİ, C., CANDA, A. E., SAĞOL, Ö., SARIOĞLU, S. (2016). The role of multidetector CT in local staging and evaluation of retroperitoneal surgical margin involvement in colon cancer. Diagnostic and Interventional Radiology, Cilt: 22 - Sayı: 1, 5–12. https://ajindex.com/articles/203576

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  1. Smith NJ, Bees N, Barbachano Y, Norman AR, Swift RI, Brown G. Preoperative computed tomography staging of nonmetastatic colon cancer predicts outcome: implications for clinical trials. Brit J Can- cer 2007; 96:1030-1036. [CrossRef] Tudyka V, Blomqvist L, Beets-Tan RGH, et al. EU- RECCA consensus conference highlights about colon & rectal cancer multidisciplinary man- agement: the radiology experts review. Eur J Surg Oncol 2014; 40:469-475. [CrossRef] Merkel S, Wein A, Gunther K, Papadopoulos T, Hohenberger W, Hermanek P. High-risk groups of patients with Stage II colon carcinoma. Can- cer 2001; 92:1435-1443. [CrossRef] Dighe S, Purkayastha S, Swift I, et al. Diagnostic precision of CT in local staging of colon cancers: a meta-analysis. Clin Radiol 2010; 65:708-719. [CrossRef] Dighe S, Blake H, Koh MD, et al. Accuracy of multidetector computed tomography in iden- tifying poor prognostic factors in colonic can- cer. Br J Surg 2010; 97:1407-1415. [CrossRef] Bateman AC, Carr NJ, Warren BF. The retroperito- neal surface in distal caecal and proximal ascend- ing colon carcinoma: the Cinderella surgical mar- gin? J Clin Pathol 2005; 58:426-428. [CrossRef] Quirke P, Williams GT, Ectors N, Ensari A, Piard F, Nagtegaal I. The future of the TNM staging system in colorectal cancer: time for a debate? Lancet Oncol 2007; 8:651-657. [CrossRef] Foxtrot Collaborative v. Feasibility of preop- erative chemotherapy for locally advanced, operable colon cancer: the pilot phase of a ran- domised controlled trial. Lancet Oncol 2012; 13:1152-1160. [CrossRef] Gunderson LL, Jessup JM, Sargent DJ, Greene FL, Stewart AK. Revised TN categorization for colon cancer based on national survival outcomes data. J Clin Oncol 2010; 28:264-271. [CrossRef] Quirke P, Williams GT. Standards and minimum datasets for reporting common cancer. Mini- mum dataset for colorectal carcinoma histo- pathology reports. London: Royal College of Pathologists, 1998.
  2. Burton S, Brown G, Bees N, et al. Accuracy of CT prediction of poor prognostic features in colonic cancer. Brit J Radiol 2008; 81:10-19. [CrossRef] Sibileau E, Ridereau-Zins C, Vanel D, et al. Accu- racy of water-enema multidetector computed tomography (WE-MDCT) in colon cancer stag- ing: a prospective study. Abdom Imaging 2014; 39:941-948. [CrossRef] Venara A, Ridereau-Zins C, Toque L, et al. Wa- ter-enema multidetector computed tomogra- phy for planning surgery. Int J Colorectal Dis 2015; 1-6. [CrossRef] Leufkens AM, van den Bosch MA, van Leeuwen