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Dergiler / International Journal of Medical Biochemistry / 2020 / Cilt: 3 - Sayı: 3

The effects of chlorhexidine-based preservative tubes on routine urinalysis stability

İnanç KARAKOYUN
Fatma Demet ARSLAN
Anıl BAYSOY
Murat AKŞİT
Ayfer ÇOLAK
Banu ISBİLEN BASOK
Sayfa
155–160
DOI
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Conclusion: Although storage in chlorhexidine-based preservative tubes has limited effects on chemical strip analysis, these tubes may not be considered optimal for microscopic examination.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objectives: To evaluate the effects of chlorhexidine-based preservative tubes on analytes for routine urinalysis.
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Temel Bulgular & Veri:Methods: Urine specimen (n=84) aliquots in polystyrene tubes (PS) with no additives (Fıratmed Co.
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Sonuç & Katkı:Conclusion: Although storage in chlorhexidine-based preservative tubes has limited effects on chemical strip analysis, these tubes may not be considered optimal for microscopic examination.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objectives: To evaluate the effects of chlorhexidine-based preservative tubes on analytes for routine urinalysis. Methods: Urine specimen (n=84) aliquots in polystyrene tubes (PS) with no additives (Fıratmed Co. Ltd., Istanbul, Turkey) and in Becton–Dickinson Vacutainer® Plus Urinalysis Preservative (BD-UAP) tubes (Becton Dickinson Inc., NJ, USA) were analyzed on automatic modular urine analyzer (Dirui Industry, Changchun, China) and the results were compared. Stability was assessed by re-analyzing urine samples in BD-UAP tubes after three and six hours of storage and comparing with initial results. Cohen’s kappa coefficient (κ) was calculated to assess the agreement of results. Results: Squamous epithelial cell and pH agreement between the tubes was moderate (κ=0.60 and 0.58, respectively). Bilirubin, ketone, protein, nitrite, and glucose showed perfect agreement with the PS tube and remained stable for up to six hours in the BD-UAP tube (κ=1.00, 0.92, 0.83, 0.93, 1.00, respectively). Red blood cells, white blood cells, bacteria, blood, and leukocyte esterase showed moderate to substantial stability at six hours (κ=0.56, 0.77, 0.76, 0.87, 0.57, respectively). Conclusion: Although storage in chlorhexidine-based preservative tubes has limited effects on chemical strip analysis, these tubes may not be considered optimal for microscopic examination.

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Bu Makaleye Atıf Yap

KARAKOYUN, İ., ARSLAN, F. D., BAYSOY, A., AKŞİT, M., ÇOLAK, A., BASOK, B. I. (2020). The effects of chlorhexidine-based preservative tubes on routine urinalysis stability. International Journal of Medical Biochemistry, Cilt: 3 - Sayı: 3, 155–160. https://ajindex.com/articles/200284

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