KaydedilenlerDerginizi ekleyin

Dergiler / Kocaeli Tıp Dergisi / 2019 / Cilt: 8 - Sayı: 3

Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?

Ortalama Trombosit Hacmi/Lenfosit Sayısı Oranı İrritabl Barsak Sebdromu ve Subtibleri ile İlişkili midir ?

TUBA TASLAMACIOĞLU DUMAN
Burçin Meryem ATAK TEL
Sayfa
50–54
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In conclusion, despite increased MPVLR could not differentiate IBS constipation predominance from the IBS diarrhea predominance, it could be useful in establishing the diagnosis of IBS.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:INTRODUCTION: Hemogram parameters are considered as inflammatory markers in various diseases.
📊
Temel Bulgular & Veri:RESULTS: The MPVLR of IBS-C, IBS-D and control groups were 0.005 (0.001), 0.004 (0.001) and 0.003 (0.001), respectively (p<0.001).
💡
Sonuç & Katkı:In conclusion, despite increased MPVLR could not differentiate IBS constipation predominance from the IBS diarrhea predominance, it could be useful in establishing the diagnosis of IBS.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

INTRODUCTION: Hemogram parameters are considered as inflammatory markers in various diseases. The objective of this study was to assess mean platelet volume to lymphocyte ratio (MPVLR) of subjects with IBS and to compare to those in healthy population. METHODS: Patients with IBS whose admissions to our outpatient internal medicine clinic were enrolled to the study. Patients with IBS were divided into two groups according to the predominant symptom, either IBS diarrhea predominant (IBS-D) or IBS constipation predominant (IBS-C). Healthy volunteers were enrolled as control group. General characteristics and MPVLR levels of the groups compared. RESULTS: The MPVLR of IBS-C, IBS-D and control groups were 0.005 (0.001), 0.004 (0.001) and 0.003 (0.001), respectively (p<0.001). Post Hoc test revealed that MPVLR of IBS-C and IBS-D groups were similar (p=0.44) and MPVLR of control groups was significantly lower than that of the IBS-C (p<0.001) and IBS-D (p<0.001) groups. DISCUSSION and CONCLUSION: The main outcome of present study was that MPVLR could be used as a marker of IBS. However, it is not useful in differentiating IBS constipation predominance from IBS diarrhea predominance. In conclusion, despite increased MPVLR could not differentiate IBS constipation predominance from the IBS diarrhea predominance, it could be useful in establishing the diagnosis of IBS.

Abstract

GİRİŞ ve AMAÇ: Hemogram parametreleri birçok çalışmada inflamatuvar belirteç olarak kullanılmaktadır. Bu çalışmamızdaki amacımız İBS ve sağlıklı kontrollerdeki ortalama trombosit hacmi/lenfosit oranının (MPVLR) karşılaştırılmasıdır. YÖNTEM ve GEREÇLER: İç hastalıkları polikliniğimize başvuran İBS’li hastalar çalışmamıza alındı. İBS’li hastalar diyare predominat İBS (IBS-D) ve konstipasyon predominant İBS (IBS-C) olarak iki ana gruba ayrıldı. Sağlıklı kişilerden de kontrol grubu oluşturuldu. Çalışmamızda grupların genel özellikleri ve MPVLR seviyeleri karşılaştırıldı. BULGULAR: IBS-C, IBS-D ve kontrol gruplardaki MPVLR sırasıyla; 0.005 (0.001), 0.004 (0.001) ve 0.003 (0.001), (p<0.001) idi. Post Hoc testi ile IBS-C ve IBS-D gruplarındaki MPVLR oranları benzer olup (p=0.44), MPVLR control grupta ise IBS-C (p<0.001) ve IBS-D (p<0.001) gruplarından anlamlı olarak düşük saptandı. TARTIŞMA ve SONUÇ: MPVLR, İBS hastalarında inflamatuvar marker olarak kullanılabileceği bu çalışmamızdaki ana sonucumuzdur. Ancak İBS grupları arasında anlamlı fark saptanmamıştır. Sonuçta İBS-C ve İBS-D arasında MPVLR benzer olmakla birlikte İBS hastalarının sağlıklılardan ayrımında kullanılabilir.

🔖

Bu Makaleye Atıf Yap

DUMAN, T. T., TEL, B. M. A. (2019). Does Mean Platelet Volume to Lymphocyte Ratio Associates with Irritable Bowel Syndrome and Its Subtypes?. Kocaeli Tıp Dergisi, Cilt: 8 - Sayı: 3, 50–54. https://ajindex.com/articles/200050

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (15)

  1. Mearin F, Lacy BE, Chang L, Chey WD, Lembo AJ, Simren M, et al. Bowel Disorders. Gastroenterology. 2016
  2. Camilleri M, Katzka DA. Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Genetic epidemiology and pharmacogenetics in irritable bowel syndrome. American journal of physiology Gastrointest Liver Physiol. 2012;302(10):G1075-84
  3. Park Y, Schoene N, Harris W. Mean platelet volume as an indicator of platelet activation: methodological issues. Platelets. 2002;13(5- 6):301-6
  4. Gasparyan AY, Stavropoulos-Kalinoglou A, Toms TE, Douglas KM, Kitas GD. Association of mean platelet volume with hypertension in rheumatoid arthritis. Inflam Allergy Drug Targets. 2010;9(1):45-50
  5. Aktas G, Kocak MZ, Duman TT, Erkus E, Atak BM, Sit M, et al. Mean Platelet Volume (MPV) as an inflammatory marker in type 2 diabetes mellitus and obesity. Bali Med J. 2018;7(3):650-3
  6. Karagoz I, Aktas G, Yoldas H, Yildiz I, Ogun MN, Bilgi M, et al. Association Between Hemogram Parameters and Survival of Critically Ill Patients. J Intensive Care Med. 2019;34(6):511-3
  7. Ha S-I, Choi D-H, Ki Y-J, Yang J-S, Park G, Chung J-W, et al. Stroke prediction using mean platelet volume in patients with atrial fibrillation. Platelets. 2011;22(6):408-14
  8. Dagistan Y, Dagistan E, Gezici AR, Halicioglu S, Akar S, Ozkan N, et al. Could red cell distribution width and mean platelet volume be a predictor for lumbar disc hernias? Ideggyogy Sz. 2016;69(11-12):411-4
  9. Kapsoritakis AN, Koukourakis MI, Sfiridaki A, Potamianos SP, Kosmadaki MG, Koutroubakis IE, et al. Mean platelet volume: a useful marker of inflammatory bowel disease activity. Am J Gastroenterol. 2001;96(3):776-81
  10. Cakir L, Aktas G, Enginyurt O, Cakir SA. Mean platelet volume increases in type 2 diabetes mellitus independent of HbA1c level. Acta Med Mediterranea. 2014;30(2):425-8
  11. Choi CU, Seo HS, Kim YK, Na JO, Lim HE, Kim JW, et al. Can mean platelet volume predict coronary vasospasm? Platelets. 2011;22(3):173-8
  12. Aktas G, Cakiroglu B, Sit M, Uyeturk U, Alcelik A, Savli H, et al. Mean platelet volume: a simple indicator of chronic prostatitis. Acta Med Mediterranea. 2013;29:551-4
  13. Sit M, Aktaş G, Yilmaz EE, Hakyemez IN, Alçelik A, Küçükbayrak A. Platelet parameters in hepatic hydatid cysts. Int J Inflam. 2013;2013
  14. Erkus E, Aktas G, Atak BM, Kocak MZ, Duman TT, Savli H. Haemogram Parameters in Vitamin D Deficiency. J Coll Physicians Surg Pak. 2018;28(10):779-82
  15. Sincer I, Gunes Y, Mansir