Dergiler / Kocaeli Tıp Dergisi / 2019 / Cilt: 8 - Sayı: 2

Clinical and Demographic Profile of Patients with Active Epilepsy: Experience From a Tertiary Care Hospital in Turkey

Aktif Epilepsili Hastaların Klinik ve Demografik Profili: Türkiye'deki Bir Üçüncü Basamak Hastanesinin Deneyimleri

Sayfa
142–149
DOI
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We believe that detailed examination with regular follow- up in comprehensive epilepsy clinics would provide a potential benefit in preventing seizures and better outcome

📌 3 Maddede Bu Makale

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Amaç & Hipotez:ABSTRACT INTRODUCTION: To investigate the clinical and demographic findings of patients at epilepsy outpatient clinic of a tertiary care hospital.
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Temel Bulgular & Veri:METHODS: We retrospectively analysed one hundred and eighty-seven patients with active epilepsy who admitted to our epilepsy clinic between January 2016 and February 2018.
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Sonuç & Katkı:We believe that detailed examination with regular follow- up in comprehensive epilepsy clinics would provide a potential benefit in preventing seizures and better outcome
🔬Tür:Araştırma Makalesi
📍Kapsam:2016 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

ABSTRACT INTRODUCTION: To investigate the clinical and demographic findings of patients at epilepsy outpatient clinic of a tertiary care hospital. METHODS: We retrospectively analysed one hundred and eighty-seven patients with active epilepsy who admitted to our epilepsy clinic between January 2016 and February 2018. In addition to demographic characteristics, we evaluated clinical variables such as; seizure frequency, duration of illness, type of seizures, antiepileptics, electroencephalographic (EEG) and magnetic resonance imaging (MRI) findings. RESULTS: The mean age of the patients were 36,9 ± 13,1 years; and 54.5% were male. Family history of epilepsy was found in 48 patients (25.7%), and 35 patients (18.7%) had a kinship between parents. The most frequent risk factors were head trauma, febrile convulsions and perinatal problems. Partial seizures was seen in 67.9 %, generalised seizures in 29.3% and unclassified seizures in 2.7%. Brain MRI of 107 patients (57.2%) and interictal EEG of 57 patients (30.5%) was normal. A total of 116 (62%) received monotherapy, while 71 (38%) continued on polytherapy. DISCUSSION AND CONCLUSION: In this study, clinical and demographic data of the patients were consistent with the literature. We believe that detailed examination with regular follow- up in comprehensive epilepsy clinics would provide a potential benefit in preventing seizures and better outcome

Abstract

ÖZ GİRİŞ ve AMAÇ: Üçüncü basamak bir hastanede epilepsi polikliniğine başvuran hastaların klinik ve demografik bulgularını araştırmak. YÖNTEM ve GEREÇLER: Ocak 2016 - Şubat 2018 tarihleri arasında epilepsi polikliniğine başvuran aktif epilepsili 187 hasta retrospektif olarak incelendi. Demografik özelliklerin yanı sıra; nöbet sıklığı, hastalık süresi, nöbet tipi, antiepileptikler, elektroensefalografik (EEG) ve manyetik rezonans görüntüleme (MRG) bulguları kaydedildi. BULGULAR: Hastaların yaş ortalaması 36,9 ± 13,1; ve % 54,5'i erkekti. Ailede epilepsi öyküsü 48 hastada (% 25.7) bulundu. 35 hastada (% 18.7) ebeveynler arasında akrabalık vardı. En sık görülen risk faktörleri kafa travması, febril konvülsiyon ve perinatal problemler idi. Fokal nöbetler % 67.9, jeneralize nöbetler% 29.3, sınıflandırılamayan nöbetler% 2.7 idi. 107 hastanın (% 57.2) beyin MR'ı ve 57 hastanın (% 30.5) interiktal EEG'si normaldi. Hastaların toplam 116'sı (% 62) monoterapi alırken, 71'i (% 38) polyterapiye almaktaydı. TARTIŞMA ve SONUÇ: Bu çalışmada, hastaların klinik ve demografik verileri literatür ile uyumlu idi. Kapsamlı epilepsi kliniklerinde düzenli takip ile yapılan ayrıntılı muayenenin nöbetlerin önlenmesinde ve daha iyi sonuç alınmasında potansiyel bir fayda sağlayacağına inanıyoruz.

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Bu Makaleye Atıf Yap

BAŞARAN, Ş., ÖĞÜN, M. N. (2019). Clinical and Demographic Profile of Patients with Active Epilepsy: Experience From a Tertiary Care Hospital in Turkey. Kocaeli Tıp Dergisi, Cilt: 8 - Sayı: 2, 142–149. https://ajindex.com/articles/198719

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Kaynakça (17)

  1. Engel Jr J. Report of the ILAE classification core group. Epilepsia. 2006;47(9):1558-68
  2. Sirven JI. Epilepsy: a spectrum disorder. Cold Spring Harb Perspect Med. 2015;5(9)
  3. Fiest KM, Sauro KM, Wiebe S, Patten SB, Kwon C-S, Dykeman J, et al. Prevalence and incidence of epilepsy: a systematic review and metaanalysis of international studies. Neurology. 2017;88(3):296-303
  4. Fisher RS, Acevedo C, Arzimanoglou A, Bogacz A, Cross JH, Elger CE, et al. ILAE official report: a practical clinical definition of epilepsy. Epilepsia. 2014;55(4):475-82
  5. Harris JC. New terminology for mental retardation in DSM-5 and ICD-11. Current opinion in psychiatry. 2013;26(3):260-2
  6. Christensen J, Kjeldsen MJ, Andersen H, Friis ML, Sidenius P. Gender differences in epilepsy. Epilepsia. 2005;46(6):956-60
  7. Carlson C, Dugan P, Kirsch HE, Friedman D, Investigators E. Sex differences in seizure types and symptoms. Epilepsy Behav. 2014;41:103-8
  8. Bharucha NE, Bharucha EP, Bharucha AE, Bhise AV, Schoenberg BS. Prevalence of epilepsy in the Parsi community of Bombay. Epilepsia. 1988;29(2):111-5
  9. Banerjee PN, Filippi D, Hauser WA. The descriptive epidemiology of epilepsy—a review. Epilepsy Res. 2009;85(1):31-45
  10. Olafsson E, Hauser WA. Prevalence of epilepsy in rural Iceland: a population‐based study. Epilepsia. 1999;40(11):1529-34
  11. Forsgren L. Prospective incidence study and clinical characterization of seizures in newly referred adults. Epilepsia. 1990;31(3):292-301
  12. Akbayram S, Sari N, Akgün C, Dogan M, Tuncer O, Caksen H, et al. The frequency of consanguineous marriage in eastern Turkey. Genet Couns. 2009;20(3):207
  13. Khan H, Mohamed A, Al-Sakini Z, Zulfiquar K, Sohail A, Shaikh R. Consanguinity, family history and risk of epilepsy: A case control study. Gulf Medical Journal. 2012;1(1):4
  14. Chentouf A, Talhi R, Dahdouh A, Benbihi L, Benilha S, Oubaiche ML, et al. Consanguinity and epilepsy in Oran, Algeria: a case–control study. Epilepsy Res. 2015;111:10-7
  15. Huseyinoglu N, Ozben S, Arhan E, Palanci Y, Gunes N. Prevalence and risk factors of epilepsy among school children in eastern Turkey. Pediatr Neurol. 2012;47(1):13-8
  16. Hüseyınoglu N, Palancı Y, Günes N, Köse Özlece H. Prevalence of Epilepsy in the University Students Representing a Young Adult Population With Normal Intelligence. Epilepsi: Journal of the Turkish Epilepsi Society. 2014;20(2)
  17. Peljto AL, Barker-Cummings C, Vasoli VM, Leibson CL, Hauser WA, Buchhalter JR, et al. Familia