KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Medical Sciences / 2015 / Cilt: 45 - Sayı: 5

Why is Alzheimer's disease confused with other dementias?

DURSUN AYGÜN
İBRAHİM LEVENT GÜNGÖR
Sayfa
1010–1014
Yayın Tarihi
2015-12-04
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

As in our representative SD case, a careful clinical history, a detailed mental evaluation, and neuroimaging will overcome this difficulty in diagnosis.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Alzheimer disease (AD) is the most common cause of dementia.
📊
Temel Bulgular & Veri:The cardinal manifestation of AD is progressive loss of memory.
💡
Sonuç & Katkı:As in our representative SD case, a careful clinical history, a detailed mental evaluation, and neuroimaging will overcome this difficulty in diagnosis.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alzheimer disease · dementia · atypical presentations

Özet

Alzheimer disease (AD) is the most common cause of dementia. The cardinal manifestation of AD is progressive loss of memory. However, there are some nonamnestic presentations of AD, also called atypical AD. Symptoms of AD can sometimes start suddenly. In the presence of atypical symptoms or sudden onset, it may be difficult to distinguish AD from other dementias. We would like to discuss the confusing features of atypical AD that mimic other dementias. In this review, the literature associated with confusing features of AD, suggesting other dementia syndromes, is reviewed. In addition, a case of semantic dementia (SD) with the complaint of forgetfulness previously diagnosed as AD is presented together with clinical and radiological clues of the differential diagnosis of dementia syndromes. As in our representative SD case, a careful clinical history, a detailed mental evaluation, and neuroimaging will overcome this difficulty in diagnosis.

Abstract

Alzheimer disease (AD) is the most common cause of dementia. The cardinal manifestation of AD is progressive loss of memory. However, there are some nonamnestic presentations of AD, also called atypical AD. Symptoms of AD can sometimes start suddenly. In the presence of atypical symptoms or sudden onset, it may be difficult to distinguish AD from other dementias. We would like to discuss the confusing features of atypical AD that mimic other dementias. In this review, the literature associated with confusing features of AD, suggesting other dementia syndromes, is reviewed. In addition, a case of semantic dementia (SD) with the complaint of forgetfulness previously diagnosed as AD is presented together with clinical and radiological clues of the differential diagnosis of dementia syndromes. As in our representative SD case, a careful clinical history, a detailed mental evaluation, and neuroimaging will overcome this difficulty in diagnosis.

🔖

Bu Makaleye Atıf Yap

AYGÜN, D., GÜNGÖR, İ. L. (2015). Why is Alzheimer's disease confused with other dementias?. Turkish Journal of Medical Sciences, Cilt: 45 - Sayı: 5, 1010–1014. https://ajindex.com/articles/198427

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (8)

  1. Fratiglioni L, Winblad B, Strauss E. Prevention of Alzheimer’s disease and dementia. Major findings from the Kungsholmen Project. Physiol Behav 2007; 92: 98–104. 2. Querfurth HW, LaFerla FM. Alzheimer’s disease. N Engl J Med 2010; 362: 329–344. de Souza LC, Bertoux M, Funkiewiez A, Samri D, Azuar C, Habert MO, Kas A, Lamari F, Sarazin M, Dubois B. Frontal presentation of Alzheimer’s disease. Dement Neuropsychol 2013; 7: 66–74.
  2. Maurer K, Volk S, Gerbaldo H. Auguste D and Alzheimer’s disease. Lancet 1997; 349: 1546–1549. 5. Harciarek M, Kertesz A. Primary progressive aphasias and their contribution to the contemporary knowledge about the brain- language relationship. Neuropsychol Rev 2011; 21: 271–287.
  3. Graham A, Davies R, Xuereb J, Halliday G, Kril J, Creasey H, Graham K, Hodges J. Pathologically proven frontotemporal dementia presenting with severe amnesia. Brain 2005; 128: 597–605.
  4. La Joie R, Landeau B, Perrotin A, Bejanin A, Egret S, Pélerin A, Mézenge F, Belliard S, de La Sayette V, Eustache F et al. Intrinsic connectivity identifies the hippocampus as a main crossroad between Alzheimer’s and semantic dementia- targeted networks. Neuron 2014; 81: 1417–1428. von Gunten A, Bouras C, Kövari E, Giannakopoulos P, Hof PR. Neural substrates of cognitive and behavioral deficits in atypical Alzheimer’s disease. Brain Res Rev 2006; 51: 176–211.
  5. McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR Jr, Kawas CH, Klunk WE, Koroshetz WJ, Manly JJ, Mayeux R et al. The diagnosis of dementia due to Alzheimer’s disease: recommendations from the National Institute on Aging- Alzheimer’s Association workgroups on diagnostic guide lines for Alzheimer’s disease. Alzheimers Dement 2011; 7: 263–269.
  6. Dubois B, Feldman HH, Jacova C, Dekosky ST, Barberger- Gateau P, Cummings J, Delacourte A, Galasko D, Gauthier S, Jicha G et al. Research criteria for the diagnosis of Alzheimer’s disease: revising the NINCDS-ADRDA criteria. Lancet Neurol 2007; 6: 734–746. Blennow K, de Leon MJ, Zetterberg H. Alzheimer’s disease. Lancet 2006; 368: 387–403.
  7. Qiu C, Kivipelto M, von Strauss E. Epidemiology of Alzheimer’s disease: occurrence, determinants and strategies toward intervention. Dialogues Clin Neurosci 2009; 11: 111–128. Mendez MF. Early-onset Alzheimer’s disease: nonamnestic subtypes and type 2 AD. Arch Med Res 2012; 43: 677–685.
  8. Duker AP, Espay AJ, Wszolek ZK, Rademakers R, Dickson DW, Kelley BJ. Atypical motor and behavioral presentations of Alzheimer disease: a case-based approach. Neuro