Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightAMAÇ: Bu çalışmada şizofreni hastalarının bakım vericileriyle olan bağlanma örüntülerinin ve bakım verici duygu ifadesinin hastaların oksidatif stres düzeyleri ile ilişkisinin araştırılması amaçlanmıştır.
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Özet
AMAÇ: Bu çalışmada şizofreni hastalarının bakım vericileriyle olan bağlanma örüntülerinin ve bakım verici duygu ifadesinin hastaların oksidatif stres düzeyleri ile ilişkisinin araştırılması amaçlanmıştır.
Abstract
OBJECTIVE: This study aims to examine the relation between the oxidative stress level of schizophrenic and caregiver’s attachment patterns and expressed emotion.MATERIAL AND METHODS: Participants are 20 schizophrenic patients (who consulted to Marmara University Medical School Hospital outpatient clinic) and their mothers, 21 healthy control and their mothers. Patients were provided Adult attachment scale (AAS), Positive and Negative Syndrome Scale (PANSS) and Calgary Depression Scale for Schizophrenia (CDSS). Expressed Emotion Scale (EES), AAS, and Beck Depression Inventory (BDE) were given to caregivers of schizophrenics. AAS and BDE were given to control group; EES and AAS were given to control group caregivers. Blood and urine sample of patient group and control group were examined in terms of oxidative stress parameters.RESULTS: Results indicate that oxidized glutathione (GSSG) (0.23±0.15 vs 0.13±0.10, p=0.02), plasma lipid peroxidation (25.80 (516.00) vs 16.43 (345.00), p=0.01) and urine malondialdehyde (MDA) (1.52±1.48 vs 0.63±0.35, p=0.01) level of patients are higher than those of control group. Caregivers of the schizophrenia patients were found to have lower levels of emotional expression than caregivers of the control group (20.0±4.29 vs 23.19±4.70, p=0.03). In the study group, there was no correlation between the levels of oxidative stress and the level of emotional expression of caregivers and caregivers’ attachment styles.CONCLUSIONS: If supported by further studies and repeated with higher sample sizes, the relation between oxidative stress parameters and mothers’ attachment and expressed emotion levels in schizophrenia will contribute to the future psychotherapeutic and psychopharmacological interventions.