Dergiler / Journal of Urological Surgery / 2019 / Cilt: 6 - Sayı: 1

The Course of Renal Function After Radical Cystectomy with Ileal Conduit Diversion for Bladder Cancer

Mesane Kanserinde Radikal Sistektomi ve İleal Kondüit Diversiyon Sonrası Böbrek Fonksiyonlarının Seyri

Sayfa
21–26
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Development of urinary tract obstruction and urinary tract infection in the postoperative period were found to be significant adverse factors affecting renal function.

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Amaç & Hipotez:Objective: We evaluated the course of the renal function and potential risk factors for renal deterioration in patients who had undergone radical cystectomy with ileal conduit diversion.
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Temel Bulgular & Veri:Materials and Methods: A retrospective study evaluated 121 patients, including 114 male and 7 female who underwent radical cystectomy with ileal conduit diversion.
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Sonuç & Katkı:Development of urinary tract obstruction and urinary tract infection in the postoperative period were found to be significant adverse factors affecting renal function.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: We evaluated the course of the renal function and potential risk factors for renal deterioration in patients who had undergone radical cystectomy with ileal conduit diversion. Materials and Methods: A retrospective study evaluated 121 patients, including 114 male and 7 female who underwent radical cystectomy with ileal conduit diversion. Estimated glomerular filtration rate (eGFR) was calculated and postoperative changes in renal function were reviewed. The clinical variables influencing renal function were evaluated. Results: The median follow-up period was 35.6 months (range, 12.2 to 139.6 months). The mean eGFR was 78.37±27.58 mL/min/1.73 m2 before surgery and 90.14±29.68 mL/min/1.73 m2 at 5 years postoperatively. The comparison of preoperative eGFR and the last follow-up eGFR showed the no statistically significant difference (p=0.195). Statistical analysis showed that development of postoperative urinary tract obstruction and postoperative urinary tract infection were significant adverse factors (p=0.008, p=0.026, respectively). Conclusion: Thirty two patients (53.3 ) developed renal deterioration during the follow-up period. Development of urinary tract obstruction and urinary tract infection in the postoperative period were found to be significant adverse factors affecting renal function.

Abstract

Amaç: Bu çalışmada mesane kanseri nedeniyle radikal sistektomi ve ileal kondüit diversiyon uygulanan hastalarda böbrek fonksiyonlarındaki değişiklik ve böbrek fonksiyon kaybı için potansiyel risk faktörleri değerlendirildi. Gereç ve Yöntem: Retrospektif çalışmada radikal sistektomi ve ileal kondüit diversiyon yapılan 114 erkek ve 7 kadın, 121 hasta değerlendirildi. Tahmini glomerüler filtrasyon hızı (eGFR) hesaplandı ve postoperatif böbrek fonksiyon değişiklikleri gözden geçirildi. Böbrek fonksiyonlarını etkileyen klinik değişkenler değerlendirildi. Bulgular: Medyan izlem süresi 35,6 ay (dağılım 12,2-139,6 ay) idi. Ortalama eGFR, ameliyat öncesi 78,37±27,58 mL/dakika/1,73 m2 ve ameliyat sonrası 5. yılda 90,14±29,68 mL/dakika/1,73 m2 idi. Ameliyat öncesi eGFR ile son takipteki eGFR k arşılaştırması istatistiksel olarak anlamlı bir fark göstermedi (p=1,95). İstatistiksel analiz postoperatif üriner sistem tıkanıklığı gelişiminin ve postoperatif üriner sistem enfeksiyonunun anlamlı olumsuz faktörler olduğunu gösterdi (sırası ile p=0,008, p=0,026). Sonuç: İzlem süreci boyunca, 32 hastanın ( 53,3) böbrek fonksiyonlarında azalma görüldü. Postoperatif üriner sistem tıkanıklığının böbrek fonksiyonlarını etkileyen önemli bir olumsuz faktör olduğu bulundu.

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Bu Makaleye Atıf Yap

ÖZER, C., GÖREN, M. R., EĞİLMEZ, T., KILINÇ, F., GÜVEL, S. (2019). The Course of Renal Function After Radical Cystectomy with Ileal Conduit Diversion for Bladder Cancer. Journal of Urological Surgery, Cilt: 6 - Sayı: 1, 21–26. https://ajindex.com/articles/189968

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Kaynakça (12)

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