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Dergiler / Turkish Journal of Biology / 2011 / Cilt: 35 - Sayı: 6

Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss.

Sinem BALTACI
Hatice Efsun KOLATAN
Osman YILMAZ
Bijen KIVÇAK
Sayfa
757–762
Yayın Tarihi
2011-06-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.

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Amaç & Hipotez:Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-inflammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats.
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Temel Bulgular & Veri:In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema.
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Sonuç & Katkı:In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.
🔬Tür:Modelleme & Sayısal Simülasyon
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Key words: Anthemis aciphylla · anti-inflammatory activity · carrageenin

Özet

Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-inflammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.

Abstract

Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-inflammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.

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Bu Makaleye Atıf Yap

BALTACI, S., KOLATAN, H. E., YILMAZ, O., KIVÇAK, B. (2011). Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss.. Turkish Journal of Biology, Cilt: 35 - Sayı: 6, 757–762. https://ajindex.com/articles/182523

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Kaynakça (15)

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