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Dergiler / Eastern Journal of Medicine / 2019 / Cilt: 24 - Sayı: 1

Effect of Acetaminophen on Viability of HeLa Cells

GÖKHAN GÖRGİŞEN
İsmail Musab GÜLAÇAR
Ersoy ÖKSÜZ1
Sayfa
53–56
DOI
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Prolonged exposure of acetaminophen led to decrease in cell survival even at minimum concentrations.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Acetaminophen is a widely used analgesic to release pain and reduce fever.
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Temel Bulgular & Veri:Overdose medication could lead to serious medical conditions such as hepatotoxicity and liver failure.
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Sonuç & Katkı:Prolonged exposure of acetaminophen led to decrease in cell survival even at minimum concentrations.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Acetaminophen is a widely used analgesic to release pain and reduce fever. Overdose medication could lead to serious medical conditions such as hepatotoxicity and liver failure. In addition to its cytotoxicity effects, it has an anti-proliferative effect in human cancer cells. In this study it is aimed to determine the apoptotic effect of acetaminophen in HeLa cells. In this perspective, HeLa cells were treated with different concentrations of acetaminophen at three different exposure times. Cell viability was determined by MTT analysis. Results showed that acetaminophen inhibited viability of HeLa cells. Its cytotoxic effect depends on exposure time and concentration. Prolonged exposure of acetaminophen led to decrease in cell survival even at minimum concentrations.

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Bu Makaleye Atıf Yap

GÖRGİŞEN, G., GÜLAÇAR, İ. M., ÖKSÜZ1, E. (2019). Effect of Acetaminophen on Viability of HeLa Cells. Eastern Journal of Medicine, Cilt: 24 - Sayı: 1, 53–56. https://ajindex.com/articles/181521

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Kaynakça (10)

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