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AI InsightIn conclusion, the combination of lidocaine-meperidine produced analgesia of quicker onset and longer duration than did lidocaine administered alone for caudal epidural analgesia in mares.
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Özet
The objectives of this study were to compare some haemodynamic and clinical parameters and the analgesic, sedative effects of lidocaine and a lidocaine-meperidine combination for caudal epidural analgesia in mares. This study was performed on 12 thoroughbred mares aged 13-24 years. Time to onset of analgesia in the combination group (6.67 ± 0.42 min) was significantly (P < 0.01) lower than in the lidocaine group (12.17 ± 1.05 min). However, duration of analgesia was significantly (P < 0.001) longer for the combination group (162.67 ± 5.67 min) than for the lidocaine group (109.33 ± 3.29 min). Heart and respiratory rates, rectal temperature, pH, pO2, pCO2, HCO3, BE, PCV, THb and O2Hb values measured before and after administrations in both groups were not significantly different. In conclusion, the combination of lidocaine-meperidine produced analgesia of quicker onset and longer duration than did lidocaine administered alone for caudal epidural analgesia in mares.
Abstract
The objectives of this study were to compare some haemodynamic and clinical parameters and the analgesic, sedative effects of lidocaine and a lidocaine-meperidine combination for caudal epidural analgesia in mares. This study was performed on 12 thoroughbred mares aged 13-24 years. Time to onset of analgesia in the combination group (6.67 ± 0.42 min) was significantly (P < 0.01) lower than in the lidocaine group (12.17 ± 1.05 min). However, duration of analgesia was significantly (P < 0.001) longer for the combination group (162.67 ± 5.67 min) than for the lidocaine group (109.33 ± 3.29 min). Heart and respiratory rates, rectal temperature, pH, pO2, pCO2, HCO3, BE, PCV, THb and O2Hb values measured before and after administrations in both groups were not significantly different. In conclusion, the combination of lidocaine-meperidine produced analgesia of quicker onset and longer duration than did lidocaine administered alone for caudal epidural analgesia in mares.