Dergiler / Haseki Tıp Bülteni / 2019 / Cilt: 57 - Sayı: 3

Association Between Cardiothoracic Ratio and Mortality in Neonates with Pneumothorax

Pnömotorakslı Yenidoğanlarda Kardiyotorasik Oran ve Mortalite Arasındaki İlişki

Sayfa
215–220
DOI
—
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Conclusion: A CTR below 0.4% can be considered an important parameter indicating an increased risk of mortality in newborns with pneumothorax

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Aim: The aim of this study was to determine the effect of a reduction in the cardiothoracic ratio (CTR) on mortality in newborns with pneumothorax.
📊
Temel Bulgular & Veri:Results: Of 7909 infants admitted to our neonatal intensive care unit from September 2006 to September 2017, a total of 82 (1.03%) newborns had pneumothorax.
💡
Sonuç & Katkı:Conclusion: A CTR below 0.4% can be considered an important parameter indicating an increased risk of mortality in newborns with pneumothorax
🔬Tür:Araştırma Makalesi
📍Kapsam:2006 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Aim: The aim of this study was to determine the effect of a reduction in the cardiothoracic ratio (CTR) on mortality in newborns with pneumothorax. Methods: Newborns with pneumothorax, who were admitted to our neonatal intensive care unit, were included in the study. The cardiothoracic ratio was calculated by dividing the transverse cardiac diameter by maximum internal thoracic diameter. Results: Of 7909 infants admitted to our neonatal intensive care unit from September 2006 to September 2017, a total of 82 (1.03%) newborns had pneumothorax. Patients who died had a lower CTR than surviving patients (0.39±0.056 and 0.44±0.048, respectively; p<0.001). It was found that the cut-off value was 0.4, area under the curve (AUC) value was 0.79, sensitivity was 68%, specificity was 87.7%, positive predictive value was 70.8%, and negative predictive value was 86.2%. Low birth weight, preterm birth, low maternal age, presence of respiratory distress syndrome, need for resuscitation at birth, and invasive mechanical ventilation were found to be significantly associated with mortality. However, among overall significant parameters, CTR and implementation of resuscitation at birth were the independent prognostic factors determined by regression analysis (p=0.001 and p=0.036, respectively). Conclusion: A CTR below 0.4% can be considered an important parameter indicating an increased risk of mortality in newborns with pneumothorax

Abstract

Amaç: Bu çalışmanın amacı pnömotoraks gelişen yenidoğan hastalarda kardiyotorasik oran (KTO) azalma oranının mortaliteyi belirleme üzerine etkisinin ortaya konulmasıdır. Yöntemler: Yenidoğan yoğun bakım ünitemize pnömotoraks ile takip edilen yenidoğan bebekler çalışmaya dahil edildi. Kardiyotorasik oran hesabı göğüs grafisinden mediastenin ortasından çizilen dikey bir çizgiye kalbin en sağ ve en sol noktasından çizilen dik çizgilerin toplamları, diyafragmaya teğet olarak çizilip kostaların iç sınırlarına kadar uzanan toraks çapına bölünerek bulundu. Bulgular: Eylül 2006’dan Eylül 2017 tarihleri arasında yenidoğan yoğun bakım ünitesine 7909 bebek başvurdu, 82’sinde (%1,03) pnömotoraks gelişti. Genel mortalite oranı %30 idi. Ölen hastalar, hayatta kalanlara göre daha düşük KTO’ya sahiptiler (sırasıyla, 0,39±0,056 ve 0,44±0,048, p<0001). Cut-off değeri 0,4, eğri altında kalan (AUC) değeri 0,79, duyarlılık %68, özgüllük %87,7, pozitif öngörü değeri %70,8, negatif öngörü değeri %86,2 olarak bulundu. Düşük doğum ağırlığı, preterm doğum, düşük maternal yaş, RDS varlığı, doğumda resüsitasyon ihtiyacı ve invaziv mekanik ventilasyonun mortalite ile anlamlı derecede ilişkili olduğu bulunmuştur. Bununla birlikte, genel anlamlı parametreler arasında, KTO ve doğumda resüsitasyonun uygulanması, regresyon analizi ile bağımsız prognostik faktörlerdir (sırasıyla, p=0,001 ve p=0,036). Sonuç: Pnömotorakslı yenidoğanlarda KTO’nun 0,4’ün altında olması mortalite riskinin arttığını gösteren önemli bir parametre olarak kabul edilebilir.

🔖

Bu Makaleye Atıf Yap

YILMAZ, F. H., TARAKÇI, N. E., GÜLTEKİN, N. D., GÜLTEKİN, Ü., ALTUNHAN, H. (2019). Association Between Cardiothoracic Ratio and Mortality in Neonates with Pneumothorax. Haseki Tıp Bülteni, Cilt: 57 - Sayı: 3, 215–220. https://ajindex.com/articles/172789

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (18)

  1. Jeng MJ, Lee YS, Tsao PC et al. Neonatal air leak syndrome and the role of high-frequency ventilation in its prevention. J Chin Med Assoc 2012;75:551-9
  2. Edwards MO, Kotecha SJ, Kotecha S. Respiratory distress of the term newborn infant. Paediatr Respir Rev 2013;14:29-36; quiz 36-7
  3. Terzic S, Heljic S. Assessing mortality risk in very low birth weight infants. Med Arh. 2012;66:76-9
  4. Al Tawil K, Abu-Ekteish FM, Tamimi O, et al. Symptomatic spontaneous pneumothorax in term newborn infants. Pediatr Pulmonol 2004;37:443-6
  5. Powers WF, Clemens JD. “Prognostic implications of age at detection of air leak in very low birth weight infants requiring ventilatory support.” J Pediatr 1993;123:611-7
  6. Inouea K, Yoshiib K, Itob H. Effect of Aging on Cardiothoracic Ratio in Women: A Longitudinal Study. Gerontology 1999;45:53-8
  7. Danzer CS. The cardiothoracic ratio. An index of cardiac enlargement. Am J Med Sci 1919;157:513-21
  8. Hada Y. Cardiothoracic ratio. J Cardiol 1995;26:51-4
  9. Ito K, Ookawara S, Ueda Y et al. A Higher Cardiothoracic Ratio Is Associated with 2-Year Mortality after Hemodialysis Initiation. Nephron Extra 2015;19:100-10
  10. Ilçe Z, Gündogdu G, Kara C et al. “Which patients are at risk? Evaluation of the morbility and mortality in newborn pneumothorax.” Indian Pediatr 2003;40:325-8
  11. Ozer EA, Ergin AY et al. Is pneumothorax size on chest x-ray a predictor of neonatal mortality? Iran J Pediatr 2013;23:541-5
  12. Katar S, Devecioğlu C, Kervancioğlu M. Symptomatic spontaneous pneumothorax in term newborns. Pediatr Surg Int 2006;22:755-8
  13. Ogata ES, Gregory GA, Kitterman JA, et al. Pneumothorax in the respiratory distress syndrome: incidence and effect on vital signs, blood gases and pH. Pediatrics 1976;58:177-83
  14. Stoll BJ, Kliegman RM. Extrapulmonary extravasation of air. In: Behrman RE, Kliegman RM, Jenson HB (eds). Nelson Textbook of Pediatrics. 17th ed. Philadelphia: WB Saunders, 2004:586-7
  15. Kolas T, Saugstad OD, Daltveit AK, et al. Planned cesarean versus planned vaginal delivery at term: comparison of newborn infant outcomes. Am J Obstet Gynecol 2006;195:1538-43
  16. Horbar JD1, Badger GJ, Carpenter JH et al. Trends in mortality and morbidity for very low birth weight infants, 1991-1999. Pediatrics 2002;110 (1Pt 1):143-51
  17. Morley CJ1, Davis PG, Doyle LW et al.“ Nasal CPAP or intubation at birth for very preterm infants.” N Engl J Med 2008;358:700-8
  18. Ceylan A, Gezer S, Demir N. The importance of administration