Dergiler / Journal of Urological Surgery / 2020 / Cilt: 7 - Sayı: 2

Incidental Prostate Adenocarcinoma in Prostate Transurethral Resections: Our Eight Year Experience

Prostat Transüretral Rezeksiyonlarında Rastlantısal Prostat Adenokarsinomu: Sekiz Yıllık Deneyimimiz

Sayfa
88–91
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In these patients, preoperative serum PSA levels were lower than those without tumor. histopathological examination of all TURP materials, especially those obtained in patients of advanced age undergoing TURP with, a preliminary diagnosis of BPH, are important in terms of avoiding underdiagnosis.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: Incidental early-stage prostate cancer (PC) can be detected in patients undergoing transurethral resection of the prostate (TURP) due to benign prostatic hyperplasia (BPH).
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Temel Bulgular & Veri:Materials and Methods: A total of 391 patients, who underwent TURP for BPH in our hospital between 2011 and 2018, were included in the study.
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Sonuç & Katkı:In these patients, preoperative serum PSA levels were lower than those without tumor. histopathological examination of all TURP materials, especially those obtained in patients of advanced age undergoing TURP with, a preliminary diagnosis of BPH, are important in terms of avoiding underdiagnosis.
🔬Tür:Araştırma Makalesi
📍Kapsam:2011 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: Incidental early-stage prostate cancer (PC) can be detected in patients undergoing transurethral resection of the prostate (TURP) due to benign prostatic hyperplasia (BPH). In our study, we investigated the incidence of incidental PC and the relationship of the incidence of PC with age, serum prostate specific antigen (PSA) levels and resected prostate tissue volume in patients undergoing TURP for BPH. Materials and Methods: A total of 391 patients, who underwent TURP for BPH in our hospital between 2011 and 2018, were included in the study. Age and volumes of resection materials of the cases were obtained from pathology reports and blood PSA levels were obtained from the urology clinic. Results: In our series, incidental PC was detected in 17 of 391 cases (4.3%). The mean age of the patients with and without tumor was 74.5 years 69.5 years, respectively. The mean preoperative PSA level was 5.05 ng/mL in 226 patients without PC and the mean preoperative PSA level was 4.46 ng/mL in 15 patients with PC whose preoperative PSA levels could be checked by the urology clinic. Conclusion: In our study, incidental PC detection rate (<5%) in surgical specimens of patients undergoing TURP for BPH was found to be compatible with the literature. The incidence of PC was found to be higher, especially in patients aged 70 years and older. In these patients, preoperative serum PSA levels were lower than those without tumor. histopathological examination of all TURP materials, especially those obtained in patients of advanced age undergoing TURP with, a preliminary diagnosis of BPH, are important in terms of avoiding underdiagnosis.

Abstract

Amaç: Rastlantısal erken evre prostat kanseri (PK), benign prostat hiperplazisi (BPH) nedeniyle transüretral prostat rezeksiyonu (TURP) yapılan hastalarda tespit edilebilir. Çalışmamızda hastanemizde BPH nedeniyle TURP uygulanan hastalarda rastlantısal PK insidansı ve yaş, rezeke prostat dokusu hacmi ve serum prostat spesifik antijen (PSA) düzeyleri arasındaki ilişkiyi araştırdık. Gereç ve Yöntem: Çalışmamıza 2011 ve 2018 yılları arasında hastanemizde BPH nedeniyle TURP uygulanan 391 hasta dahil edildi. Olguların yaş ve TURP hacimleri patoloji raporlarından, serum PSA düzeyleri üroloji kliniğinden elde edildi. Bulgular: Serimizdeki 391 olgunun 17’sinde (%4,3) rastlantısal PK tespit edildi. Tümörü olan hastaların yaş ortalaması 74,5, tümörü olmayanların yaş ortalaması 69,5 idi. Preoperatif PSA düzeyleri 226 hastada ortalama 5.05 ng/mL iken, PK’li 15 hastada ortalama PSA düzeyi 4.46 ng/mL idi. Sonuç: Çalışmamızda BPH için TURP materyallerinde rastlantısal PK saptama oranı (<%5) literatürle paralel bulundu. Rastlantısal PK insidansı, özellikle 70 yaş ve üstü olgularda daha yüksek bulunmuştur. Bu hastalarda preoperatif serum PSA düzeyleri tümörsüzlere göre düşüktü. Bu, tüm TURP materyalinin, histopatolojik incelenmesi, özellikle de BPH ön tanısıyla yapılan ileri yaştakilerin, tümörü atlamama açısından önemli olduğunu göstermektedir.

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Bu Makaleye Atıf Yap

SAYAR, H. C., EKMEKÇİ, S., ÇAKMAK, Ö., KÜÇÜK, Ü. (2020). Incidental Prostate Adenocarcinoma in Prostate Transurethral Resections: Our Eight Year Experience. Journal of Urological Surgery, Cilt: 7 - Sayı: 2, 88–91. https://ajindex.com/articles/165271

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Kaynakça (5)

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