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Dergiler / Pamukkale Journal of Sport Sciences / 2026 / Volume: 11 Issue: 2

Collagen type I alpha 1 (COL1A1) rs1800012 polymorphism in cyclists

Beste Tacal Aslan(FACULTY OF DENTISTRY)0000-0001-5271-7917
Başak Funda Eken(FACULTY OF DENTISTRY)
Tugba Kaman(USKUDAR UNIVERSITY)
Canan Sercan(USKUDAR UNIVERSITY)0000-0002-2218-2234
Korkut Ulucan(FACULTY OF DENTISTRY)0000-0002-1304-9386
Sayfa
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Yayın Tarihi
2020-05-29
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Larger homogenous cohorts may help clarify the association between COL1A1 rs1800012 polymorphism and physical performance.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Purpose: We suggested that polymorphic differences affect the performance of cyclists.
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Temel Bulgular & Veri:In this study we designed the experiment to identify collagen type I alpha 1 (COL1A1) rs1800012 polymorphism in cyclists.
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Sonuç & Katkı:Larger homogenous cohorts may help clarify the association between COL1A1 rs1800012 polymorphism and physical performance.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:collagen type I alpha I · polymorphism · cycling

Abstract

Purpose: We suggested that polymorphic differences affect the performance of cyclists. In this study we designed the experiment to identify collagen type I alpha 1 (COL1A1) rs1800012 polymorphism in cyclists. Methods: We isolated genomic DNA from buccal epithelial cells of 38 cyclists. We followed COL1A1 rs1800012 single nucleotide polymorphism genotyping technology protocol. We reported allele frequencies for rs1800012 gene variants of cyclists in our kohort. Results: Our results indicated the differences of the distribution of COL1A1 rs1800012 SNP between cyclists. The numbers and percentages of CC, AC and AA genotypes for rs1800012 polymorphism that we obtained were 24 (63%), 13 (34%) and 1 (3%), respectively. The distributions of C and A alleles were counted as 61 (80%) and 15 (20%). Conclusions: There was difference in the genotype and also allele distribution between cyclists. Carriers of a C allele as compared to carriers of the allele A are more prone to cyclism. Larger homogenous cohorts may help clarify the association between COL1A1 rs1800012 polymorphism and physical performance.

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Bu Makaleye Atıf Yap

Aslan, B. T., Eken, B. F., Kaman, T., Sercan, C., Ulucan, K. (2020). Collagen type I alpha 1 (COL1A1) rs1800012 polymorphism in cyclists. Pamukkale Journal of Sport Sciences, Volume: 11 Issue: 2. https://ajindex.com/articles/1633787

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Kaynakça (13)

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