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Dergiler / Kafkas Journal of Medical Sciences / 2026 / Cilt: 16 Sayı: 2

Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management

Ülkü Ayşe Türker Aras(Department of Obstetrics and Gynecology, Faculty of Medicine, Kafkas University, Kars)
Ezgi Dutoğlu(Gynecology and Obstetrics Clinic, Bilecik High Specialization Training and Research Hospital, Bilecik, Türkiye,)
Burcu Dinçgez(Gynecology and Obstetrics Clinic, Health Sciences University, Bursa High Specialization Training and Research Hospital, Bursa, Türkiye)
Sayfa
250–252
Yayın Tarihi
2026-08-06
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The potential causes of elevated CRP, even in unruptured ectopic pregnancies, and its relationship to treatment approaches are discussed.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:This case report presents the medical management of a 34-year-old patient diagnosed with an early-stage tubal ectopic pregnancy characterized by menstrual delay, mild pelvic pain, and elevated C-reactive protein (CRP) levels in laboratory findings, but no signs of rupture.
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Temel Bulgular & Veri:This case report presents the medical management of a 34-year-old patient diagnosed with an early-stage tubal ectopic pregnancy characterized by menstrual delay, mild pelvic pain, and elevated C-reactive protein (CRP) levels in laboratory findings, but no signs of rupture.
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Sonuç & Katkı:The potential causes of elevated CRP, even in unruptured ectopic pregnancies, and its relationship to treatment approaches are discussed.
🔬Tür:Olgu Sunumu
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Ectopic pregnancy · CRP · Rupture

Abstract

This case report presents the medical management of a 34-year-old patient diagnosed with an early-stage tubal ectopic pregnancy characterized by menstrual delay, mild pelvic pain, and elevated C-reactive protein (CRP) levels in laboratory findings, but no signs of rupture. The potential causes of elevated CRP, even in unruptured ectopic pregnancies, and its relationship to treatment approaches are discussed.

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Bu Makaleye Atıf Yap

Aras, Ü. A. T., Dutoğlu, E., Dinçgez, B. (2026). Elevated CRP Levels in Early-Diagnosed, Unruptured Tubal Ectopic Pregnancy: A Potential for Conservative Management. Kafkas Journal of Medical Sciences, Cilt: 16 Sayı: 2, 250–252. https://ajindex.com/articles/1631478

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Kaynakça (8)

  1. American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins -Gynecology. ACOG Practice Bulletin No. 193: Tubal Ectopic Pregnancy. Obstet Gynecol. 2018;131:91–103. https://doi.org/10.1097/AOG.0000000000002560
  2. Baggio S, Garzon S, Russo A, Ianniciello CQ, Santi L, Laganà AS, et al. Fertility and reproductive outcome after tubal ectopic pregnancy: comparison among methotrexate, surgery and expectant management. Arch Gynecol Obstet. 2021;303:259–268. https://doi.org/10.1007/s00404-020-05749-2
  3. RG, TD. 3-year analysis of prognostic factors affecting success in single-dose methotrexate treatment: A single-center experience. Perinatol J. 2018;26:2–3. https://doi.org/10.2399/ prn.18.0262006
  4. Mullany K, Minneci M, Monjazeb R, C Coiado O. Overview of ectopic pregnancy diagnosis, management, and innovation. Womens Health (Lond). 2023;19:1–2. https://doi.org/10.1177/17455057231160349
  5. Cohen Y, Ascher-Landsberg J, Cohen A, Lessing JB, Grisaru D. The role of C-reactive protein measurement as a diagnostic aid in early pregnancy. Eur J Obstet Gynecol Reprod Biol. 2014;176:64–67. https://doi.org/10.1016/j.ejogrb.2014.03.004
  6. Theron GB, Shepherd EG, Strachan AF. C-reactive protein levels in ectopic pregnancy, pelvic infection and carcinoma of the cervix. S Afr Med J. 1986;24:681–682.
  7. Drugs and Lactation Database (LactMed®). Bethesda (MD): National Institute of Child Health and Human Development;Methotrexate. https://www.ncbi.nlm.nih.gov/books/ NBK501341/
  8. Sacks GP, Seyani L, Lavery S, Trew G. Maternal C-reactive protein levels are raised at 4 weeks gestation. Hum Reprod. 2004;19:1025–1030. https://doi.org/10.1093/humrep/ deh179