Dergiler / Molecular Oncologic Imaging / 2024 / Volume: 4 Issue: 3

Comparison of Static and Spect Images on Tc-99m-PYP Bone Scintigraphy in the Diagnosis of Cardiac Amyloidosis

Emine Aydın Akpınar(MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÜKLEER TIP ANABİLİM DALI)
Pınar Pelin Özcan(MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÜKLEER TIP ANABİLİM DALI)
Zehra Pınar Koç(MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÜKLEER TIP ANABİLİM DALI)
Adil Gümüş(MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÜKLEER TIP ANABİLİM DALI)
Gökçe Yavan(MERSİN ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ, NÜKLEER TIP ANABİLİM DALI)0000-0002-7332-6293
Sayfa
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Yayın Tarihi
2025-01-14
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In our study, we compared the 1st and 3rd hour planar and SPECT imaging to investigate the importance of the 3rd hour and the necessity of SPECT in cardiac amyloidosis (CA) imaging, which is one of the controversial topics from the Nuclear Medicine perspective.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Amyloidosis is a systemic disease characterized by the extracellular accumulation of amyloid fibrils caused by misfolding of proteins.
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Temel Bulgular & Veri:Scintigraphic imaging with Technetium (Tc-99m) labelled biphosponates may faciliate early detection of cardiac involvement and distinguish various forms of cardiac amyloidosis.
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Sonuç & Katkı:In our study, we compared the 1st and 3rd hour planar and SPECT imaging to investigate the importance of the 3rd hour and the necessity of SPECT in cardiac amyloidosis (CA) imaging, which is one of the controversial topics from the Nuclear Medicine perspective.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:cardiac amyloidosis · Tc-99m PYP · SPECT

Abstract

Amyloidosis is a systemic disease characterized by the extracellular accumulation of amyloid fibrils caused by misfolding of proteins. Cardiac amyloidosis has the worst prognosis of the type of organ involvements. The most common forms of cardiac amyloidosis are immunoglobulin light chain amyloidosis (AL) and transtretin (TTR) amyloidosis. The developing diagnostic methods give the clinician early diagnosis of cardiac amyloidosis. Scintigraphic imaging with Technetium (Tc-99m) labelled biphosponates may faciliate early detection of cardiac involvement and distinguish various forms of cardiac amyloidosis. Bone scintigraphy for evaluation of cardiac amyloidosis especially for ATTR type amyloidosis is one of the most sensitive imaging prosedures in recent years. In our study, we compared the 1st and 3rd hour planar and SPECT imaging to investigate the importance of the 3rd hour and the necessity of SPECT in cardiac amyloidosis (CA) imaging, which is one of the controversial topics from the Nuclear Medicine perspective.

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Bu Makaleye Atıf Yap

Akpınar, E. A., Özcan, P. P., Koç, Z. P., Gümüş, A., Yavan, G. (2025). Comparison of Static and Spect Images on Tc-99m-PYP Bone Scintigraphy in the Diagnosis of Cardiac Amyloidosis. Molecular Oncologic Imaging, Volume: 4 Issue: 3. https://doi.org/10.71286/moi.1534280

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Kaynakça (12)

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