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Dergiler / Uluslararası Bilim Teknoloji ve Tasarım Dergisi / 2026 / Cilt: 6 Sayı: 1

Investigation of the effects of anesthetic inhalation agents with certain biochemical and hematological parameters

Fatma Arı(BURSA ULUDAG UNIVERSITY)0009-0001-8950-6731
Egemen Dere(Bursa Uludağ Üniversitesi)0000-0001-9572-1051
Sayfa
20–33
Yayın Tarihi
2025-06-30
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Only the enzymes we studied, AST and LDH in women and ALT in men, showed significant results compared to the control group, while Na and K were found to be significant in men (p<0.05).

📌 3 Maddede Bu Makale

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Amaç & Hipotez:In this study, the effects of sevoflurane, desflurane and isoflurane on the personnel working in 4 different hospitals were investigated with some biochemical and hematological parameters.
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Temel Bulgular & Veri:A total of 60 anesthesia technicians working in 42 operating rooms were divided into 3 experimental periods, 6-10, 11-15 and 16-20 years, depending on the duration of exposure to the anesthetic agent. 60 individuals with different professions, in the same age range as the experimental group, were selected as the control group.
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Sonuç & Katkı:Only the enzymes we studied, AST and LDH in women and ALT in men, showed significant results compared to the control group, while Na and K were found to be significant in men (p<0.05).
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Desflurane · enzyme · isoflurane

Özet

In this study, the effects of sevoflurane, desflurane and isoflurane on the personnel working in 4 different hospitals were investigated with some biochemical and hematological parameters. A total of 60 anesthesia technicians working in 42 operating rooms were divided into 3 experimental periods, 6-10, 11-15 and 16-20 years, depending on the duration of exposure to the anesthetic agent. 60 individuals with different professions, in the same age range as the experimental group, were selected as the control group. In blood samples, ALT, AST, ALP, CK, LDH, GST and amylase activities and Na+, K+, CK-MB, glucose, urea, total protein, total bilirubin, total cholesterol, triglyceride, leukocyte, erythrocyte and platelet amounts were measured. Although values outside the normal limits were occasionally observed in the 120 individuals studied, the average of all parameters measured for 1 year was found to be within normal values in both the control and experimental groups. Only the enzymes we studied, AST and LDH in women and ALT in men, showed significant results compared to the control group, while Na and K were found to be significant in men (p<0.05).

Abstract

In this study, the effects of sevoflurane, desflurane and isoflurane on the personnel working in 4 different hospitals were investigated with some biochemical and hematological parameters. A total of 60 anesthesia technicians working in 42 operating rooms were divided into 3 experimental periods, 6-10, 11-15 and 16-20 years, depending on the duration of exposure to the anesthetic agent. 60 individuals with different professions, in the same age range as the experimental group, were selected as the control group. In blood samples, ALT, AST, ALP, CK, LDH, GST and amylase activities and Na+, K+, CK-MB, glucose, urea, total protein, total bilirubin, total cholesterol, triglyceride, leukocyte, erythrocyte and platelet amounts were measured. Although values outside the normal limits were occasionally observed in the 120 individuals studied, the average of all parameters measured for 1 year was found to be within normal values in both the control and experimental groups. Only the enzymes we studied, AST and LDH in women and ALT in men, showed significant results compared to the control group, while Na and K were found to be significant in men (p<0.05).

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Bu Makaleye Atıf Yap

Arı, F., Dere, E. (2025). Investigation of the effects of anesthetic inhalation agents with certain biochemical and hematological parameters. Uluslararası Bilim Teknoloji ve Tasarım Dergisi, Cilt: 6 Sayı: 1, 20–33. https://ajindex.com/articles/1623202

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