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Dergiler / Rize Tıp Dergisi / 2026 / Cilt: 1 Sayı: 1

Blood Apelin-36 Level in Patients with Depression

Meltem Puşuroğlu(RECEP TAYYİP ERDOĞAN ÜNİVERSİTESİ, TIP FAKÜLTESİ)
İlkay Bahçeci(RECEP TAYYİP ERDOĞAN ÜNİVERSİTESİ, TIP FAKÜLTESİ)
Mehmet Baltacıoğlu(RECEP TAYYİP ERDOĞAN ÜNİVERSİTESİ, TIP FAKÜLTESİ)
Bülent Bahçeci(RECEP TAYYİP ERDOĞAN ÜNİVERSİTESİ, TIP FAKÜLTESİ)
Yunus Emre İbik(RECEP TAYYİP ERDOĞAN ÜNİVERSİTESİ, TIP FAKÜLTESİ)
Sayfa
1–8
Yayın Tarihi
2024-03-20
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In this respect, our research contributes to the literature.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Abstract Aim: Major Depressive Disorder is an important health problem leading to significant disability.
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Temel Bulgular & Veri:Materials and Methods: The study included 30 patients diagnosed with Major Depressive Disorder and 31 healthy controls.
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Sonuç & Katkı:In this respect, our research contributes to the literature.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Depression · Apelin · Mood Disorders

Abstract

Abstract Aim: Major Depressive Disorder is an important health problem leading to significant disability. Biochemical parameters that can be used in the diagnosis and follow-up of Major Depressive Disorders severity are important for clinicians. The aim of our study was to investigate blood apelin levels in patients with Major Depressive Disorder as a marker for disease severity and diagnosis. Materials and Methods: The study included 30 patients diagnosed with Major Depressive Disorder and 31 healthy controls. Hamilton Depression Scale was applied to the patient group. Blood apelin-36 levels were measured in both groups. Results: Plasma apelin-36 level was 0.363±0.102 ng/ml (min-max: 0.173-0.611) in the patient group and 1.140±0.738 ng/ml (min-max: 0.323-2.547) in the healthy control group. Blood apelin-36 level of the patient group was statistically significantly lower than that of the healthy control group (p<0.001). Conclusion: Blood apelin levels were found to be low in patients with Major Depressive Disorder. Apelin is an endogenous peptide with important physiological roles and looks promising as a biomarker. It’s utility for the diagnosis and follow-up of mood disorders requires further investigation. In this respect, our research contributes to the literature.

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Bu Makaleye Atıf Yap

Puşuroğlu, M., Bahçeci, İ., Baltacıoğlu, M., Bahçeci, B., İbik, Y. E. (2024). Blood Apelin-36 Level in Patients with Depression. Rize Tıp Dergisi, Cilt: 1 Sayı: 1, 1–8. https://ajindex.com/articles/1620554

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