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Dergiler / Atlas Journal of Medicine / 2026 / Cilt: 6 Sayı: 1

Alerjik hastalıkların yönetiminde seçilmiş besin takviyeleri: probiyotikler, D vitamini, C vitamini ve çörek otu

Selected Dietary Supplements in the Management of Allergic Diseases: Probiotics, Vitamin D, Vitamin C and Nigella sativa

Sena Çağan(İstanbul Atlas Üniversitesi)0009-0000-5520-6813
Ayşe Betül Bilen(İstanbul Atlas Üniversitesi)0000-0003-2765-2677
Sayfa
45–51
Yayın Tarihi
2026-02-27
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Literatürde bu takviyelerin bir kısmının Th2 yanıtını baskılayarak, IgE üretimini azaltarak ve epitel bariyer bütünlüğünü koruyarak alerjik hastalıklara karşı etki gösterebilecekleri sonucuna varılmıştır.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Alerjik hastalıklar, özellikle son yıllarda hem gelişmiş hem de gelişmekte olan ülkelerde prevalansı artan, yaşam kalitesini ciddi şekilde etkileyen bağışıklık sistemi temelli kronik hastalıklardır.
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Temel Bulgular & Veri:Bu derlemede; probiyotikler, D vitamini, C vitamini ve çörek otu gibi sıkça araştırmalara konu olan ve potansiyel koruyucu etkileri bulunan takviyeler incelenmiştir.
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Sonuç & Katkı:Literatürde bu takviyelerin bir kısmının Th2 yanıtını baskılayarak, IgE üretimini azaltarak ve epitel bariyer bütünlüğünü koruyarak alerjik hastalıklara karşı etki gösterebilecekleri sonucuna varılmıştır.
🔬Tür:Deneysel Tarla Denemesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alerjik Hastalıklar · Probiyotikler · D vitamini

Özet

Alerjik hastalıklar, özellikle son yıllarda hem gelişmiş hem de gelişmekte olan ülkelerde prevalansı artan, yaşam kalitesini ciddi şekilde etkileyen bağışıklık sistemi temelli kronik hastalıklardır. Genetik yatkınlık, çevresel maruziyetler ve immün dengenin bozulması ile şekillenen bu hastalıklarda, beslenme ve mikro besin desteği bağışıklık sisteminin düzenlenmesinde önemli rol oynamaktadır. Bu derlemede; probiyotikler, D vitamini, C vitamini ve çörek otu gibi sıkça araştırmalara konu olan ve potansiyel koruyucu etkileri bulunan takviyeler incelenmiştir. Literatürde bu takviyelerin bir kısmının Th2 yanıtını baskılayarak, IgE üretimini azaltarak ve epitel bariyer bütünlüğünü koruyarak alerjik hastalıklara karşı etki gösterebilecekleri sonucuna varılmıştır. Ancak çalışmalardaki metodolojik farklılıklar, hasta grubu çeşitliliği ve dozaj farkları, elde edilen sonuçların genellenebilirliğini sınırlamaktadır.

Abstract

Allergic diseases are immune system-based chronic diseases that have increased in prevalence in both developed and developing countries in recent years and seriously affect the quality of life. In these diseases shaped by genetic predisposition, environmental exposures and impaired immune balance, nutrition and micronutrient support play an important role in the regulation of the immune system. In this review, supplements such as probiotics, vitamin D, vitamin C and black cumin seed, which are frequently researched and have potential protective effects, were analysed. In the literature, it has been concluded that some of these supplements may be effective against allergic diseases by suppressing Th2 response, reducing IgE production and protecting epithelial barrier integrity. However, methodological differences, patient group diversity and dosage differences in the studies limit the generalisability of the results obtained.

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Bu Makaleye Atıf Yap

Çağan, S., Bilen, A. B. (2026). Alerjik hastalıkların yönetiminde seçilmiş besin takviyeleri: probiyotikler, D vitamini, C vitamini ve çörek otu. Atlas Journal of Medicine, Cilt: 6 Sayı: 1, 45–51. https://doi.org/10.54270/atljm.2026.108

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