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Dergiler / GORM:Gynecology Obstetrics & Reproductive Medicine / 2019 / Cilt: 25 - Sayı: 1

Impact of the Duration of Controlled Ovarian Stimulation on Assisted Reproduction Cycle Outcomes

İnci KAHYAOĞLU
HATİCE YILMAZ DOĞRU
İskender KAPLANOĞLU
SERDAR DİLBAZ
Leyla MOLLAMAHMUTOĞLU
Sayfa
28–32
DOI
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CONCLUSION: Prolonged cycles have a detrimental effect only on ongoing pregnancy rates in poor re- sponders.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:OBJECTIVE: To investigate the impact of duration of controlled ovarian stimulation in vitro fertilization outcomes.
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Temel Bulgular & Veri:STUDY DESIGN: Medical records of 3194 in vitro fertilization and intra cytoplasmic sperm injection cycles from the assisted reproduction unit of a tertiary hospital were retrospectively analyzed using a com- puter-based database.
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Sonuç & Katkı:CONCLUSION: Prolonged cycles have a detrimental effect only on ongoing pregnancy rates in poor re- sponders.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

OBJECTIVE: To investigate the impact of duration of controlled ovarian stimulation in vitro fertilization outcomes. STUDY DESIGN: Medical records of 3194 in vitro fertilization and intra cytoplasmic sperm injection cycles from the assisted reproduction unit of a tertiary hospital were retrospectively analyzed using a com- puter-based database. Characteristics of cycles with duration of stimulation ≤8 days (group I), 9 to 12 days (group II) or ≥13 days (group III) were studied retrospectively. Subgroup analysis was also done for poor responders, patients with polycystic ovary syndrome and normoresponders. RESULTS: Estradiol on trigger day, the number of retrieved oocytes, mature oocytes and fertilized oocytes were significantly higher in group II compared to the other two groups when all cycles were analyzed (p<0.001). No significant difference was observed regarding clinical and ongoing pregnancy rates between groups. Regarding poor responders, the number of mature oocytes and the number of fertil- ized oocytes were higher in group II compared to the other groups (p=0.028, p=0.038, respectively). Ongoing pregnancy rates were significantly lower in group III compared to other groups (p=0.041). In patients with polycystic ovary syndrome, number of retrieved oocytes was significantly lower in group III compared to group II (p=0.047) and number of mature oocytes was significantly lower in group III compared to the other groups (p=0.005). No significant difference was found in the clinical and ongoing pregnancy rates. The number of retrieved oocytes, clinical and ongoing pregnancy rates were comparable between three groups for normoresponders. CONCLUSION: Prolonged cycles have a detrimental effect only on ongoing pregnancy rates in poor re- sponders.

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Bu Makaleye Atıf Yap

KAHYAOĞLU, İ., DOĞRU, H. Y., KAPLANOĞLU, İ., DİLBAZ, S., MOLLAMAHMUTOĞLU, L. (2019). Impact of the Duration of Controlled Ovarian Stimulation on Assisted Reproduction Cycle Outcomes. GORM:Gynecology Obstetrics & Reproductive Medicine, Cilt: 25 - Sayı: 1, 28–32. https://ajindex.com/articles/160455

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Kaynakça (9)

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