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Dergiler / Journal of Pharmaceutical Technology / 2026 / Volume: 1 Issue: 1

An update on cyclodextrins as drug vehicles for antimicrobial applications

Ece Özcan Bülbül(ISTANBUL UNIVERSITY)0000-0001-7112-923X
Kalliopi Eleftherıadou(Aristotle University of Thessaloniki)0000-0003-3192-8269
Neslihan Üstündağ Okur(University of Health Sciences, Faculty of Pharmacy)0000-0002-3210-3747
Panoraia Siafaka(Aristotle University of Thessaloniki)0000-0001-7256-3230
Sayfa
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Yayın Tarihi
2020-04-01
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Regarding this, the most recent cyclodextrin inclusion complexes with antimicrobial and antifungal drugs are summarized in this article.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Cyclodextrins belong to cyclic oligosaccharides comprised of α-(1,4) linked glucopyranose groups.
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Temel Bulgular & Veri:Their interesting supramolecular cavity-like structure can host active molecules providing a breeding ground for drug delivery systems.
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Sonuç & Katkı:Regarding this, the most recent cyclodextrin inclusion complexes with antimicrobial and antifungal drugs are summarized in this article.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Antibacterial · Antifungal · Cyclodextrins

Abstract

Cyclodextrins belong to cyclic oligosaccharides comprised of α-(1,4) linked glucopyranose groups. Their interesting supramolecular cavity-like structure can host active molecules providing a breeding ground for drug delivery systems. Cyclodextrins, due to their unique functional structure, can produce host-guest complexes with active ingredients, such as drugs, peptides, proteins, etc.; the complexes resulted from intramolecular interactions leading to stable molecules vehicles. Moreover, cyclodextrins are already applied in pharmaceutical industry applications since they can induce the solubility of lipophilic compounds and provide bioavailability and excellent safety profile and stability. In this review, the basic background for cyclodextrins and their current applications in the antimicrobial field are discussed. Besides, the antibacterial and antifungal-applications in the pharmaceutical field attract most researchers because of microbes’ resistance. Regarding this, the most recent cyclodextrin inclusion complexes with antimicrobial and antifungal drugs are summarized in this article.

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Bu Makaleye Atıf Yap

Bülbül, E. Ö., Eleftherıadou, K., Okur, N. Ü., Siafaka, P. (2020). An update on cyclodextrins as drug vehicles for antimicrobial applications. Journal of Pharmaceutical Technology, Volume: 1 Issue: 1. https://doi.org/10.37662/jpt.2020.3

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