Dergiler / Endoskopi Gastrointestinal / 2020 / Cilt: 28 Sayı: Sayı: 3

Post-Endoskopik Retrograd Kolanjiyopankreatografi Pankreatitinde Olası Risk Faktörlerinin ve Prognostik Belirteçlerin Araştırılması

Investigating Possible Risk Factors and Prognostic Markers for Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Bahri Abaylı(ADANA SEYHAN DEVLET HASTANESİ)0000-0001-5583-8642
Genco Gencdal(ÜSKÜDAR ÜNİVERSİTESİ)0000-0002-5856-5384
Sayfa
77–81
Yayın Tarihi
2020-12-30
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Bu çalışmada AST, ALT, Wbc, nötrofil, nötrofil yüzdesi, lenfosit, lenfosit yüzdesi ve NLR değerlerinin PEP gelişen grupta PEP gelişmeyen gruba göre anlamlı derecede yüksek olduğunu bulduk.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Post- ERCP pankreatit (PEP), ERCP sonrası sık görülen komplikasyondur.
📊
Temel Bulgular & Veri:PEP ayrıca hastanede kalış süresini uzatır ve maliyetlerde artışa neden olur.
💡
Sonuç & Katkı:Bu çalışmada AST, ALT, Wbc, nötrofil, nötrofil yüzdesi, lenfosit, lenfosit yüzdesi ve NLR değerlerinin PEP gelişen grupta PEP gelişmeyen gruba göre anlamlı derecede yüksek olduğunu bulduk.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:ERCP · Pankreatit · ERCP

Özet

Post- ERCP pankreatit (PEP), ERCP sonrası sık görülen komplikasyondur. PEP genellikle hafiftir, ancak bazen hayatı tehdit eden bir klinik tablo olabilir. PEP ayrıca hastanede kalış süresini uzatır ve maliyetlerde artışa neden olur. PEP için olası risk faktörlerini ve prognostik belirteçleri araştırmak üzere ERCP sonuçlarmızı değerlendirmeyi amaçladık. Bu çalışmada AST, ALT, Wbc, nötrofil, nötrofil yüzdesi, lenfosit, lenfosit yüzdesi ve NLR değerlerinin PEP gelişen grupta PEP gelişmeyen gruba göre anlamlı derecede yüksek olduğunu bulduk.

Abstract

Post-ERCP pancreatitis (PEP) is the most common postoperative complication. PEP is often mild, but sometimes may be a life-threatening clinical picture. PEP also increases the length of hospitalization and causes an increase in costs. We aimed to present the ERCP results of our hospital and second to investigate the possible risk factors and prognostic markers for PEP. We found AST, ALT, Wbc, neutrophil, neutrophil percentage, lymphocyte, lymphocyte percentage, and NLR values were significantly higher in PEP group than the other group in this study.

🔖

Bu Makaleye Atıf Yap

Abaylı, B., Gencdal, G. (2020). Post-Endoskopik Retrograd Kolanjiyopankreatografi Pankreatitinde Olası Risk Faktörlerinin ve Prognostik Belirteçlerin Araştırılması. Endoskopi Gastrointestinal, Cilt: 28 Sayı: Sayı: 3, 77–81. https://doi.org/10.17940/endoskopi.753336

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (31)

  1. Rodrigues-Pinto E, Macedo G, Baron TH. ERCP competence assessment: miles to go before standardization. Endosc Int Open 2017; 5: E718-E721.
  2. Matsushita M, Koyabu M, Nishio A, Seki T, Okazaki K. Techniques of ERCP with a conventional endoscope in pancreatoduodenectomy anatomy. Gastrointest Endosc 2017; 86: 747-748.
  3. Mine T, Morizane T, Kawaguchi Y,, Akashi R, Hanada K, Ito T, et al. Clinical practice guideline for post-ERCP pancreatitis. J Gastroenterol 2017 Jun 26. doi: 10.1007/s00535-017- 1359-5. [Epub ahead of print].
  4. Wang AY. Medications and methods for the prevention of Post-ERCP pancreatitis. GastroenterolHepatol (N Y) 2017; 13: 188-191.
  5. Wilcox CM. Prevention of post-ERCP pancreatitis is more than just suppositories and stents. DigEndosc 2017; 29: 758-760.
  6. Loperfido S, Angelini G, Benedetti G, Chilovi F, Costan F, De Berardinis F, et al. Major early complications from diagnostic and therapeutic ERCP: a prospective multicenter study. Gastrointest Endosc 1998; 48:1.
  7. Kochar B, Akshintala VS, Afghani E, Elmunzer BJ, Kim KJ, Lennon AM, et al. Incidence, severity, and mortality of post-ERCP pancreatitis: a systematic review by using randomized, controlled trials. Gastrointest Endosc 2015; 81:143.
  8. Williams EJ, Taylor S, Fairclough P, Hamlyn A, Logan RF, Martin D, et al. Risk factors for complication following ERCP; results of a large-scale, prospective multicenter study. Endoscopy 2007; 39:793.
  9. Wang P, Li ZS, Liu F, Ren X, Lu NH, Fan ZN, et al. Risk factors for ERCP-related complications: a prospective multicenter study. Am J Gastroenterol 2009; 104:31.
  10. Andriulli A, Loperfido S, Napolitano G, Niro G, Valvano MR, Spirito F, et al. Incidence rates of post-ERCP complications: a systematic survey of prospective studies. Am J Gastroenterol 2007; 102:1781.
  11. Johnson GK, Geenen JE, Bedford RA, Johanson J, Cass O, Sherman S, et al. A comparison of nonionic versus ionic contrast media: results of a prospective, multicenter study. Midwest Pancreaticobiliary Study Group. Gastrointest Endosc 1995; 42:312.
  12. Halme L, Doepel M, von Numers H, Edgren J, Ahonen J. Complications of diagnostic and therapeutic ERCP. Ann Chir Gynaecol 1999; 88:127.
  13. Freeman ML, Nelson DB, Sherman S, Haber GB, Fennerty MB, DiSario JA, et al. Same-day discharge after endoscopic biliary sphincterotomy: observations from a prospective multicenter complication study. The Multicenter Endoscopic Sphincterotomy (MESH) Study Group. Gastrointest Endosc 1999; 49:580.
  14. Ho KY, Montes H, Sossenheimer MJ, Tham TC, Ruymann F, Van Dam J, et al. Features that may predict hospital admission following outpatient therapeutic ERCP. Gastrointest Endosc 1999; 49:587.
  15. Freeman ML, Nelson DB, Sherman S, Haber GB, Herman ME, Dorsher PJ, et al. Complications of endoscopic biliary sphincterotomy. N Engl J Med 1996; 335:909.
  16. Masci E,Mariani A,Curioni S,Testoni PA. Risk factors for pancreatitis following endoscopic retrograde cholangio-pancreatography: a meta-analysis. Endoscopy 2003; 35: 830–4.
  17. Mehta SN, Pavone E, Barkun JS, Bouchard S, Barkun AN. Predictors of post-ERCP complications in patients with choledocholithiasis. Endoscopy 1998; 30: 457 – 63.
  18. Aronson N, Flamm CR, Bohn RL, Mark DH, Speroff T. Evidence-based assessment: patient, procedure, or operator factors associated with ERCP complications. Gastrointest Endosc 2002; 56 (Suppl): S294 – 302.
  19. Cheng CL, Sherman S, Watkins JL, Barnett J, Freeman M, Geenen J et al. Risk factors for post-ERCP pancreatitis: a prospective multicenter study. Am J Gastroenterol 2006; 101: 139 – 47.
  20. Rabenstein T, Schneider HT, Nicklas M, Ruppert T, Katalinic A, Hahn EG, et al. İmpact of skill and experience of the endoscopist on the outcome of endoscopic sphincterotomy. Gastrointest Endosc 1999; 50: 628 – 36.
  21. Zhang Y, Wu W, Dong L, Yang C, Fan P, Wu H. Neutrophil to lymphocyte ratio predicts persistent organ failure and in-hospital mortality in an Asian Chinese population of acute pancreatitis. Medicine (Baltimore). 2016 Sep;95(37):e4746.
  22. Li Y, Zhao Y, Feng L, Guo R. Comparison of the prognostic values of inflammation markers in patients with acute pancreatitis: a retrospective cohort study. BMJ Open. 2017 Mar 27;7(3):e013206.
  23. Jeon TJ, Park JY. Clinical significance of the neutrophil-lymphocyte ratio as an early predictive marker for adverse outcomes in patients with acute pancreatitis. World J Gastroenterol. 2017 Jun 7;23(21):3883-3889.
  24. Rodrigues-Pinto E, Macedo G, Baron TH. ERCP competence assessment: miles to go before standardization. Endosc Int Open 2017; 5: E718-E721.
  25. Mine T, Morizane T, Kawaguchi Y,, Akashi R, Hanada K, Ito T, et al. Clinical practice guideline for post-ERCP pancreatitis. J Gastroenterol 2017 Jun 26. doi: 10.1007/s00535-017- 1359-5. [Epub ahead of print].
  26. Wang AY. Medications and methods for the prevention of Post-ERCP pancreatitis. GastroenterolHepatol (N Y) 2017; 13: 188-191.
  27. Masci E,Mariani A,Curioni S,Testoni PA. Risk factors for pancreatitis following endoscopic retrograde cholangio-pancreatography: a meta-analysis. Endoscopy 2003; 35: 830–4.
  28. Mehta SN, Pavone E, Barkun JS, Bouchard S, Barkun AN. Predictors of post-ERCP complications in patients with choledocholithiasis. Endoscopy 1998; 30: 457 – 63.
  29. Aronson N, Flamm CR, Bohn RL, Mark DH, Speroff T. Evidence-based assessment: patient, procedure, or operator factors associated with ERCP complications. Gastrointest Endosc 2002; 56 (Suppl): S294 – 302.
  30. Cheng CL, Sherman S, Watkins JL, Barnett J, Freeman M, Geenen J et al. Risk factors for post-ERCP pancreatitis: a prospective multicenter study. Am J Gastroenterol 2006; 101: 139 – 47.
  31. Rabenstein T, Schneider HT, Nicklas M, Ruppert T, Katalinic A, Hahn EG, et al. İmpact of skill and experience of the endoscopist on the outcome of endoscopic sphincterotomy. Gastrointest Endosc 1999; 50: 628 – 36.