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Dergiler / EMU Journal of Pharmaceutical Sciences / 2026 / Volume: 9 Issue: 1

Microbiological Assessment of Staphylococcus aureus Nasal Colonization and Antibiotic Resistance Patterns According to Nasal Septal Deviation Types

Barış Ali Ömer(EASTERN MEDITARRANEAN UNIVERSITY, SCHOOL OF MEDICINE)0009-0006-7145-3199
Ekin Ceylanlı(EASTERN MEDITARRANEAN UNIVERSITY, SCHOOL OF MEDICINE)0009-0000-4078-352X
Dilara Kuşi(EASTERN MEDITARRANEAN UNIVERSITY, SCHOOL OF MEDICINE)0009-0001-9247-2376
Laden Tepetmez(EASTERN MEDITARRANEAN UNIVERSITY, SCHOOL OF MEDICINE)0009-0003-7702-7850
Muharrem İyican(EASTERN MEDITARRANEAN UNIVERSITY, SCHOOL OF MEDICINE)0009-0007-3965-4190
Kadir Çakıral(DOĞU AKDENİZ ÜNİVERSİTESİ)0000-0003-4639-7528
Mümtaz Güran(EASTERN MEDITARRANEAN UNIVERSITY, SCHOOL OF MEDICINE)0000-0002-1536-8831
Didem Rıfkı(Department of Head and Neck Surgery, Famagusta State Hospital)0000-0003-2928-3158
Sayfa
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Yayın Tarihi
2026-05-21
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Preoperative screening protocols should incorporate comprehensive risk assessments beyond anatomical classification alone.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Nasal septal deviation (NSD) may facilitate bacterial colonization by impairing airflow.
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Temel Bulgular & Veri:We further sought to determine if specific clinical comorbidities and environmental exposures serve as independent catalysts for staphylococcal niche colonization.A multicenter prospective observational study was conducted (November 2023–June 2024) in Northern Cyprus. 105 patients with NSD underwent endoscopic examination and were classified using Mladina’s system.
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Sonuç & Katkı:Preoperative screening protocols should incorporate comprehensive risk assessments beyond anatomical classification alone.
🔬Tür:Research Article
📍Kapsam:2023 Verileri
⚙️Değişkenler:Mladina classification · MRSA · MSSA

Abstract

Nasal septal deviation (NSD) may facilitate bacterial colonization by impairing airflow. The relationship between specific anatomical types (Mladina classification) and Staphylococcus aureus colonization, including methicillin-resistant (MRSA) strains remains unclear. This study aims to evaluate the prevalence and antibiotic susceptibility profiles of Staphylococcus aureus, within the altered microenvironments created by different Mladina-classified nasal septal deviations (NSD). We further sought to determine if specific clinical comorbidities and environmental exposures serve as independent catalysts for staphylococcal niche colonization.A multicenter prospective observational study was conducted (November 2023–June 2024) in Northern Cyprus. 105 patients with NSD underwent endoscopic examination and were classified using Mladina’s system. Nasal swabs were cultured, and antibiotic susceptibility was determined via EUCAST guidelines.MRSA colonization was detected in 21.0% of patients. Although colonization rates varied across Mladina types (7.7%–29.4%), no statistically significant association was found (p>0.05). Chronic sinusitis, allergic rhinitis, and smoking showed numerically higher MRSA rates but lacked statistical significance.Mladina’s NSD classification does not independently predict MRSA colonization risk. Preoperative screening protocols should incorporate comprehensive risk assessments beyond anatomical classification alone.

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Bu Makaleye Atıf Yap

Ömer, B. A., Ceylanlı, E., Kuşi, D., Tepetmez, L., İyican, M., Çakıral, K., Güran, M., Rıfkı, D. (2026). Microbiological Assessment of Staphylococcus aureus Nasal Colonization and Antibiotic Resistance Patterns According to Nasal Septal Deviation Types. EMU Journal of Pharmaceutical Sciences, Volume: 9 Issue: 1. https://doi.org/10.54994/emujpharmsci.1839816

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