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Dergiler / Eastern Journal of Medicine / 2020 / Cilt: 25 - Sayı: 1

The Investigation of Prenatal Screening Test Parameters in Predicting HELLP Syndrome

Buğra ÇOŞKUN
Selçuk ERKİLİNÇ
Özgür KARA
Bora ÇOŞKUN
Burak ELMAS
Dilek ŞAHİN
Sayfa
114–117
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Low PAPP-A levels and high second trimester B hCG levels may be associated with HELLP syndrome in subsequent gestational weeks.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:We aimed to investigate whether first and second-trimester prenatal screening test parameters may be useful in predicting HELLP Syndrome.
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Temel Bulgular & Veri:The collected data were as follows; age, gravida, parity, body mass index, gestational week at labor, route of delivery, birth weight, aspartate aminotransferase (AST), Lactate dehydrogenase (LDH), bilirubin, first trimester multiple of medians (MOM) of pregnancy-associated plasma protein-A (PAPP-A) and Beta human chorionic gonadotropin (B hCG), second trimester B hCG, unconjugated estriol (uE3) and AFP levels were measured.
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Sonuç & Katkı:Low PAPP-A levels and high second trimester B hCG levels may be associated with HELLP syndrome in subsequent gestational weeks.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

We aimed to investigate whether first and second-trimester prenatal screening test parameters may be useful in predicting HELLP Syndrome. HELLP syndrome was defined according to Sibai criteria. The collected data were as follows; age, gravida, parity, body mass index, gestational week at labor, route of delivery, birth weight, aspartate aminotransferase (AST), Lactate dehydrogenase (LDH), bilirubin, first trimester multiple of medians (MOM) of pregnancy-associated plasma protein-A (PAPP-A) and Beta human chorionic gonadotropin (B hCG), second trimester B hCG, unconjugated estriol (uE3) and AFP levels were measured. A total of 80 patients in the study group and 135 patients in control groups were included in the study. All the markers of HELLP syndrome were significantly higher in the study group due to the markers was the criteria for HELLP syndrome. While first-trimester PAPP-A was significantly lower in the study group, B hCG levels were similar between groups. The second trimester B hCG level was significantly higher in the study group. AFP level and uE3 level were not different in the control and study groups. Low PAPP-A levels and high second trimester B hCG levels may be associated with HELLP syndrome in subsequent gestational weeks.

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Bu Makaleye Atıf Yap

ÇOŞKUN, B., ERKİLİNÇ, S., KARA, Ö., ÇOŞKUN, B., ELMAS, B., ŞAHİN, D. (2020). The Investigation of Prenatal Screening Test Parameters in Predicting HELLP Syndrome. Eastern Journal of Medicine, Cilt: 25 - Sayı: 1, 114–117. https://ajindex.com/articles/156659

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Kaynakça (12)

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