Dergiler / Turkish Journal of Internal Medicine / 2026 / Volume: 8

The Relationship Between Disease Awareness and Treatment Adherence in Patients with Diabetes: A Single-Center Study

Elifnur Avcı(RECEP TAYYIP ERDOGAN UNIVERSITY)0000-0001-8510-9483
Teslime Ayaz(IZMIR BAKIRCAY UNIVERSITY)0000-0002-3468-1428
Kamil Konur(RECEP TAYYIP ERDOGAN UNIVERSITY)0000-0002-9666-8085
Sayfa
—
Yayın Tarihi
2026-03-10
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Additionally, the proportion of patients with high adherence was significantly greater among those receiving oral antidiabetic therapy alone compared to those receiving combined insulin and oral antidiabetic treatment.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objective: Diabetes mellitus is a chronic metabolic disease requiring long-term lifestyle modification and medical treatment.
📊
Temel Bulgular & Veri:Inadequate disease management may lead to serious acute and chronic complications, increased morbidity, and reduced quality of life.
💡
Sonuç & Katkı:Additionally, the proportion of patients with high adherence was significantly greater among those receiving oral antidiabetic therapy alone compared to those receiving combined insulin and oral antidiabetic treatment.
🔬Tür:Uygulamalı Anket & Alan Araştırması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Type 2 diabetes mellitus · Morisky-8 · Treatment adherence

Abstract

Objective: Diabetes mellitus is a chronic metabolic disease requiring long-term lifestyle modification and medical treatment. Inadequate disease management may lead to serious acute and chronic complications, increased morbidity, and reduced quality of life. Treatment adherence in diabetes is a multifactorial process influenced by pharmacological regimens, disease awareness, education level, and sociodemographic characteristics. Previous studies have shown that insufficient knowledge about the disease and low awareness are associated with poor glycemic control and accelerated disease progression. Given the lifelong nature of diabetes treatment, difficulties in disease acceptance and sustaining treatment adherence are common. Understanding how patients’ awareness, education, and self-perceived knowledge relate to treatment adherence and laboratory outcomes may explain poor glycemic control. Therefore, this study aimed to evaluate the relationship between treatment adherence, disease awareness, and disease progression by analyzing questionnaire data and laboratory findings of patients admitted to Recep Tayyip Erdoğan University Training and Research Hospital. Methods: This study was conducted using a questionnaire-based survey administered to 500 patients diagnosed with type 2 diabetes mellitus for at least three months who attended Recep Tayyip Erdoğan University Training and Research Hospital. Results: Of the 500 diabetic patients included in the study, 284 (56.8%) were female and 216 (43.2%) were male. The mean age of the participants was 59.7 ± 13.1 years. The mean HbA1c level was 7.7 ±1.59, while the mean Morisky adherence score was 5.4 ± 1.7. Low adherence was observed in 259 patients (51.8%), moderate adherence in 172 patients (34.4%), and high adherence in 69 patients (13.8%). A statistically significant difference was found between Morisky adherence categories and HbA1c levels (p < 0.001). HbA1c levels were highest among patients with low adherence and lowest among those with high adherence. Conclusion: HbA1c levels were significantly higher in patients with low Morisky adherence scores, whereas the lowest HbA1c levels were observed in patients with high adherence. Additionally, the proportion of patients with high adherence was significantly greater among those receiving oral antidiabetic therapy alone compared to those receiving combined insulin and oral antidiabetic treatment.

🔖

Bu Makaleye Atıf Yap

Avcı, E., Ayaz, T., Konur, K. (2026). The Relationship Between Disease Awareness and Treatment Adherence in Patients with Diabetes: A Single-Center Study. Turkish Journal of Internal Medicine, Volume: 8. https://doi.org/10.46310/tjim.1866507

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (19)

  1. Colberg SR, Sigal RJ, Yardley JE, Riddell MC, Dunstan DW, Dempsey PC, et al. Physical activity/exercise and diabetes: a position statement of the American Diabetes Association. Diabetes Care. 2016;39(11):2065-79. doi:10.2337/dc16-1728.
  2. Evert AB, Boucher JL, Cypress M, Dunbar SA, Franz MJ, Mayer-Davis EJ, et al. Nutrition therapy recommendations for the management of adults with diabetes. Diabetes Care. 2013;36(11):3821-42. doi:10.2337/dc13-2042.
  3. American Diabetes Association Professional Practice Committee. 2. Classification and diagnosis of diabetes: standards of medical care in diabetes-2022. Diabetes Care. 2022;45(Suppl 1):S17-38. doi:10.2337/dc22-S002.
  4. Sayiner ZA, Savas E, Kul S, Morisky DE. Validity and reliability of the Turkish version of the 8-item morisky medication adherence scale in patients with type 2 diabetes. Eur J Ther. 2020;26(1):47-52. doi:10.5152/ eurjther.2020.19132.
  5. Shigaki CL, Kruse RL, Mehr DR, Ge B. The REALM vs. NVS: a comparison of health literacy measures in patients with diabetes. Ann Behav Sci Med Educ. 2012;18(1):9-13. doi:10.1007/bf03355174.
  6. Peyrot M, Rubin RR, Kruger DF, Travis LB. Correlates of insulin injection omission. Diabetes Care. 2010;33(2):240-5. doi:10.2337/dc09-1348.
  7. Kara AM, Kara T. Relationship of treatment method with medication adherence, quality of life and depression in patients diagnosed with type 2 diabetes. Med Bull Haseki. 2019;57(4):377-85. doi:10.4274/haseki.galenos.2019.4874.
  8. Jannoo Z, Mamode Khan N. Medication adherence and diabetes self-care activities among patients with type 2 diabetes mellitus. Value Health Reg Issues. 2019;18:30-5. doi:10.1016/j.vhri.2018.06.003.
  9. Osei-Yeboah J, Lokpo SY, Owiredu WKBA, Johnson BB, Orish VN, Botchway F, et al. Medication adherence and its association with glycaemic control, blood pressure control, glycosuria and proteinuria among people living with diabetes in the Ho Municipality, Ghana. Open Public Health J. 2018;11:552-61. doi:10.2174/187494450 1811010552.
  10. Chew BH, Hassan NH, Sherina MS. Determinants of medication adherence among adults with type 2 diabetes mellitus in three Malaysian public health clinics: a cross-sectional study. Patient Prefer Adherence. 2015;9:639-48. doi:10.2147/PPA.S81612.
  11. Aloudah NM, Scott NW, Aljadhey HS, Araujo-Soares V, Alrubeaan KA, Watson MC. Medication adherence among patients with type 2 diabetes: a mixed methods study. PLoS One. 2018;13(12):e0207583. doi:10.1371/ journal.pone.0207583.
  12. Sweileh WM, Zyoud SH, Abu Nab’A RJ, Deleq MI, Enaia MI, Nassar SM, et al. Influence of patients’ disease knowledge and beliefs about medicines on medication adherence: findings from a cross-sectional survey among patients with type 2 diabetes mellitus in Palestine. BMC Public Health. 2014;14:94. doi:10.1186/1471-2458-14-94.
  13. Lee WY, Ahn J, Kim JH, Hong YP, Hong SK, Kim YT, et al. Reliability and validity of a self-reported measure of medication adherence in patients with type 2 diabetes mellitus in Korea. J Int Med Res. 2013;41(4):1098-110. doi:10.1177/0300060513484433.
  14. Arulmozhi S, Mahalakshmy T. Self care and medication adherence among type 2 diabetics in Puducherry, Southern India: a hospital based study. J Clin Diagn Res. 2014;8(4):UC01-3. doi:10.7860/JCDR/2014/7732.4256.
  15. Fadare J, Olamoyegun M, Gbadegesin BA. Medication adherence and direct treatment cost among diabetes patients attending a tertiary healthcare facility in Ogbomosho, Nigeria. Malawi Med J. 2015;27(2):65-70. doi:10.4314/mmj.v27i2.7.
  16. Wong MCS, Wu CHM, Wang HHX, Li HW, Hui EMT, Lam AT, et al. Association between the 8-item Morisky medication adherence scale (MMAS-8) score and glycaemic control among Chinese diabetes patients. J Clin Pharmacol. 2015;55(3):279-87. doi:10.1002/jcph.408.
  17. Küçük E, Yapar K. Health perception, health-related behaviors, and medication adherence of patients with Type II Diabetes: a study in the Black Sea Region of Turkey. TAF Prev Med Bull. 2016;15(4):285-91. doi:10.5455/ pmb.1-1446795532.
  18. Dibonaventura M, Wintfeld N, Huang J, Goren A. The association between nonadherence and glycated hemoglobin among type 2 diabetes patients using basal insulin analogs. Patient Prefer Adherence. 2014;8:873-82. doi:10.2147/PPA.S55550.
  19. Mirahmadizadeh A, Khorshidsavar H, Seif M, Sharifi MH. Adherence to medication, diet and physical activity and the associated factors amongst patients with type 2 diabetes. Diabetes Ther. 2020;11:479-94. doi:10.1007/ s13300-019-00750-8.