KaydedilenlerDerginizi ekleyin

Dergiler / Turkish Journal of Bioscience and Collections / 2026 / Volume: 9 Issue: 1

Antimicrobial Activity of Essential Oils for Potential Use as Wound Dressing Material Additives

Beyza Karakuş(İstanbul University, Faculty of Science, TEBIP Programme)0009-0002-9831-443X
Nazmiye Özlem Şanlı(İstanbul University, Faculty of Science, Department of Biology, Section of Biotechnology)0000-0001-8969-5125
Sayfa
—
Yayın Tarihi
2025-03-14
🏛️Bu makalenin bibliyografik verileri ve tam metin bağlantısı DergiPark üzerinden sağlanmıştır.
DergiPark Kaydı ↗
✨

Yapay Zeka Hızlı Bakış & Çıkarımlar

AI Insight
⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In conclusion, based on the results of our study, wound dressings with natural essential oils used to reduce the risk of infection and indirectly promote wound healing can reduce healing time and improve patient quality of life in a cost,effective care setting.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Objective: The use of natural products in wound care has a long history, with herbal extracts and aromatic oils offering therapeutic benefits such as antimicrobial and antioxidant properties.
📊
Temel Bulgular & Veri:This study investigated the antimi, crobial efficacy of essential oils (tea tree, thyme, and cinnamon) incorporated into non,woven, hypoallergenic, and sterile wound dressings.
💡
Sonuç & Katkı:In conclusion, based on the results of our study, wound dressings with natural essential oils used to reduce the risk of infection and indirectly promote wound healing can reduce healing time and improve patient quality of life in a cost,effective care setting.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Aromatic oils · Bioactive compounds · Infection control

Abstract

Objective: The use of natural products in wound care has a long history, with herbal extracts and aromatic oils offering therapeutic benefits such as antimicrobial and antioxidant properties. This study investigated the antimi, crobial efficacy of essential oils (tea tree, thyme, and cinnamon) incorporated into non,woven, hypoallergenic, and sterile wound dressings. Materials and Methods: The antimicrobial activity of tea tree, thyme, and cinnamon oils was evaluated using minimum inhibitory concentration (MIC) and minimum bactericidal/fungicidal concentration (MBC/MFC) tests. After application of the MBC doses determined in our study to the wound dressing and gauze, the samples were evaluated using a stepwise qualitative to quantitative experimental design to assess the static and cidal effects. Results: Tea tree oil showed the highest MIC/MBC values (1,3 mg/mL), while thyme and cinnamon oils showed efficacy at lower concentrations (0.25 mg/mL) against Staphylococcus aureus and Escherichia coli. In addition, the essential oils showed significant antifungal activity against Candida albicans at lower concentrations than bacteria. The impregnated dressings exhibited strong antimicrobial properties with a 99.99% (4 log) reduction in microbial growth, confirming the potential of essential oils as viable, biocompatible alternatives to traditional chemical agents in wound healing applications. Conclusion: These findings highlight the benefits of natural essential oils in improving wound care while minimising the risk of toxicity and resistance associated with chemical treatments. In conclusion, based on the results of our study, wound dressings with natural essential oils used to reduce the risk of infection and indirectly promote wound healing can reduce healing time and improve patient quality of life in a cost,effective care setting.

🔖

Bu Makaleye Atıf Yap

Karakuş, B., Şanlı, N. Ö. (2025). Antimicrobial Activity of Essential Oils for Potential Use as Wound Dressing Material Additives. Turkish Journal of Bioscience and Collections, Volume: 9 Issue: 1. https://doi.org/10.26650/tjbc.1624479

📄 Tam Metin PDF Okuyucu

📄

PDF görüntüleyici hazırlanıyor...

Kaynakça (45)

  1. AATCC TM100-2019 (2019). Test Method for Antlbacterlal Flnlshes on Textlle Materials: Assessment of American Association of Textile Chemists and Colorlsts: Durham, NC, USA. google scholar
  2. AATCC 147:2004 (2004). Antimicrobial Activity Assessment of Textile Mate-rials: Parallel Streak Method from American Association of Textile Chemists and Colorists. google scholar
  3. Akpınar, R., Yıldırım Baştemur, G., Bıçak, B., Sanli, N. O., Mertoğlu Kamalı, E., Pekmez, M.,. & Perçin Özkorucuklu, S. (2024). PhyTochemical profiling, in vitro biological activities, and in silico (molecular Docking and absorption, Distribution, metabolism, excretion, toxi-city) studies of Polygonum cognatum Meissn. Journal of Separatlon Sclence, 47(1), 2300750. google scholar
  4. Andrews, R. E., Parks, L. W. & Spence, K. D. (1980). Some effects of Douglas fir terpenes on certain microorganisms. Applled and Envlronmental Mlcroblology, 40, 301-304. google scholar
  5. Aydoğdu, E. Ö. A., Kesiktaş, M., Sanli, N. O., Güngör, N. D., Sancar, S., Yildiz, T. & Yemişken, E. (2023). Preliminary study on antimicrobial activities of skin mucus from by-catch of species. Oceanologlcal and Hydroblologlcal Studles, 52(2), 137-146. google scholar
  6. Bauer, K. D., Garbe, H. & Surburg, H. (1997). Common fragrance and flavor Materials. Weinheim, Germany: Wiley-VCH Verlag. google scholar
  7. Behary, N., Smet, D. D., Campagne, C. & Vanneste, M. J. (2020). Antibac-terial and multifunctional polyester textile using plant-baseD cinnamaldehyde. Journal of Textlle Sclence & Fashlon Technology, 4, 202. https://doi.org/10.33552/JTSFT.2020.04.000597 google scholar
  8. Besen, B. S. (2019). Production of disposable antibacterial textiles via Application of tea tree oil encapsulateD into Different wall Materials. Flbers PolyM., 20, 2587-2593. https://doi.org/l0.1007/s12221-019-9350-9 google scholar
  9. Borda, L. J., Macquhae, F. E. & Kirsner, R. S. (2016). Wound dressings: a comprehensive review. Current Dermatology Reports, 5, 287-297. google scholar
  10. Borugâ, O., Jianu, C., Mişcâ, C., GoleÇ, I., Gruia, A. T. & Horhat, F. G. (2014). Thymus vulgarls essential oil: Chemical composition and antimi-crobial activity. Journal of Medlclne and Llfe, 7 (Spec Iss 3), 56. google scholar
  11. CLSI (2015). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically; Approved Standard. 10th edition. CLSI document M07-A10. Wayne, PA: Clinical and Laboratory Stan-dards Institute. google scholar
  12. Costa, G. M., Prado, I. A., de Carvalho-Castro, G. D. A., Mian, G. F., Leite, C. A. L., Custodio, D. A. C. & Piccoli, R. H. (2021). Minimum inhibitory concentration of essential oils against Staphylococcus aureus iso-lated from dogs with external otitis. Semina: Ciencias Agrârias, 42 (6SUPL2), 3837-3854. google scholar
  13. Cremar, L., Gutierrez, J., Martinez, J., Materon, L., Gilkerson, R., Xu, F. & Lozano, K. (2018). Development of antimicrobial chitosan based nanofiber dressings for wound healing Applications. Nanomedi-cine Journal, 5, 6-14. google scholar
  14. Çitil, M. U., Mete, E., Oğuz, E. O., Mete, G. A., Şahin, B. & Kaleli, İ. (2015). Deneysel Staphylococcus aureus yumuşak doku enfeksiyonlarında ibuprofenin yara iyileşmesi üzerindeki etkisinin araştırılması. Mikrobiyoloji Bülteni, 49(2), 166-180. google scholar
  15. de Bouchberg, M.S., Allegrini, J., Bessiere, C., Attisto, M., Passet, J. & Granger, R. (1976). Proprietes microbiologiques des huiles essen-tielles de chimotypes de Thymus vulgaris Linnnaeus. Rivista Italiana Essenze Profumi Piante Officinati Aromi Saponi Cosmetici, 58, 527-536. google scholar
  16. DIN EN ISO 20645: Textile fabrics—determination of antibacterial activity —agar diffusion plate test. google scholar
  17. Dumville J. C., Soares M. O., O’Meara S. &Cullum, N. (2012). Systematic review and mixed treatment comparison: dressing to heal diabetic foot ulcers. Diabetologia, 55, 1902-10. google scholar
  18. Erdem, A. K. & Yurudu, N. S. (2008). The evaluation of antibacterial activity of fabrics impregnated with dimethyltetradecyl (3-(trimethoxysi-lyl) propyl) ammonium chloride. European Journal of Biology, 67(2), 115-122. google scholar
  19. Gao, F., Zhou, H., Shen, Z., Zhu, G., Hao, L., Chen, H.,. & Zhou, X. (2020). Long-lasting anti-bacterial activity and bacteriostatic mechanism of tea tree oil adsorbed on the amino-functionalized mesoporous silica-coated by PAA. Colloids and Surfaces B: Biointerfaces, 188, 110784. google scholar
  20. Gheorghita, D., Grosu, E., Robu, A., Ditu, L. M., Deleanu, I. M., Gradisteanu Pircalabioru, G.,. & Antoniac, V. I. (2022). Essential oils as antimi-crobial active substances in wound dressings. Materials, 15(19), 6923. google scholar
  21. Koire, İ. İ., Menceloğlu, Y. Z., & Şanlı, N. Ö. (2024). Antibacterial efficiency of quaternary ammonium silane-coated shoe insoles using the Sol-Gel Technique. Turkish Journal of Bioscience and Collections, 8 (2), 111-119. google scholar
  22. Lopez, P., Sanchez, C., Batlle, R. & Nerin, C. (2005). Solid- and vapor-phase antimicrobial activities of six essential oils: Susceptibility of selected foodborne bacterial and fungal strains. Journal of Agri-cultural and Food Chemistry, 53, 6939-6946. google scholar
  23. Nychas, G. J. E., Tassou, C. C. & Skandamis, P. (2003). Antimicrobials from herbs and spices. In S. m. Roller (Ed.), Natural antimicrobials for the minimal processing of foods (pp. 176-200). New York: CRC Press, Woodhead Publishers google scholar
  24. Oberoi, J. K., Wattal, C., Goel, N., Raveendran, R., Datta, S. & Prasad, K. (2012). Non-albicans Candida species in blood stream infections in a tertiary care hospital at New Delhi, India. Indian Journal of Medical Research, 136, 997-1003. google scholar
  25. Punjataewakupt, A., Napavichayanun, S. & Aramwit, P. (2019). The down-side of antimicrobial agents for wound healing. European Journal of Clinical Microbiology & Infectious Diseases, 38, 39-54. google scholar
  26. Raharivelomanana, P. J., Terrom, G. P., Bianchini, J. P. & Coulanges, P. (1989). Study of the antimicrobial action of various essential oils extracted from Malagasy plants. II: Lauraceae. Archives de l'lnstitut Pasteur de Madagascar, 56, 261-271. (in France) google scholar
  27. Rieger, K. A. & Schiffman, J. D. (2014). Electrospinning an essential oil: Cinnamaldehyde enhances the antimicrobial efficacy of chitosan/ poly(ethylene oxide) nanofibers. Carbohydrate Polymers, 113, 561568. google scholar
  28. Sanglard, D. (2016). Emerging threats in antifungal-resistant fungal pathogens. Frontiers in Medicine, 3, 11-13. google scholar
  29. Seow, Y. X., Yeo, C. R., Chung, H. L. & Yuk, H. G. (2014). Plant essential oils as active antimicrobial agents. Critical Reviews in Food Science and Nutrition, 54(5), 625-644. google scholar
  30. Shi, C., Zhao, X., Yan, H., Meng, R., Zhang, Y., Li, W.,. & Guo, N. (2016). Effect of tea tree oil on Staphylococcus aureus growth and enterotoxin production. Food Control, 62, 257-263. google scholar
  31. Sikkema, J., de Bont, J. A. M. & Poolman, B. (1995). Mechanisms of membrane toxicity of hydrocarbons. Microbiological Reviews, 59, 201-222. google scholar
  32. Simöes, D., Miguel, S. P., Ribeiro, M. P., Coutinho, P., Mendonça, A. G. & Cor-reia, I. J. (2018). Recent advances on antimicrobial wound dressing: A review. European Journal of Pharmaceutics and Biopharmaceu-tics, 127, 130-141. google scholar
  33. Thiruvoth, F. M., Mohapatra, D. P., Kumar, D., Chittoria, S. R. K. & Nand-hagopal, V. (2015). Current concepts in the physiology of adult wound healing. Plastic and Aesthetic Research, 2, 250-256. google scholar
  34. Toroğlu, S. & Çenet, M. (2006). Tedavi amaçlı kullanılan bazı bitkilerin kullanım alanları ve antimikrobiyal aktivitelerinin belirlenmesi için kullanılan metodlar. KSÜ Fen ve Mühendislik Dergisi, 9(2), 12-20. google scholar
  35. Tüfekyapan, T., Bastemur, G. Y., Bıçak, B., Akpinar, R., Sanli, N. O., Gündüz, S. K.,. & Karipcin, F. (2025). Syntheses of new ternary complexes with 1-benzoyl-3-(benzimidazoyl) thiourea) and amino acids: Ex-perimental, theoretical, electrochemical, antioxidant, antibacter-ial, and molecular docking studies. Inorganic Chemistry Communi-cations, 113859. https://doi.org/10.1016/j.inoche.2024.113859 google scholar
  36. Türsen, Ü. (2013). Ülser tedavisinde yara örtüleri. Turkish Journal of Der-matology, 7, 61-71. google scholar
  37. Uribe, S., Ramirez, J. & Pena, A. (1985). Effects of Ş-pinene on yeast membrane functions. Journal of Bacteriology, 161, 1195-1200. google scholar
  38. Vasconcelos, N. G., Croda, J. & Simionatto, S. (2018). Antibacterial mech-anisms of cinnamon and its constituents: A review. Microbial Pathogenesis, 120, 198-203. google scholar
  39. Yasin, M., Younis, A., Javed, T., Akram, A., Ahsan, M., Shabbir, R.,. & El-Esawi, M. A. (2021). River tea tree oil: composition, antimicrobial and antioxidant activities, and potential Applications in agricul-ture. Plants, 10(10), 2105. google scholar
  40. Akpınar, R., Yıldırım Baştemur, G., Bıçak, B., Sanli, N. O., Mertoğlu Kamalı, E., Pekmez, M.,. & Perçin Özkorucuklu, S. (2024). PhyTochemical profiling, in vitro biological activities, and in silico (molecular Docking and absorption, Distribution, metabolism, excretion, toxi-city) studies of Polygonum cognatum Meissn. Journal of Separatlon Sclence, 47(1), 2300750. google scholar
  41. Gao, F., Zhou, H., Shen, Z., Zhu, G., Hao, L., Chen, H.,. & Zhou, X. (2020). Long-lasting anti-bacterial activity and bacteriostatic mechanism of tea tree oil adsorbed on the amino-functionalized mesoporous silica-coated by PAA. Colloids and Surfaces B: Biointerfaces, 188, 110784. google scholar
  42. Gheorghita, D., Grosu, E., Robu, A., Ditu, L. M., Deleanu, I. M., Gradisteanu Pircalabioru, G.,. & Antoniac, V. I. (2022). Essential oils as antimi-crobial active substances in wound dressings. Materials, 15(19), 6923. google scholar
  43. Shi, C., Zhao, X., Yan, H., Meng, R., Zhang, Y., Li, W.,. & Guo, N. (2016). Effect of tea tree oil on Staphylococcus aureus growth and enterotoxin production. Food Control, 62, 257-263. google scholar
  44. Tüfekyapan, T., Bastemur, G. Y., Bıçak, B., Akpinar, R., Sanli, N. O., Gündüz, S. K.,. & Karipcin, F. (2025). Syntheses of new ternary complexes with 1-benzoyl-3-(benzimidazoyl) thiourea) and amino acids: Ex-perimental, theoretical, electrochemical, antioxidant, antibacter-ial, and molecular docking studies. Inorganic Chemistry Communi-cations, 113859. https://doi.org/10.1016/j.inoche.2024.113859 google scholar
  45. Yasin, M., Younis, A., Javed, T., Akram, A., Ahsan, M., Shabbir, R.,. & El-Esawi, M. A. (2021). River tea tree oil: composition, antimicrobial and antioxidant activities, and potential Applications in agricul-ture. Plants, 10(10), 2105. google scholar