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Dergiler / Pediatric Practice and Research / 2026 / Volume: 7 Issue: Ek

Phenytoin Induced Anaphylaxis: a Case Report Fenitoin İlişkili Anaflaksi: Olgu Sunumu

Şule Ayas(Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Pediatri AD)
Kezban Öztürk(Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Pediatri AD, Pediatrik Nöroloji BD)
Mustafa Gençeli(Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Pediatri AD)
Hüseyin Çaksen(Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi, Pediatri AD, Pediatrik Nöroloji BD)
Sayfa
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Yayın Tarihi
2019-12-10
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

As well as the side effects such as phenytoin-induced Steven-Johnson syndrome, DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) and cerebellar toxicity, a rarely life-threatening anaphylaxis requiring urgent treatment can be seen.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Introduction: Phenytoin is an aromatic ring antiepileptic drug (AED) commonly used in epilepsy.
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Temel Bulgular & Veri:Introduction: Phenytoin is an aromatic ring antiepileptic drug (AED) commonly used in epilepsy.
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Sonuç & Katkı:As well as the side effects such as phenytoin-induced Steven-Johnson syndrome, DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) and cerebellar toxicity, a rarely life-threatening anaphylaxis requiring urgent treatment can be seen.
🔬Tür:Conference Paper
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Phenytoin · anaphylaxis · epilepsy

Abstract

Introduction: Phenytoin is an aromatic ring antiepileptic drug (AED) commonly used in epilepsy. As well as the side effects such as phenytoin-induced Steven-Johnson syndrome, DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) and cerebellar toxicity, a rarely life-threatening anaphylaxis requiring urgent treatment can be seen.

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Bu Makaleye Atıf Yap

Ayas, Ş., Öztürk, K., Gençeli, M., Çaksen, H. (2019). Phenytoin Induced Anaphylaxis: a Case Report Fenitoin İlişkili Anaflaksi: Olgu Sunumu. Pediatric Practice and Research, Volume: 7 Issue: Ek. https://ajindex.com/articles/1535257

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  1. References 1- Karimzadeh P, Bakrani V. Antiepileptic drug-related adverse reactions and factors influencing these reactions. Iran J Child Neurol 2013 Summer;7(3):25-9. 2- Yaari Y, Selzer ME, Pincus JH. Phenytoin: mechanisms of its anticonvulsant action. Ann Neurol 1986; 20:171. 3- Atanaskovic-Markovic M, Gomes E, Cernadas JR, et al. Diagnosis and management of drug-induced anaphylaxis in children: An EAACI position paper.Pediatr Allergy Immunol2019 May;30(3):269-276. 4- Grabenhenrich LB, Dölle S, Moneret-Vautrin A, et al. Anaphylaxis in children and adolescents: The European Anaphylaxis Registry.J Allergy Clin Immunol2016 Apr;137(4):1128-1137.e1. 5- Polat I, Karaoglu P, Ayanoglu M, Yis U, Hiz S. Life-Threatening and Rare Adverse Effects of Phenytoin.Pediatr Emerg Care2015 Jul;31(7):e3. 6- Amit D Bhatt, Anjalin Joshi, AP Jaın.Anaphylactic Shock: A Rare Presentation of PhenytoinDrug Reaction. Indian Journal of Clinical Practice 2013 May; Vol. 23, No. 12 7- Sampson HA, Muñoz-Furlong A, Campbell RL, et al. Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. J Allergy Clin Immunol 2006; 117:391. 8- Dhami S, Panesar SS, Roberts G, et al.Management of anaphylaxis: a systematic review.Allergy 2014 Feb;69(2):168-75. 9- Muraro A, Roberts G, Clark A, et al.The management of anaphylaxis in childhood: position paper of the European academy of allergology and clinical immunology.Allergy 2007 Aug;62(8):857-71.