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Dergiler / Medical Research Reports / 2026 / Volume: 8 Issue: 1

KAN EOZİNOFİL SEVİYELERİ İLE COVİD-19 MORTALİTESİ ARASINDAKİ İLİŞKİ

The Relationship Between Blood Eosinophil Levels and COVID-19 Mortality

Gökben Yaslı(İZMİR İL SAĞLIK MÜDÜRLÜĞÜ)0000-0003-2464-2238
Gülper Şener(Menemen Devlet Hastanesi)0009-0007-0121-6005
Ebru Turhan(IZMIR BAKIRCAY UNIVERSITY)0000-0003-2387-3253
Sayfa
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Yayın Tarihi
2025-03-24
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Bu göstergelerin COVID-19 hastalarındaki klinik önemini araştırmak için daha fazla araştırmaya ihtiyaç vardır.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Amaç: COVID-19, şiddetli akut solunum yolu sendromu SARS-COV-2’nin neden olduğu küresel bir pandemidir.
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Temel Bulgular & Veri:Bu çalışmanın amacı, kan eozinofil düzeyleri ile COVID-19'un şiddeti ve mortalitesi arasındaki ilişkiyi belirlemektir.
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Sonuç & Katkı:Bu göstergelerin COVID-19 hastalarındaki klinik önemini araştırmak için daha fazla araştırmaya ihtiyaç vardır.
🔬Tür:Uygulamalı Anket & Alan Araştırması
📍Kapsam:2020 · 678 hasta
⚙️Değişkenler:COVID-19 · Disease Severity · Eosinophils

Özet

Amaç: COVID-19, şiddetli akut solunum yolu sendromu SARS-COV-2’nin neden olduğu küresel bir pandemidir. Bu çalışmanın amacı, kan eozinofil düzeyleri ile COVID-19'un şiddeti ve mortalitesi arasındaki ilişkiyi belirlemektir. Yöntem: 678 hastanın verileri, Mart 2020 ile Aralık 2021 tarihleri arasında araştırmacılar tarafından bir hastanenin elektronik veri tabanından geriye dönük olarak toplandı. Bu tanımlayıcı bir çalışmadır ve özel bir örnekleme yöntemi kullanılmamıştır. Veriler, hastaların üç grubuna (orta, şiddetli ve kronik) dayanarak değerlendirildi. Hastaneye yatışı takip eden ilk 24 saat içinde alınan eozinofil değerleri elde edildi. Veriler, IBM SPSS Statistics (20.0) yazılımı kullanılarak analiz edildi. Normal dağılım varsayımlarının karşılandığı durumlarda parametrik testler kullanıldı. İki bağımsız grup için Mann-Whitney U testi ve ilişkileri belirlemek için çok değişkenli lojistik regresyon analizi kullanıldı. p değeri 0,05). MCHC'de azalma (OR: 0,996; p=0,007) ve sodyumda azalma (p=0,031) hastalık şiddeti üzerinde hafifletici bir etki göstermiştir. Diğer parametrelerin etkisi istatistiksel olarak anlamlı bulunmamıştır. Sonuç: Eozinofil düzeyinin COVID-19'un şiddeti ve mortalitesi üzerine etkisi bulunmamış olup, MCHC'de azalma ve sodyumda azalma hastalık şiddeti üzerinde hafifletici bir etki göstermiştir. Bu göstergelerin COVID-19 hastalarındaki klinik önemini araştırmak için daha fazla araştırmaya ihtiyaç vardır.

Abstract

Aim: COVID-19 is a global pandemic caused by severe acute respiratory syndrome (SARS-COV-2). The objective of this study is to determine the relationship between blood eosinophil levels and the severity and mortality of COVID-19. Methods: The data of 678 patients were retrospectively collected from the electronic database of a hospital by researchers between March 2020 and December 2021. This is a descriptive study, and no specific sampling method was employed. The data were evaluated based on three groups of patients (moderate, severe, and chronic). Eosinophil values within the first 24 hours following hospital admission were obtained. The data was analyzed through IBM SPSS Statistics (20.0) software. Parametric tests were used for the statistical evaluations when the normality assumptions were met. Mann-Whitney U was used for two independent groups and multivariate logistic regression analysis was used to identify the relations. p-value 0.05). A reduction in MCHC (OR: 0.996; p=0.007) and sodium (p=0.031) demonstrated a mitigating effect on disease severity. The predictive effect of other parameters was found to be statistically insignificant. Conclusion: The effect of eosinophil levels on the severity and mortality of COVID-19 has not been found, whereas a decrease in MCHC and sodium levels showed a mitigating effect on disease severity. Further research is needed to investigate the clinical significance of these indicators in COVID-19 patients.

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Bu Makaleye Atıf Yap

Yaslı, G., Şener, G., Turhan, E. (2025). KAN EOZİNOFİL SEVİYELERİ İLE COVİD-19 MORTALİTESİ ARASINDAKİ İLİŞKİ. Medical Research Reports, Volume: 8 Issue: 1. https://doi.org/10.55517/mrr.1524149

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