Dergiler / Çocuk Enfeksiyon Dergisi / 2019 / Cilt: 13 - Sayı: 4

Determination of Epidemiology and Seasonal Distribution of Viral Agents Detected in Children with Respiratory Tract Infection

Solunum Yolu Enfeksiyonlu Çocuklarda Saptanan Viral Etkenlerin Epidemiyolojisi ve Mevsim Dağılımının Belirlenmesi

Sayfa
158–164
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

For this reason, the rapid and sensitive diagnosis of viruses causing viral respirato-ry infections will reduce the cost of treatment, reduce unnecessary use of antibiotics and prevent the development of resistance to antibiotics and will guide the clinician to prevent the infections caused by these viruses

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objective: The aim of this study was to determine the viral pathogens in the respiratory tract infections of children who applied to various outpatient clinics of our hospital and to investigate their seasonal distribution.
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Temel Bulgular & Veri:Material and Methods: Between January 2016 and January 2017, 997 children (45.1% female, 54.9% male, 0 month-17 years) who were diagnosed with upper or lower respiratory tract infection were included in the study.
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Sonuç & Katkı:For this reason, the rapid and sensitive diagnosis of viruses causing viral respirato-ry infections will reduce the cost of treatment, reduce unnecessary use of antibiotics and prevent the development of resistance to antibiotics and will guide the clinician to prevent the infections caused by these viruses
🔬Tür:Araştırma Makalesi
📍Kapsam:2016 Verileri
⚙️Değişkenler:Alan Parametreleri

Özet

Objective: The aim of this study was to determine the viral pathogens in the respiratory tract infections of children who applied to various outpatient clinics of our hospital and to investigate their seasonal distribution. Material and Methods: Between January 2016 and January 2017, 997 children (45.1% female, 54.9% male, 0 month-17 years) who were diagnosed with upper or lower respiratory tract infection were included in the study. Twenty-one viral respiratory pathogens were analyzed by multiplex polymerase chain reaction method by using Fast Track FTD kit (Fast Track Diagnosis, Luxemburg). Results: One or more respiratory viruses were detected in 761 (76.3%) of 997 patients and no virus was detected in 236 (22.8%) of the patients. In our study, distrubition of respiratory tract viruses were as; Adenovirus (2.76%), Bocavirus (4.20%), Coronavirus 229E (0.92%), Coronavirus OC43 (6.96%), Enterovirus (6.04%), Metapneumovirus A (4.60%), Metapneumovirus B (4.47%), Parainfluenza 1 (0.13%), Parainfluenza 2 (1.18%), Parainfluenza 3 (8.80%), Parainfluenza 4 (1.18%), Parainfluenza 4a (0.13%), Parainfluenza 4b (0.13%), Rhinovirus (48.75%), RSVA/B (37.84%), Influenza B (3.02%) and Parechovirus (6.57%). When we observe the seasonal distribution of viral agents, RSV was the most common agent in winter and it was rhinovirus in spring, summer and autumn season. Conclusion: Approximately 80% of the patients included in the study had a viral agent that may be responsible for clinical symptoms. For this reason, the rapid and sensitive diagnosis of viruses causing viral respirato-ry infections will reduce the cost of treatment, reduce unnecessary use of antibiotics and prevent the development of resistance to antibiotics and will guide the clinician to prevent the infections caused by these viruses

Abstract

Giriş: Bu çalışmada hastanemizin çeşitli klinik ve polikliniklerine başvuran çocuk hastaların solunum yolu enfeksiyonlarında viral patojenlerin saptanması ve mevsimsel dağılımının araştırılması amaçlanmıştır. Gereç ve Yöntemler: Bu çalışmaya, Ocak 2016-Ocak 2017 tarihleri arasında, üst veya alt solunum yolu enfeksiyonu ön tanısı alan, belirtileri ile hastaneye başvuran 997 çocuk (%45.1 kadın, %54.9 erkek, yaş aralığı 0 ay-17 yaş) dahil edildi. Hastalardan alınan örneklerden 21 viral solunum patojeni, Fast Track FTD Respiratory pathogens 21 (Fast Track Diagnosis, Luxemburg) kiti kullanılarak multipleks polimeraz zincir reaksiyonu yöntemi ile araştırıldı. Bulgular: Toplam 997 hastanın, 761 (%76.3)’inde bir veya birden fazla solunum virüsü saptanmış olup hastaların 236 (%22.8)’sında virüs saptanmamıştır. Çalışmamızda solunum yolu virüslerinin dağılımı; Adenovirüs (%2.76), Bokavirüs (%4.20), Koronavirüs 229E (%0.92), Koronavirüs OC43 (%6.96), Enterovirüs (%6.04), Metapnömovirüs A (%4.60), Metapnömovirüs B (%4.47), Parainfluenza 1 (%0.13), Parainfluenza 2 (%1.18), Parainfluenza 3 (%8.80), Parainfluenza 4 (%1.12), Parainfluenza 4a (%0.13), Parainfluenza 4b (%0.13), Rinovirüs (%48.75), RSV A/B (%37.84), İnfluenza B (%3.02), Parekovirüs (%6.57) şeklindedir. Etkenlerin mevsimsel dağılımına baktığımızda kış mevsiminde en sık rastlanılan etken RSV, ilkbahar, yaz ve sonbahar mevsiminde ise rinovirüs olmuştur. Sonuç: Çalışmaya dahil edilen hastaların yaklaşık %80’inde klinik belirtilerden sorumlu olabilecek bir viral etken saptanmıştır. Bu nedenle viral solunum yolu enfeksiyonlarına neden olan virüslerin hızlı ve duyarlı tanısı tedavi maliyetini düşürecek, gereksiz antibiyotik kullanımını azaltacak ve antibiyotiklere direnç gelişimini engelleyecek ayrıca bu virüslerin neden olabilecekleri hastane enfeksiyonlarının önlenebilmesi açısından klinisyene yol gösterici olacaktır.

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Bu Makaleye Atıf Yap

TOKAK, S., GÜLSEREN, Y. D., ÖZDEMİR, M. (2019). Determination of Epidemiology and Seasonal Distribution of Viral Agents Detected in Children with Respiratory Tract Infection. Çocuk Enfeksiyon Dergisi, Cilt: 13 - Sayı: 4, 158–164. https://ajindex.com/articles/151798

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