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Dergiler / Journal of Health Sciences and Medicine / 2026 / Volume: 9 Issue: 2

Koroner arter hastalığının değerlendirilmesinde epicardiyal yağ doku hacmi ve perikoronary yağ kalınlığının rolü

The role of epicardial adipose tissue volume and pericoronary fat thickness in the evaluation of coronary artery disease

Enes Gül(Sivas Cumhuriyet Üniversitesi Tıp Fakültesi)0000-0002-5562-2697
Onur Çetin(SİVAS CUMHURİYET ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ)0009-0001-0014-9812
İrfan Atik(SİVAS CUMHURİYET ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ)0000-0002-9026-2076
Mehmet Haydar Atalar(SİVAS CUMHURİYET ÜNİVERSİTESİ, TIP FAKÜLTESİ, DAHİLİ TIP BİLİMLERİ BÖLÜMÜ)0000-0003-3076-8072
Sayfa
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Yayın Tarihi
2026-03-12
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Bulgular: Yapılan analizlerde, aterosklerotik grubun EFV ve PCFT değerlerinin anlamlı şekilde yüksek olduğu, ancak EFD'nin bu grupta düşük olduğu gözlemlenmiştir.

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Amaç & Hipotez:Amaçlar: Bu çalışmanın amacı, epikardiyal yağ doku hacmi (EFV), epikardiyal yağ doku dansitesi (EFD) ve perikoroner yağ dokusu kalınlığının (PCFT) koroner kalsiyum skoru (CS) ile ilişkisini incelemektir.
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Temel Bulgular & Veri:Metodlar: Çalışma, Ocak 2025 ile Ekim 2025 arasında kardiyak BT anjiyografi yapılan 255 hasta üzerinde retrospektif olarak gerçekleştirilmiştir.
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Sonuç & Katkı:Bulgular: Yapılan analizlerde, aterosklerotik grubun EFV ve PCFT değerlerinin anlamlı şekilde yüksek olduğu, ancak EFD'nin bu grupta düşük olduğu gözlemlenmiştir.
🔬Tür:Deneysel Tarla Denemesi
📍Kapsam:2025 · 255 hasta
⚙️Değişkenler:Coronary calcium score · coronary artery disease · epicardial fat tissue

Özet

Amaçlar: Bu çalışmanın amacı, epikardiyal yağ doku hacmi (EFV), epikardiyal yağ doku dansitesi (EFD) ve perikoroner yağ dokusu kalınlığının (PCFT) koroner kalsiyum skoru (CS) ile ilişkisini incelemektir. Epikardiyal yağ doku koroner arterlerin etrafını saran bir yağ dokusu olup kardiyovasküler hastalıklarla ilişkili olduğu düşünülmektedir. Metodlar: Çalışma, Ocak 2025 ile Ekim 2025 arasında kardiyak BT anjiyografi yapılan 255 hasta üzerinde retrospektif olarak gerçekleştirilmiştir. Çalışmaya alınanların EFV, EFD ve PCFT ölçümleri yapıldı. Bulgular: Yapılan analizlerde, aterosklerotik grubun EFV ve PCFT değerlerinin anlamlı şekilde yüksek olduğu, ancak EFD'nin bu grupta düşük olduğu gözlemlenmiştir. Ayrıca, EFV'nin koroner kalsiyum varlığıyla anlamlı bir şekilde pozitif korelasyon gösterdiği, buna karşın EFD ile herhangi bir anlamlı korelasyon bulunmadığı tespit edilmiştir. Binary lojistik regresyon analizinde yaş, diyabet, hipertansiyon, EFV ve RCA-PCFT'nin koroner kalsiyum varlığı üzerinde etkili olduğu görüldü. Ayrıca ordinal regresyonda yalnızca hipertansiyon ve yaşın kalsiyum skor derecesine etki ettiği görüldü. Sonuç: Çalışmanın bulguları epikardiyal yağ dokusunun, koroner arter hastalığına dair potansiyel biyomarker olarak kullanılabileceğini düşündürmektedir.

Abstract

Aims: To investigate the relationships between epicardial fat volume (EFV), epicardial fat tissue density (EFD), and pericoronary fat tissue thickness (PCFT) and the coronary calcium score (CS). Epicardial fat tissue, which surrounds the coronary arteries, is thought to be associated with cardiovascular diseases. Methods: The study was conducted retrospectively on 255 patients who underwent cardiac CT angiography between January 2025 and October 2025. EFV, EFD, and PCFT measurements were performed on the study participants. Results: The analysis revealed that EFV and PCFT were significantly higher in the atherosclerotic group, whereas EFD was lower in this group. Additionally, a significant positive correlation was observed between EFV and coronary calcium, whereas no significant correlation was observed with EFD. In the binary logistic regression analysis, age, diabetes, hypertension, EFV, and RCA-PCFT were associated with the presence of coronary calcium. Furthermore, in ordinal regression, only hypertension and age were associated with the calcium score. Conclusion: The findings of this study suggest that epicardial fat may serve as a biomarker for coronary artery disease.

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Bu Makaleye Atıf Yap

Gül, E., Çetin, O., Atik, İ., Atalar, M. H. (2026). Koroner arter hastalığının değerlendirilmesinde epicardiyal yağ doku hacmi ve perikoronary yağ kalınlığının rolü. Journal of Health Sciences and Medicine, Volume: 9 Issue: 2. https://doi.org/10.32322/jhsm.1841331

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