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Dergiler / International Journal of Life Sciences and Biotechnology / 2021 / Cilt: 4 Sayı: 3

Phytochemical screening and in vitro evaluation of the antiarthritic activity of Nigella sativa L. seeds extracts

Mohammed Cheurfa(University of Djillali Bounaama-Khemis Miliana,)0000-0001-9722-1173
Abdalbasit Marıod(Indigenous Knowledge and Heritage Center, Ghibaish College of Science & Technology, Ghibaish, Sudan.)0000-0003-3237-7948
Kaddour Yahya(University of Djillali Bounaama-Khemis Miliana)0000-0002-0044-1450
Benmbarek İslam(University of Djillali Bounaama-Khemis Miliana)0000-0002-5519-2252
Sayfa
381–388
Yayın Tarihi
2021-12-15
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The results of antiarthritic activity showed an important effect of the aqueous and hydroalcoholic extracts on the inhibition of inflammation.The results of this study show that the seed extracts exhibited an important anti-inflammatory effect.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:The objective of this study was the evaluation of the antiarthritic activity as well as the phytochemical screening of Nigella sativa L. seeds extracts in vitro.
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Temel Bulgular & Veri:The dosage of flavonoids have shown that the content found in the hydroalcoholic extract (134.7 ± 0.289 mg QE / g) was significantly higher compared to the aqueous extract (48.495 ± 0.035mg QE / g).
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Sonuç & Katkı:The results of antiarthritic activity showed an important effect of the aqueous and hydroalcoholic extracts on the inhibition of inflammation.The results of this study show that the seed extracts exhibited an important anti-inflammatory effect.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Nigella Sativa L · Aqueous extract · Hydroalcoholic extract

Abstract

The objective of this study was the evaluation of the antiarthritic activity as well as the phytochemical screening of Nigella sativa L. seeds extracts in vitro. The dosage of flavonoids have shown that the content found in the hydroalcoholic extract (134.7 ± 0.289 mg QE / g) was significantly higher compared to the aqueous extract (48.495 ± 0.035mg QE / g). The phytochemicals analysis of the extracts revealed the presence of tannins, saponins and reducing compounds and the absence of alkaloids. The results of antiarthritic activity showed an important effect of the aqueous and hydroalcoholic extracts on the inhibition of inflammation.The results of this study show that the seed extracts exhibited an important anti-inflammatory effect.

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Bu Makaleye Atıf Yap

Cheurfa, M., Marıod, A., Yahya, K., İslam, B. (2021). Phytochemical screening and in vitro evaluation of the antiarthritic activity of Nigella sativa L. seeds extracts. International Journal of Life Sciences and Biotechnology, Cilt: 4 Sayı: 3, 381–388. https://doi.org/10.38001/ijlsb.868282

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