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Dergiler / Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi / 2026 / Issue: 1

Sternbergia sicula, S. lutea ve Pancratium maritimum Ekstrelerinin In vitro Sitotoksik Aktiviteleri

In vitro Cytotoxic Activity of Sternbergia sicula, S. lutea and Pancratium maritimum Extracts

Gülen İrem Kaya(Ege University, Faculty of Pharmacy, Department of Pharmacognosy, 35100 BornovaIzmir TURKEY)
Buket Sarıkaya(Ege University, Faculty of Pharmacy, Department of Pharmacognosy, 35100 BornovaIzmir TURKEY)
Derya Çiçek(Ege University, Faculty of Pharmacy, Department of Pharmacognosy, 35100 BornovaIzmir TURKEY)
Nehir Ünver Somer(Ege University, Faculty of Pharmacy, Department of Pharmacognosy, 35100 BornovaIzmir TURKEY)
Sayfa
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Yayın Tarihi
2010-01-01
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Sonuç olarak bütün bitkilerin soğanlarından hazırlanan etanol ekstreleri belirgin aktivite göstermiştir.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Ker-Gawl ex Sprengel, S sicula Tineo ex Guss. ve Pancratium. maritimum L. bitkilerinin soğanları ve toprak üstü kısımlarına ait n-hekzan, etilasetat, etanol ve su ekstrelerinin sitotoksik aktiviteleri brine shrimp Artemia salina Leach. yöntemi ile tayini edilmiştir.
📊
Temel Bulgular & Veri:Sonuç olarak bütün bitkilerin soğanlarından hazırlanan etanol ekstreleri belirgin aktivite göstermiştir.
💡
Sonuç & Katkı:P. maritimum bitkisinin soğan ve toprak üstü su ekstreleri aktif çıkarken, S. sicula soğanları ve S. lutea toprak üstü kısımlarından hazırlanan su ekstreleri belirgin sitotoksik aktivite göstermiştir.
🔬Tür:Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:S.lutea · S sicula · P. maritimum

Özet

S.lutea L. Ker-Gawl ex Sprengel, S sicula Tineo ex Guss. ve Pancratium. maritimum L. bitkilerinin soğanları ve toprak üstü kısımlarına ait n-hekzan, etilasetat, etanol ve su ekstrelerinin sitotoksik aktiviteleri brine shrimp Artemia salina Leach. yöntemi ile tayini edilmiştir. Sonuç olarak bütün bitkilerin soğanlarından hazırlanan etanol ekstreleri belirgin aktivite göstermiştir. Ancak bitkilerin toprak üstü kısımlarından hazırlanan n-hekzan, etilasetat ve etanol ekstrelerinin hiçbirinde aktivite bulunmamıştır. P. maritimum bitkisinin soğan ve toprak üstü su ekstreleri aktif çıkarken, S. sicula soğanları ve S. lutea toprak üstü kısımlarından hazırlanan su ekstreleri belirgin sitotoksik aktivite göstermiştir.

Abstract

The cytotoxic activity of the n-hexane, ethyl acetate, ethanolic and aqueous extracts of the bulbs and aerial parts of S.lutea L. Ker-Gawl ex Sprengel, S sicula Tineo ex Guss. and P. maritimum L. were determined using the brine shrimp Artemia salina Leach. lethality bioassay. As a result, all of the ethanolic extracts of the bulbs showed significant activity. However, none of the n-hexane, ethyl acetate, ethanolic extracts of the aerial parts were active against Artemia salina Leach. The aqueous extracts of bulbs and aerial parts of P. maritimum were found to be active whereas aqueous extracts prepared from S. sicula bulbs and aerial parts of S. lutea showed significant activity.

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Bu Makaleye Atıf Yap

Kaya, G. İ., Sarıkaya, B., Çiçek, D., Somer, N. Ü. (2010). Sternbergia sicula, S. lutea ve Pancratium maritimum Ekstrelerinin In vitro Sitotoksik Aktiviteleri. Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi, Issue: 1. https://ajindex.com/articles/1489531

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