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Dergiler / Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi / 2026 / Volume: 46 Issue: 1

Terpenes in Mushrooms: Natural Products with Diverse Therapeutic Activities

Eda Avcı(ANKARA MEDİPOL ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİ)0009-0009-4807-810X
Ayşe Kuruüzüm-uz(HACETTEPE UNIVERSITY, FACULTY OF PHARMACY)0000-0003-3373-4759
Didem Şöhretoğlu(HACETTEPE ÜNİVERSİTESİ, ECZACILIK FAKÜLTESİ, ECZACILIK PR.)0000-0002-8264-5544
Sayfa
—
Yayın Tarihi
2026-03-01
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

However, the authors underscore the necessity for further in vitro studies to elucidate the mechanisms of action, along with in vivo studies, toxicity investigations, and clinical trials.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:This study provides a comprehensive review of the terpenes found in mushrooms and their potential therapeutic applications.
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Temel Bulgular & Veri:Mushrooms are rich sources of various terpenes, including monoterpenes, sesquiterpenes, diterpenes, and triterpenes, which possess antibacterial, antiviral, antifungal, antiparasitic, antioxidant, anti-inflammatory, antidiabetic, and cytotoxic activities.
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Sonuç & Katkı:However, the authors underscore the necessity for further in vitro studies to elucidate the mechanisms of action, along with in vivo studies, toxicity investigations, and clinical trials.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Bioactive compounds · Mushrooms · Natural products

Abstract

This study provides a comprehensive review of the terpenes found in mushrooms and their potential therapeutic applications. Mushrooms are rich sources of various terpenes, including monoterpenes, sesquiterpenes, diterpenes, and triterpenes, which possess antibacterial, antiviral, antifungal, antiparasitic, antioxidant, anti-inflammatory, antidiabetic, and cytotoxic activities. Notable examples include pleuromutilin, a precursor of the antibiotic retapamulin; ganoderic acids from Ganoderma lucidum with anti-HIV effects; sesquiterpenes from Albatrellus dispansus that are effective against phytopathogenic fungi; and lanostane triterpenes from G. lucidum and G. leucocontextum with neuroprotective effects. The present findings highlight the therapeutic potential of mushroom terpenes. However, the authors underscore the necessity for further in vitro studies to elucidate the mechanisms of action, along with in vivo studies, toxicity investigations, and clinical trials.

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Bu Makaleye Atıf Yap

Avcı, E., Kuruüzüm-uz, A., Şöhretoğlu, D. (2026). Terpenes in Mushrooms: Natural Products with Diverse Therapeutic Activities. Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi, Volume: 46 Issue: 1. https://doi.org/10.52794/hujpharm.1790368

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