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Dergiler / Experimental and Applied Medical Science / 2023 / Cilt: 4 Sayı: 4

The “Eye of the tiger sign” in Progressive Supranuclear Palsy: Is it a coincidence or not?

Hamit Genç(Gaziantep Dr. Ersin Arslan Training and Research Hospital)0000-0002-6198-2883
Nevra Öksüz(MERSIN UNIVERSITY, SCHOOL OF MEDICINE)0000-0003-4825-7457
Okan Doğu(MERSIN UNIVERSITY, SCHOOL OF MEDICINE)0000-0002-2126-9792
Sayfa
595–600
Yayın Tarihi
2024-02-12
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

In this report, we aimed to contribute to the literature by presenting two PSP cases in which the “eye of the tiger” sign was observed.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Progressive supranuclear palsy (PSP); is a neurodegenerative disorder involved in atypical parkinsonism syndromes.
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Temel Bulgular & Veri:The classical clinical presentation is postural instability, falls, downward paralysis, frontal dementia, and symmetric akinetic-rigid parkinsonism.
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Sonuç & Katkı:In this report, we aimed to contribute to the literature by presenting two PSP cases in which the “eye of the tiger” sign was observed.
🔬Tür:Olgu Sunumu
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Progressive supranuclear palsy · the “eye of the tiger” sign · iron accumulation

Abstract

Progressive supranuclear palsy (PSP); is a neurodegenerative disorder involved in atypical parkinsonism syndromes. The classical clinical presentation is postural instability, falls, downward paralysis, frontal dementia, and symmetric akinetic-rigid parkinsonism. The atrophy of the mesencephalon in magnetic resonance imaging (MRI) is an important marker in diagnosing the disease. Recently, a few PSP cases reported the “eye of the tiger” sign on MRI. The “eye of the tiger” sign, in globus pallidus, is a sign that bilaterally symmetrically located low signal intensity and central longitudinal hyperintensity are observed. While previously a specific finding for the pantothenate kinase-associated neurodegeneration (PKAN), it is no longer considered specific because of the reported cases of non-PKAN with the “eye of the tiger” sign such as neuropherritinopathy, multi-system atrophy, corticobasal degeneration. In this report, we aimed to contribute to the literature by presenting two PSP cases in which the “eye of the tiger” sign was observed.

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Bu Makaleye Atıf Yap

Genç, H., Öksüz, N., Doğu, O. (2024). The “Eye of the tiger sign” in Progressive Supranuclear Palsy: Is it a coincidence or not?. Experimental and Applied Medical Science, Cilt: 4 Sayı: 4, 595–600. https://doi.org/10.46871/eams.1322881

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Kaynakça (13)

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