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Dergiler / Eurasian Journal of Biological and Chemical Sciences / 2026 / Volume: 4 Issue: 1

Phytochemical screening and anthelmintic activity of leafand seed extract of Cassia occidentelis L.

Faiza Shafi(Mirpur University of Science and Technology)
Muhammad Ajaib(Mirpur University of Science and Technology)
Khizar Hayat Bhatti(University of Karachi)
Muhammad Faheem Siddiqui(University of Gujrat)
Afsheen Khan(Federal Urdu University Karachi Pakistan)0000-0001-7557-5210
Sayfa
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Yayın Tarihi
2021-06-29
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So the C. occidentalis plant can be used as anthelmintic drug for the treatment of gastrointestinal helminthic infections after clinical trials, toxicological effects and isolation of chemical compounds.

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Amaç & Hipotez:In present study the ethanolic extracts of leaf and seed of Cassia occidentalis were investigated for their phytochemical properties and anthelmintic activity against Haemonchus controtus at different concentrations (100, 150, 200 mg/ml).
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Temel Bulgular & Veri:Alkaloids, flavonoids, saponins, tannins, phenols, steroids and carbohydrates are present in both leaf and seeds crude extracts.
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Sonuç & Katkı:So the C. occidentalis plant can be used as anthelmintic drug for the treatment of gastrointestinal helminthic infections after clinical trials, toxicological effects and isolation of chemical compounds.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Phytochemicals · Anthelmic activity · Medicinal plants

Abstract

In present study the ethanolic extracts of leaf and seed of Cassia occidentalis were investigated for their phytochemical properties and anthelmintic activity against Haemonchus controtus at different concentrations (100, 150, 200 mg/ml). Alkaloids, flavonoids, saponins, tannins, phenols, steroids and carbohydrates are present in both leaf and seeds crude extracts. The study is mainly concerned with the determination of time of paralysis and time of death of the worms. When there was a gradual increase in the dose, a gradual increase in the anthelmintic activity was observed. The least time for the death and paralysis was recorded at concentration of 50mg/mL and maximum time for death and paralysis was recorded at 10mg/mL concentration. The ethanolic extract of the leaf and seed showed a significant anthelmintic activity at highest concentration of 50 mg/ml. So the C. occidentalis plant can be used as anthelmintic drug for the treatment of gastrointestinal helminthic infections after clinical trials, toxicological effects and isolation of chemical compounds.

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Bu Makaleye Atıf Yap

Shafi, F., Ajaib, M., Bhatti, K. H., Siddiqui, M. F., Khan, A. (2021). Phytochemical screening and anthelmintic activity of leafand seed extract of Cassia occidentelis L.. Eurasian Journal of Biological and Chemical Sciences, Volume: 4 Issue: 1. https://doi.org/10.46239/ejbcs.863842

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Kaynakça (15)

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