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Dergiler / Black Sea Journal of Health Science / 2026 / Cilt: 5 Sayı: 1

Eosinophilic Pleuropericardial Effusion due to Valproic Acid

Fatma Şimşek(ATATÜRK ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-1662-5534
Nazım Kızıldağ(ERZURUM TECHNICAL UNIVERSITY, FACULTY OF HEALTH SCIENCES)0000-0003-1655-5695
Sayfa
104–106
Yayın Tarihi
2022-01-01
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

But it is seen that it is an important factor in drug dosage.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Valproic acid is widely used in the treatment of many diseases.
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Temel Bulgular & Veri:Case report; a 31-year-old male patient who had been using valproic acid since childhood due to epilepsy presented with respiratory distress.
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Sonuç & Katkı:But it is seen that it is an important factor in drug dosage.
🔬Tür:Olgu Sunumu
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Valproic acid · Pleuropericardial effusion · Epilepsy

Abstract

Valproic acid is widely used in the treatment of many diseases. It has common side effects such as nausea, vomiting, diarrhea, dizziness, tremor, hair loss, thrombocytopenia. Valproic acid can rarely cause eosinophilic pleuropericardial effusion. Case report; a 31-year-old male patient who had been using valproic acid since childhood due to epilepsy presented with respiratory distress. Eosinophilic pleuropericardial effusion was detected in the examinations performed in the patient with progressive respiratory distress. After excluding other etiological causes, this condition is assumed to be related to valproic acid. Drug changes were made. The end of six months, was observed to be completely cured. Conclusion: This adverse is generally thought to result from drug hypersensitivity reaction. But it is seen that it is an important factor in drug dosage.

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Bu Makaleye Atıf Yap

Şimşek, F., Kızıldağ, N. (2022). Eosinophilic Pleuropericardial Effusion due to Valproic Acid. Black Sea Journal of Health Science, Cilt: 5 Sayı: 1, 104–106. https://doi.org/10.19127/bshealthscience.930247

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Kaynakça (10)

  1. Adelman M, Albelda SM, Gottlieb J, Haponik EF. 1984. Diagnostic utility of pleural fluid eosinophilia. The American J Med, 77(5): 915-920.
  2. André S, Drowart A, De Bels D. 2005. Lymphocytic pleural effusion associated with valproic acid. European J Inter Med, 16(7): 535.
  3. Antony VB. 1998. Drug-induced pleural disease. Clinics in chest Med, 19(2): 331-340.
  4. Bally C, Martin C, Kraoua S, Kanaan R, Lacronique J, Dusser D, Burgel P. 2011. Eosinophilic pleural effusion related to taking valproic acid. Revue de Pneum Clin, 67(6): 363.
  5. Heidecker J, Kaplan A, Sahn SA. 2006. Pleural fluid and peripheral eosinophilia from hemothorax: Hypothesis of the pathogenesis of EPE in hemothorax and pneumothorax. The American J Med Sci, 332(3): 148-152.
  6. Huggins JT, Sahn SA. 2004. Drug-induced pleural disease. Clinics in Chest Med, 25(1): 141-153.
  7. Kalomenidis I, Light RW. 2003. Eosinophilic pleural effusions. Current Opin Pulmon Med, 9(4): 254-260.
  8. Kaufman J, O'Shaughnessy IM. 1995. Eosinophilic pleural effusion associated with valproic acid administration. Southern Med J, 88(8): 881-882.
  9. Krenke R, Nasilowski J, Korczynski P, Gorska K, Przybylowski T, Chazan R, Light RW. 2009. Incidence and aetiology of eosinophilic pleural effusion. European Respir J, 34(5): 1111-1117.
  10. Rubins JB, Rubins HB. 1996. Etiology and prognostic significance of eosinophilic pleural effusions: a prospective study. Chest, 110(5): 1271-1274.