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Dergiler / Bayburt Üniversitesi Fen Bilimleri Dergisi / 2026 / Cilt: 9 Sayı: 1

Synthesis, Structural Characterization and Antimicrobial Activity of Ni(II) Complex from 4,4’-Ethylenedipyridine and Aniline-2,5-Disulfonic acid

Nurgün Büyükkıdan(KÜTAHYA DUMLUPINAR ÜNİVERSİTESİ)0000-0001-6879-9355
Seda Bozyel Turgut(KÜTAHYA DUMLUPINAR ÜNİVERSİTESİ)0000-0003-1473-6038
Halil İlkimen(KÜTAHYA DUMLUPINAR ÜNİVERSİTESİ)0000-0003-1747-159X
Aysel Gülbandılar(ESKİŞEHİR OSMANGAZİ ÜNİVERSİTESİ)0000-0001-9075-9923
Sayfa
1–9
Yayın Tarihi
2026-06-30
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

As a result, the synthesized compound (2) can be assessed for use in the synthesis of new antibacterial compounds.

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Amaç & Hipotez:In this study, the salt {1, (H2edp)(adsa)}, obtained from 4,4’-ethylenedipyridine (edp) and aniline-2,5-disulfonic acid (H2adsa) and new Ni(II) complex {[Ni2(edp)4(H2O)8](adsa)2.3H2O, 2} were synthesized.
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Temel Bulgular & Veri:In addition, antimicrobial activities of edp, H2adsa, 1, and 2 against Escherichia coli (ATCC 25922), Enterococcus faecalis (ATCC 29212), Pseudomonas aeruginosa (ATCC 27853), Listeria monocytogenes (ATCC 7644), and Staphylococcus aureus (NRRL-B 767), and Bacillus subtilis bacteria and Candida albicans (F89) yeast were investigated using the microdilution method and compared with existing antibiotics (cefepime, vancomycin, levofloxacin, chloramphenicol, fluconazole, and ketoconazole).
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Sonuç & Katkı:As a result, the synthesized compound (2) can be assessed for use in the synthesis of new antibacterial compounds.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:4'-Ethylenedipyridine · Aniline-2 · 5-disulfonic acid

Özet

In this study, the salt {1, (H2edp)(adsa)}, obtained from 4,4’-ethylenedipyridine (edp) and aniline-2,5-disulfonic acid (H2adsa) and new Ni(II) complex {[Ni2(edp)4(H2O)8](adsa)2.3H2O, 2} were synthesized. The complex was defined by using elemental analysis, AAS, IR, UV-Vis, and magnetic susceptibility techniques. In addition, antimicrobial activities of edp, H2adsa, 1, and 2 against Escherichia coli (ATCC 25922), Enterococcus faecalis (ATCC 29212), Pseudomonas aeruginosa (ATCC 27853), Listeria monocytogenes (ATCC 7644), and Staphylococcus aureus (NRRL-B 767), and Bacillus subtilis bacteria and Candida albicans (F89) yeast were investigated using the microdilution method and compared with existing antibiotics (cefepime, vancomycin, levofloxacin, chloramphenicol, fluconazole, and ketoconazole). As a result of the activity studies, edp for E. coli, edp, H2adsa, and 2 for E. faecalis, edp, H2adsa, 1, and 2 for P. aeruginosa, edp and 2 for L. monocytogenes, H2adsa for S. aureus, edp, H2adsa, and 2 for B. subtilis, and H2adsa for C. albicans have the best activity. As a result, the synthesized compound (2) can be assessed for use in the synthesis of new antibacterial compounds.

Abstract

In this study, the salt {1, (H2edp)(adsa)}, obtained from 4,4’-ethylenedipyridine (edp) and aniline-2,5-disulfonic acid (H2adsa) and new Ni(II) complex {[Ni2(edp)4(H2O)8](adsa)2.3H2O, 2} were synthesized. The complex was defined by using elemental analysis, AAS, IR, UV-Vis, and magnetic susceptibility techniques. In addition, antimicrobial activities of edp, H2adsa, 1, and 2 against Escherichia coli (ATCC 25922), Enterococcus faecalis (ATCC 29212), Pseudomonas aeruginosa (ATCC 27853), Listeria monocytogenes (ATCC 7644), and Staphylococcus aureus (NRRL-B 767), and Bacillus subtilis bacteria and Candida albicans (F89) yeast were investigated using the microdilution method and compared with existing antibiotics (cefepime, vancomycin, levofloxacin, chloramphenicol, fluconazole, and ketoconazole). As a result of the activity studies, edp for E. coli, edp, H2adsa, and 2 for E. faecalis, edp, H2adsa, 1, and 2 for P. aeruginosa, edp and 2 for L. monocytogenes, H2adsa for S. aureus, edp, H2adsa, and 2 for B. subtilis, and H2adsa for C. albicans have the best activity. As a result, the synthesized compound (2) can be assessed for use in the synthesis of new antibacterial compounds.

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Bu Makaleye Atıf Yap

Büyükkıdan, N., Turgut, S. B., İlkimen, H., Gülbandılar, A. (2026). Synthesis, Structural Characterization and Antimicrobial Activity of Ni(II) Complex from 4,4’-Ethylenedipyridine and Aniline-2,5-Disulfonic acid. Bayburt Üniversitesi Fen Bilimleri Dergisi, Cilt: 9 Sayı: 1, 1–9. https://doi.org/10.55117/bufbd.1790705

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