Yapay Zeka Hızlı Bakış & Çıkarımlar
AI InsightDiscussion: Thanks to the premedication of this case and the addition of somatostatin analogue, pheniramine maleate and methylprednisolone to the pump reservoir and avoiding agents such as atracurium, morphine and meperidine, which may cause histamine release, the surgery was accomplished have been accomplished without development of carcinoid crisis.
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Özet
Objective: We present our strategy for successful management of pediatric patients with carcinoid heart disease when weaning from cardiopulmonary bypass (CPB) during tricuspid valve surgery. Case Presentation: The patient was a 14-year-old boy who had been diagnosed with a grade IV neuroendocrine tumor. The patient was premedicated with oral midazolam, hydroxyzine, somatostatin analogue (Octreotide®), and pheniramine maleate. Octreotide® and serotonin 5-hydroxytryptamine receptor antagonist were also added during the rewarming period. Dopamine was continued as an infusion (5 µg kg-1 min-1) for the first day. Bioprosthetic valve placement and transannular right ventricular outflow tract patch augmentation were performed. He was extubated within 20 hours and discharged from the hospital at postoperative 6 day. Discussion: Thanks to the premedication of this case and the addition of somatostatin analogue, pheniramine maleate and methylprednisolone to the pump reservoir and avoiding agents such as atracurium, morphine and meperidine, which may cause histamine release, the surgery was accomplished have been accomplished without development of carcinoid crisis.
Abstract
Amaç: Bu olgu sunumunda karsinoid kalp tutulumu nedeniyle triküspid kapak replasmanı yapılan çocuk hastada kardiyopulmoner baypastan (KPB) ayrılma sırasında uygulanan strateji anlatılmaktadır. Olgu Sunumu: On dört yaşında olan hastamızın evre IV karaciğer metastazı olan nöroendokrin tümörü vardı. Hastaya premedikasyon amacıyla peroral verilen midazolam ve hidroksizinin yanına somatostatin analogu (Octreotid®) ve feniramin maleat ilave edildi. Octreotid® ve 5-hidroksitriptamin reseptör antagonisti aynı zamanda pompa rezervuarına da yapıldı ve ısınma döneminde doz yinelendi. Triküspid kapak yerine biyolojik kapak yerleştirildi ve pulmoner çıkıma krosanüler yama koyuldu. Postoperatif ilk gün 5 µkg-1 dk-1 dopamin infüzyonu devam etti. Cerrahi sonrası 20. saatte ekstübe edilen hasta, postoperatif 6. gün taburcu oldu. Tartışma: Bu olgunun premedikasyonuna ve pompa rezervuarına somatostatin analogu, feniramin maleat ve metilprednizolon ilave edilmesi ve histamin salımınına neden olabilecek atrakuryum, morfin ve meperidin gibi ajanlardan kaçınılması ile karsinoid kriz gelişmeden cerrahinin tamamlanması sağlanmıştır.