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Dergiler / Avrasya Sağlık Bilimleri Dergisi / 2026 / Sayı: 4

Obez Adolesanlarda İki Farklı Diyetin Vücut Ağırlığı ve Metabolik Sağlık Üzerindeki Uzun Vadede Etkileri: Bir Müdahale Çalışması

Long-Term Effects of Two Different Diet on Body Weight and Metabolic Health in Obese Adolescents: An Intervention Study

Rukiye Bozbulut(GAZI UNIVERSITY)0000-0003-4317-9226
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Yayın Tarihi
2026-03-27
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Bulgular: Vücut ağırlığı, BMI, boyun, bel, kalça ve üst orta kol çevresi, yağ yüzdesi ve yağ kütlesi her iki diyet grubunda da anlamlı derecede azalmıştır.

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Amaç & Hipotez:Amaç: Çocukluk çağı obezitesini ve sağlık risklerini azaltmak için alternatif stratejilere ihtiyaç vardır.
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Temel Bulgular & Veri:Bu çalışmanın amacı, Akdeniz diyeti ve düşük yağlı diyetin, obez ergenlerde bir yıl sonra vücut ağırlığı kaybı ve bazı biyokimyasal belirteçler üzerindeki etkilerini araştırmaktır.
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Sonuç & Katkı:Bulgular: Vücut ağırlığı, BMI, boyun, bel, kalça ve üst orta kol çevresi, yağ yüzdesi ve yağ kütlesi her iki diyet grubunda da anlamlı derecede azalmıştır.
🔬Tür:Uygulamalı Anket & Alan Araştırması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:akdeniz diyeti · düşük yağlı diyet · obezite

Özet

Amaç: Çocukluk çağı obezitesini ve sağlık risklerini azaltmak için alternatif stratejilere ihtiyaç vardır. Bu çalışmanın amacı, Akdeniz diyeti ve düşük yağlı diyetin, obez ergenlerde bir yıl sonra vücut ağırlığı kaybı ve bazı biyokimyasal belirteçler üzerindeki etkilerini araştırmaktır. Yöntem: Çalışma, 13-18 yaş arası 40 obez hasta üzerinde yapılmıştır. Katılımcılar, bir yıl boyunca enerji kısıtlaması olmaksızın Akdeniz diyeti ve düşük yağlı diyet olmak üzere iki farklı diyet programına rastgele atanmıştır. Antropometrik değerlendirmeler ve biyokimyasal ölçümler (açlık kan şekeri, insülin, ürik asit, AST, ALT, toplam kolesterol, HDL kolesterol, LDL kolesterol, trigliseritler) başlangıçta ve birinci yılın sonunda yapılmıştır. Bulgular: Vücut ağırlığı, BMI, boyun, bel, kalça ve üst orta kol çevresi, yağ yüzdesi ve yağ kütlesi her iki diyet grubunda da anlamlı derecede azalmıştır. Bununla birlikte, bel-kalça oranı sadece Akdeniz diyeti grubunda azalmıştır (p<0,05). Her iki grupta da insülin, HOMA-IR ve toplam kolesterol düzeyleri azalmıştır (p<0,05). Akdeniz diyeti grubunda HbA1c, trigliserit ve ürik asit düzeyleri anlamlı derecede azalırken, OUICKI düzeyleri anlamlı derecede artmıştır (p<0,05). Sonuç: Hem Akdeniz diyeti hem de düşük yağlı diyet, enerji kısıtlaması olmaksızın uzun dönemde vücut ağırlığı, insülin direnci ve lipid profili üzerinde faydalı etkiler gösterse de, insülin direnci açısından Akdeniz diyetinin düşük yağlı diyete göre daha üstün olduğu bulunmuştur.

Abstract

Objective: There is a need for alternative strategies to reduce childhood obesity and its health risks. The aim of this study was to investigate the effects of the Mediterranean diet and a low-fat diet on weight loss and some biochemical markers in obese adolescents after one year. Method: The study was conducted on 40 obese patients aged 13-18 years. Participants were randomly assigned to two different dietary programs, the Mediterranean diet and the low-fat diet, without energy restriction for one year. Anthropometric assessments and biochemical measurements (fasting blood glucose, insulin, uric acid, AST, ALT, total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides) were performed at baseline and at the end of the first year. Findings: Body weight, BMI, neck, waist, hip and upper mid-arm circumference, fat percentage and fat mass decreased significantly in both diet groups. However, the waist-hip ratio decreased only in the Mediterranean diet group (p<0.05). Insulin, HOMA-IR, and total cholesterol levels decreased in both groups (p<0.05). In the Mediterranean diet group, HbA1c, triglyceride, and uric acid levels decreased significantly, while OUICKI levels increased significantly (p<0.05). Conclusion: Although both the Mediterranean diet and the low-fat diet showed beneficial effects on body weight, insulin resistance, and lipid profile in the long term without energy restriction, the Mediterranean diet was found to be superior to the low-fat diet in terms of insulin resistance

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Bu Makaleye Atıf Yap

Bozbulut, R. (2026). Obez Adolesanlarda İki Farklı Diyetin Vücut Ağırlığı ve Metabolik Sağlık Üzerindeki Uzun Vadede Etkileri: Bir Müdahale Çalışması. Avrasya Sağlık Bilimleri Dergisi, Sayı: 4. https://doi.org/10.53493/avrasyasbd.1870246

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Kaynakça (30)

  1. Al Kindi MK, Al Essry FS, Al Essry FS, Mula-Abed WAS. Validity of serum testosterone, free androgen index, and calculated free testosterone in women with suspected hyperandrogenism. Oman Med J. 2012;27(6):471–4
  2. Álvarez-Pérez J, Sánchez-Villegas A, Díaz-Benítez EM. (2016). Influence of a Mediterranean dietary pattern on body fat distribution: results of the PREDIMED–Canarias intervention randomized trial. J Am Coll Nutr. 2016; 35(6): 568-580.
  3. Baysal A, Aksoy M, Besler H, et al. Diyet el kitabı. Ankara: Hatipoğlu Baskı, 2002.
  4. Chandalia M, Garg A, Lutjohann D, Von Bergmann K, Grundy SM, Brinkley LJ. (2000). Beneficial effects of high dietary fiber intake in patients with type 2 diabetes mellitus. New England Journal of Medicine, 342(19). 1392-1398.
  5. de Graaf, C. (2012). Texture and satiation: the role of oro-sensory exposure time. Physiology & behavior, 107(4), 496- 501.
  6. Demol S, Yackobovitch-Gavan M, Shalitin S, Nagelberg N, Gillon-Keren M, Phillip M. (2009). Low-carbohydrate (low & high-fat) versus high-carbohydrate low-fat diets in the treatment of obesity in adolescents. Acta Paediatrica, 98(2):346-51.
  7. Gallardo-Escribano C, Vargas-Candela A, Vilches-Perez A, Muñoz-Melero M, Ruiz-Moreno MI, Benitez-Porres J. (2021). Lifestyle modification improves insulin resistance and carotid Intima-Media thickness in a metabolically healthy obese prepubescent population. Journal of Pediatric Gastroenterology and Nutrition.72(1):127-34.
  8. García-Montero C, Fraile-Martinez O, Gomez-Lahoz AM, Pekarek L, Castellanos AJ, Noguerales-Fraguas F, Ortega MA. (2021). Nutritional components in Western diet versus Mediterranean diet at the gut microbiota–immune system interplay. Implications for health and disease. Nutrients, 13(2), 699.
  9. Kansra AR, Lakkunarajah S, Jay MS. (2021). Childhood and adolescent obesity: a review. Frontiers in pediatrics, 8:581461.
  10. Katz A, Nambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab. 2000;85(7):2402–10.
  11. Kontogianni MD, Chrysohoou C, Panagiotakos DB, Tsetsekou E, Zeimbekis A, Pitsavos C, Stefanadis C. (2012). Adherence to the Mediterranean diet and serum uric acid: the ATTICA study. Scandinavian journal of rheumatology, 41(6): 442- 449.
  12. Kontush A. (2020). HDL and reverse remnant-cholesterol transport (RRT): relevance to cardiovascular disease. Trends Mol Med. 26(12):1086–1100.
  13. Kraschnewski J, Boan J, Esposito J, Sherwood N, Lehman EB, Kephart DK, et al. (2010). Long-term weight loss maintenance in the United States. International journal of obesity, 34(11):1644-54.
  14. Lewandowska A, Rudzki G, Lewandowski T, Bartosiewicz A, Próchnicki M, Stryjkowska-Góra A, Pavlov S. (2025). Overweight and obesity among adolescents: health-conscious behaviours, acceptance, and the health behaviours of their parents. BMC Public Health, 25(1): 418.
  15. López-Gil JF, García-Hermoso A, Martínez-González MÁ, Rodríguez-Artalejo F. (2024). Mediterranean diet and cardiometabolic biomarkers in children and adolescents: A systematic review and meta-analysis. JAMA network open, 7(7): 2421976-2421976.
  16. López-Gil JF, Garcia-Hermoso A, Sotos-Prieto M, Cavero- Redondo I, Martinez-Vizcaino V, Kales SN. (2023). Mediterranean diet-based interventions to improve anthropometric and obesity indicators in children and adolescents: a systematic review with meta-analysis of randomized controlled trials. Advances in Nutrition, 14(4): 858-869.
  17. Mirza NM, Palmer MG, Sinclair KB, McCarter R, He J, Ebbeling CB (2013). Effects of a low glycemic load or a low-fat dietary intervention on body weight in obese Hispanic American children and adolescents: a randomized controlled trial. The American journal of clinical nutrition. 2013;97(2):276- 85.
  18. Radd-Vagenas S, Kouris-Blazos A, Singh MF, Flood VM. (2017). Evolution of Mediterranean diets and cuisine: concepts and definitions. Asia Pacific journal of clinical nutrition, 26(5): 749-763.
  19. Rosi A, Teixo R, Batista N, Calderón-Pérez L, Caimari A, Scazzina F. (2024). Multicenter Randomized Controlled Trial to Tackle Obesity through a Mediterranean Diet vs. A Low- Fat Diet in Children and Adolescents: Preliminary Results from the MED4YOUTH STUDY. In Proceedings 91(1):126
  20. Sarsangi P, Salehi-Abargouei A, Ebrahimpour-Koujan S, Esmaillzadeh A. (2022). Association between adherence to the Mediterranean diet and risk of type 2 diabetes: an updated systematic review and dose–response meta-analysis of prospective cohort studies. Advances in Nutrition, 13(5): 1787-1798.
  21. Schwartz C, King N, Perreira B, Blundell J, Thivel D (2017). A systematic review and meta-analysis of energy and macronutrient intake responses to physical activity interventions in children and adolescents with obesity. Pediatric obesity. 12(3):179-94.
  22. Serra-Majem L, Ribas L, Ngo J (2004). Food, youth and the Mediterranean diet in Spain. Development of KIDMED, Mediterranean diet quality index in children and adolescents. Public Health Nutr. 7(7): 931-935
  23. Sondike SB, Copperman N, Jacobson MS. (2003). Effects of a low-carbohydrate diet on weight loss and cardiovascular risk factor in overweight adolescents. The Journal of pediatrics, 142(3): 253-258.
  24. Suza DE, Miristia V, Hariati H. (2020). Physical activities and incidence of obesity among adolescent in Medan, Indonesia. Open Access Macedonian Journal of Medical Sciences, 8(E): 198-203.
  25. Vetrani C, Verde L, Colao A, Barrea L, Muscogiuri G. (2023). The Mediterranean diet: Effects on insulin resistance and secretion in individuals with overweight or obesity. Nutrients, 15(21): 4524.
  26. Weigle DS, Cummings DE, Newby PD, Breen PA, Frayo RS, Matthys CC, Purnell JQ. (2003). Roles of leptin and ghrelin in the loss of body weight caused by a low fat, high carbohydrate diet. The Journal of Clinical Endocrinology & Metabolism, 88(4): 1577-1586.
  27. World Health Organization, Obesity and overweight, Geneva, Switzerland. [Internet], 8, December, 2025. Available from: https://www.who.int/news-room/fact-sheets/detail/ obesity-and-overweight:
  28. Yurtdaş G, Akbulut G, Baran M, Yılmaz C. (2022). The effects of Mediterranean diet on hepatic steatosis, oxidative stress, and inflammation in adolescents with non-alcoholic fatty liver disease: A randomized controlled trial. Pediatric Obesity, 17(4): 12872.
  29. Zhang Y, He T, Hu Y, Gao C. (2024). Low-carbohydrate diet is more helpful for weight loss than low-fat diet in adolescents with overweight and obesity: a systematic review and meta-analysis. Diabetes, Metabolic Syndrome and Obesity, 2997-3007.
  30. World Health Organization, Obesity and overweight, Geneva, Switzerland. [Internet], 8, December, 2025. Available from: https://www.who.int/news-room/fact-sheets/detail/ obesity-and-overweight: