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Dergiler / Clinical Dentistry and Research / 2019 / Cilt: 43 - Sayı: 1

EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS

ANKAFERD BLOOD STOPPER İLE GÜÇLENDİRİLMİŞ PLATELETTEN ZENGİN FİBRİN MEMBRANIN DENEYSEL KEMİK DEFEKTLERİNDE YÖNLENDİRİLMİŞ DOKU REJENERASYONU ÜZERİNE ETKİLERİ

TAHA ÖZER
ALPER AKTAŞ
SİYAMİ KARAHAN
Sayfa
3–10
DOI
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Conclusion: The use of Ankaferd Blood Stopper in conjunction with platelet-rich fibrin improves bone healing, strengthens the membrane property of platelet-rich fibrin and promotes better ossification.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Background and Aim: To evaluate the effects of Ankaferd Blood Stopper added platelet-rich fibrin administered in cranial bone defects created in rabbits via histomorphometric assessment.
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Temel Bulgular & Veri:Materials and Method: Four circular 5 mm defects were created in the crania of 16 New Zealand rabbits.
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Sonuç & Katkı:Conclusion: The use of Ankaferd Blood Stopper in conjunction with platelet-rich fibrin improves bone healing, strengthens the membrane property of platelet-rich fibrin and promotes better ossification.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Background and Aim: To evaluate the effects of Ankaferd Blood Stopper added platelet-rich fibrin administered in cranial bone defects created in rabbits via histomorphometric assessment. Materials and Method: Four circular 5 mm defects were created in the crania of 16 New Zealand rabbits. Each defect in each animal received one of four treatments: no treatment (EC group), platelet-rich fibrin administration (PRF group), Ankaferd Blood Stopper added platelet-rich fibrin administration (PRF + ABS group) and collagen membrane administration (CM group). Histomorphometric assessment was conducted at 4 and 8 weeks after surgery. Results: Between-group comparisons of the new bone area revealed significant differences between the PRF + ABS group and the remaining three groups at 4 weeks. The new bone area was significantly larger at 8 weeks than at 4 weeks in all groups. Conclusion: The use of Ankaferd Blood Stopper in conjunction with platelet-rich fibrin improves bone healing, strengthens the membrane property of platelet-rich fibrin and promotes better ossification.

Abstract

Amaç: Ankaferd Blood Stopper ile güçlendirilmiş trombositten zengin fibrinin tavşanlar üzerinde oluşturulan kalvaryal kemik defektleri üzerindeki etkilerinin histomorfometrik yöntemler ile değerlendirmek. Gereç ve Yöntem: 16 Yeni Zelanda tavşanı kafatasında, dörder adet 5 mm çapında dairesel kemik defekti oluşturuldu. Her bir hayvandaki dört farklı defekt bölgesine, dört farklı tedaviden biri uygulandı: tedavi yok (EC grubu), trombositten zengin fibrin uygulaması (PRF grubu), Ankaferd Blood Stopper ile beraber trombositten zengin fibrin uygulaması (PRF + ABS grubu) ve kolajen membran uygulaması (CM grubu). Histomorfometrik değerlendirme cerrahiden 4 ve 8 hafta sonra yapıldı. Bulgular: Yeni kemik alanının gruplar arası karşılaştırmalarında, 4.hafta örneklerinde PRF + ABS grubu ile kalan üç grup arasında anlamlı fark olduğu görüldü. Yeni kemik alanının, tüm gruplarda 8.hafta örneklerinde, 4.hafta örneklerine göre anlamlı derecede yüksek olduğu görüldü. Sonuç: Ankaferd Blood Stopper’ın trombositten zengin fibrin ile birlikte kullanılması; kemik iyileşmesini arttırmakta, trombositten zengin fibrinin membran özelliğini güçlendirmekte ve daha iyi bir kemikleşme sağlamaktadır.

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Bu Makaleye Atıf Yap

ÖZER, T., AKTAŞ, A., KARAHAN, S. (2019). EFFECTS OF ANKAFERD BLOOD STOPPER-REINFORCED PLATELET-RICH FIBRIN MEMBRANE ON GUIDED TISSUE REGENERATION IN EXPERIMENTAL BONE DEFECTS. Clinical Dentistry and Research, Cilt: 43 - Sayı: 1, 3–10. https://ajindex.com/articles/143299

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Kaynakça (10)

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