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Dergiler / Astım Allerji İmmünoloji / 2019 / Cilt: 17 - Sayı: 1

Successful Immunoglobulin Replacement with Subcutaneous Immunoglobulin Therapy in a Patient with Primary Intestinal Lymphangiectasia

Gökhan AYTEKİN
Fatih COLKESEN
Ömür ARDENİZ
Zafer ÇALIŞKANER
Sayfa
57–60
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

We concluded that SCIG should be the preferred route of immunoglobulin replacement therapy in secondary hypogammaglobulinemia due to protein losing enteropathy, especially in PIL.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Primary intestinal lymphangiectasia is a rare disorder which characterized by impaired small intestinal lymph drainage.
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Temel Bulgular & Veri:Herein, we present a 61-year-old patient with immunodeficiency secondary to Primary intestinal lymphangiectasia (PIL), in whom we could attain effective and stable IgG levels only by subcutaneous IgG replacement rather than intravenous IgG.
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Sonuç & Katkı:We concluded that SCIG should be the preferred route of immunoglobulin replacement therapy in secondary hypogammaglobulinemia due to protein losing enteropathy, especially in PIL.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Primary intestinal lymphangiectasia is a rare disorder which characterized by impaired small intestinal lymph drainage. There is loss of proteins from dilated lymphatic channels located in the mucosa, submucosa or subserosa which is results with loss of gammaglobulins and lymphocytes, leading to impaired humoral and cellular immunity. Herein, we present a 61-year-old patient with immunodeficiency secondary to Primary intestinal lymphangiectasia (PIL), in whom we could attain effective and stable IgG levels only by subcutaneous IgG replacement rather than intravenous IgG. Our experience suggests that Subcutaneous Immunoglobulin (SCIG) replacement resulted in more stable levels of IgG in the presented patient with PIL. We concluded that SCIG should be the preferred route of immunoglobulin replacement therapy in secondary hypogammaglobulinemia due to protein losing enteropathy, especially in PIL.

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Bu Makaleye Atıf Yap

AYTEKİN, G., COLKESEN, F., ARDENİZ, Ö., ÇALIŞKANER, Z. (2019). Successful Immunoglobulin Replacement with Subcutaneous Immunoglobulin Therapy in a Patient with Primary Intestinal Lymphangiectasia. Astım Allerji İmmünoloji, Cilt: 17 - Sayı: 1, 57–60. https://ajindex.com/articles/142834

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Kaynakça (12)

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