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Dergiler / Journal of Clinical and Experimental Investigations / 2026 / Cilt: 4 Sayı: 2

Antikoagülasyonun indüklediği hemoperikardiyumlu tamponad: Olgu sunumu ve literatür incelemesi

Anticoagulant-induced hemopericardium with tamponade: A case report and review of the literature

Faruk Ertaş
Nihat Polat
Abdulkadir Yıldız
Mustafa Oylumlu
Mehmet Sıddık Ülgen
Sayfa
229–233
Yayın Tarihi
2013-06-01
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Sonuç olarak warfarin overdoz acil bir durum olup hemoperikardiyumla tamponada yol açabilmektedir.

📌 3 Maddede Bu Makale

🎯
Amaç & Hipotez:Akut kardiyak tamponad acil tanı ve tedavi gerektirir.
📊
Temel Bulgular & Veri:Biz 43 yaşında, erkek ve mitral valv replasmanı sonrası sekiz aydır warfarin tedavisi alan bir olguyu aldık.
💡
Sonuç & Katkı:Sonuç olarak warfarin overdoz acil bir durum olup hemoperikardiyumla tamponada yol açabilmektedir.
🔬Tür:Deneysel Tarla Denemesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Warfarin · hemoperikardiyum · tampo&shy

Özet

Akut kardiyak tamponad acil tanı ve tedavi gerektirir. Biz 43 yaşında, erkek ve mitral valv replasmanı sonrası sekiz aydır warfarin tedavisi alan bir olguyu aldık. Hastanın bir­kaç gündir başlayan nefes darlığı ve halsizlik şikayetikleri mevcuttu. Kardiyak tamponad tanısı konuldu ve 1400 ml mai perikardiyosentezle acil olarak drene edildi. Tanı sı­rasında İNR değeri çok yüksek olan hastaya Vitamin K antagonistleri ve taze donmuş plazma verilerek yuksek koagülasyon durumu geriye döndürüldü. Patolojik incele­me sonucunda enfeksiyon ve malingnensi saptanmadı. Hastada kronik inflamasyon düşünüldü. Sonuç olarak warfarin overdoz acil bir durum olup hemoperikardiyumla tamponada yol açabilmektedir. Bunun için warfarin teda­visi başlanılan hastalarda warfarin dozu ve hedef İNR de­ğerleri sıkı kontrol edilmelidir.

Abstract

Acute cardiac tamponade requires urgent diagnosis and treatment. We report a case of a 43-year-old man who was receiving warfarin treatment for 8 months following mitral valve replacement. The patient had complaint of dyspnea and fatigue for a few days. Cardiac tamponade was diagnosed, and the INR at that time was 10.4. Urgent pericardiocentesis were undertaken and 1400 ml of peri­cardial blood was drained. Following surgery the patient\'s recovery was uneventful. An intravenous vitamin K injec­tion and fresh frozen plasma transfusion were adminis­tered to reverse the patient\'s over-anticoagulated state. The final pathology revealed chronic inflammation and there was no malignancy, and no bacteria or mycobacte­rium were seen. Emergency physicians should remember that over-anticoagulation with warfarin may contribute to certain complications, including hemopericardium, and that strict control of target INR should be the goal for pa­tients who require continuous warfarin treatment. J Clin Exp Invest 2013; 4 (2): 229-233

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Bu Makaleye Atıf Yap

Ertaş, F., Polat, N., Yıldız, A., Oylumlu, M., Ülgen, M. S. (2013). Antikoagülasyonun indüklediği hemoperikardiyumlu tamponad: Olgu sunumu ve literatür incelemesi. Journal of Clinical and Experimental Investigations, Cilt: 4 Sayı: 2, 229–233. https://doi.org/10.5799/ahinjs.01.2013.02.0273

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