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Dergiler / Journal of Clinical and Experimental Investigations / 2026 / Cilt: 7 Sayı: 2

Survival in Operated Early and Local Advanced-Stage (IA-IIIA) Non-Small Cell Lung Cancer

Mahsuk Taylan(DİCLE ÜNİVERSİTESİ)
Sayfa
125–133
Yayın Tarihi
2016-06-10
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J Clin Exp Invest 2016; 7 (2): 125-133 Key words: Survival, mortality, performance score, operated, non-small cell lung cancer

📌 3 Maddede Bu Makale

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Amaç & Hipotez:ABSTRACT Objective: The early and local advanced stages (IA-IIIA) of non-small cell lung cancer (NSCLC) warrant the curative treatment approach of surgery.
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Temel Bulgular & Veri:The aim of the study was to examine the factors that affect survival in operated NSCLC patients with these stages.
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Sonuç & Katkı:J Clin Exp Invest 2016; 7 (2): 125-133 Key words: Survival, mortality, performance score, operated, non-small cell lung cancer
🔬Tür:Araştırma Makalesi
📍Kapsam:2016 Verileri
⚙️Değişkenler:Survival · mortality · performance score

Abstract

ABSTRACT Objective: The early and local advanced stages (IA-IIIA) of non-small cell lung cancer (NSCLC) warrant the curative treatment approach of surgery. However, despite the surgical approach, survival depends on a number of factors. The aim of the study was to examine the factors that affect survival in operated NSCLC patients with these stages. Methods: A cohort of 231 operated patients with IA, IB, IIA, IIB, and IIIA stages of NSCLC were analyzed. The effects of age, sex, comorbidity, performance status, histopathology of the tumor, T stage, N stage, pleural invasion, surgical resection type and postoperative resection margin invasion on the survival of the patients were examined with Kaplan-Meier and Cox Regression analyses. Results: Advanced age (OR=1.042 for every passing year, CI=1.020-1.064), adenocarcinoma histopathology (OR=1.676 CI=1.178-2.384), N2 invasion (OR=2.389 CI=1.46-4.239), pleural invasion (OR=2.403 CI=1.569-3.678), resection margin invasion (OR=2.401, CI=1.141-5.048) and pneumonectomy as the type of surgical operation (OR=2.313, CI=1.467-3.647) were found to be independent prognostic factors of mortality. Conclusion: Follow-up of the NSCLC cases with advanced age, an adenocarcinoma type, visceral pleural invasion, N2-lymph node invasion, a history of pneumonectomy, and a resection margin invasion should be undertaken more atten­tively during planning of surgical operation and postoperative period. J Clin Exp Invest 2016; 7 (2): 125-133 Key words: Survival, mortality, performance score, operated, non-small cell lung cancer

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Bu Makaleye Atıf Yap

Taylan, M. (2016). Survival in Operated Early and Local Advanced-Stage (IA-IIIA) Non-Small Cell Lung Cancer. Journal of Clinical and Experimental Investigations, Cilt: 7 Sayı: 2, 125–133. https://doi.org/10.5799/ahinjs.01.2016.02.0584

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