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Dergiler / Journal of advances in vetbio science and techniques / 2026 / Volume: 9 Issue: 1

Holstein süt ineklerine doğumda koruyucu propilen glikol uygulamasının subklinik ketozise etkisi

Effects of prophylactic propylene glycol administration at calving on subclinical ketosis in Holstein dairy cows

Kemal Aksoy(Muğla Sıtkı Koçman University)0000-0003-0149-6688
Abdülkerim Deniz0000-0002-5242-5671
Sayfa
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Yayın Tarihi
2024-04-30
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Sonuç olarak, PPGT'nin PH2 ve 4'teki kan ve süt BHBA ortalamaları üzerinde önemli bir etkisi olmamasına rağmen, gözlemlenen SKK’nin postpartum hastalıklar ve grup 2'de OGSM kaybı olması SKK riski altındaki ineklerde seçici bir PPGT uygulaması gerektirebilir.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Çalışmaya 19 tedavi grubu (grup 1), 25 kontrol grubu (grup 2) toplam 44 inek katıldı.
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Temel Bulgular & Veri:Grup 1’e doğumla birlikte 3 gün boyunca 300 ml koruyucu propilen glikol tedavisi (PPGT) uygulandı, grup 2 ise herhangi bir uygulama almadı.
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Sonuç & Katkı:Sonuç olarak, PPGT'nin PH2 ve 4'teki kan ve süt BHBA ortalamaları üzerinde önemli bir etkisi olmamasına rağmen, gözlemlenen SKK’nin postpartum hastalıklar ve grup 2'de OGSM kaybı olması SKK riski altındaki ineklerde seçici bir PPGT uygulaması gerektirebilir.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Beta-hydroxybutyric acid · holstein · milk yield

Özet

Çalışmaya 19 tedavi grubu (grup 1), 25 kontrol grubu (grup 2) toplam 44 inek katıldı. Grup 1’e doğumla birlikte 3 gün boyunca 300 ml koruyucu propilen glikol tedavisi (PPGT) uygulandı, grup 2 ise herhangi bir uygulama almadı. Bütün hayvanların postpartum 2. ve 4. haftalarda (PH2 ve PH4) kan ve süt betahidroksibütirik asit konsantrasyonları ölçüldü. Ortalama günlük süt miktarı (OGSM), vücut kondisyon skoru (VKS) ve postpartum hastalıklar (PH) yönünden 90 gün boyunca izlendi. Grup 2’de sırasıyla 2. ve 4. haftada subklinik ketozis (SKK) insidansı kan testinde %8 ve %4 (BHBA≥1,2 mmol/L) ve süt testinde (BHBA≥200 µmol/L) %12 ve %24 (olasılık oranı=5,68) idi. Kan ve süt BHBA'sı grup 1 ve 2 arasında önemli ölçüde farklı değildi. Grup 1'de SKK saptanmadı. Çalışma inekleri doğum sonrası 30 ve 60. günlerde gruplar arasında anlamlı bir fark olmaksızın VKS kaybetti. OGSM, SKK'li KG (28,36 kg), SKK'siz (34,36 kg) ve grup 1 (33,92 kg) arasında önemli ölçüde farklıydı (P<0.05). Mastitis, metritis ve laminitis insidansı hem grup 1 hem de 2'de gözlendi. Ancak klinik ketozis ve sürüden ayırma oranı sadece grup 2'de gözlendi. Mastitis insidansı grup 2 ve 1'de sırasıyla %32 (olasılık oranı: 4.0) ve %10,5 idi. Grup 2'de sürüden ayırma oranı %12 idi, grup 1'de sürüden ayırma gözlenmedi. Sonuç olarak, PPGT'nin PH2 ve 4'teki kan ve süt BHBA ortalamaları üzerinde önemli bir etkisi olmamasına rağmen, gözlemlenen SKK’nin postpartum hastalıklar ve grup 2'de OGSM kaybı olması SKK riski altındaki ineklerde seçici bir PPGT uygulaması gerektirebilir.

Abstract

Forty-four holstein dairy cows were randomly enrolled in the treatment group (group 1, n=19) or control group (group 2, n=25) at calving. Group 1 received prophylactic propylene glycol treatment (PPGT) (300 ml/cow, beginning at calving, total 3 days). The group 2 remained untreated. All animals were tested on blood and milk beta-hydroxybutyric acid (BHBA) at postpartum week 2 and 4 (PW2 and 4), body condition scores (BCS), average daily milk production (ADMP) and postpartum health disorders were monitored in 90 days in milk (90 DIM). The incidence of subclinical ketosis (SCK) was 8% and 4% in blood test (BHBA≥1.2 mmol/L) and by 12% and 24% in milk test (BHBA≥200 µmol/L) in group 2 at PW2 and PW4 respectively. SCK was not detected in group 1. The study cows lost BCS on postpartum days 30 and 60. ADMP was significantly different (P<0.05) between group 2 with SCK, without SCK and group 1. Mastitis, metritis and laminitis incidence were observed both in group 1 and 2, but clinical ketosis and culling rate were observed in group 2 only. Mastitis incidence was 32% and 10.5% in group 2 and group 1 respectively. Culling rate was 12% in group 2, no culling was observed in group 1. Conclusively, although there wasn’t a significant effect of PPGT on the averages of blood and milk BHBA at PW2 and 4, the observed SCK incidence, associated postpartum health disorders and ADMP loss in group 2 can require a selective PPGT in cows at risk for SCK.

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Bu Makaleye Atıf Yap

Aksoy, K., Deniz, A. (2024). Holstein süt ineklerine doğumda koruyucu propilen glikol uygulamasının subklinik ketozise etkisi. Journal of advances in vetbio science and techniques, Volume: 9 Issue: 1. https://doi.org/10.31797/vetbio.1374657

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