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Dergiler / International Journal of Secondary Metabolite / 2026 / Volume: 10 Issue: 3

Biosynthesis of ZnO nanoparticles using Laurus nobilis leaf extract and investigation of antiproliferative and antibacterial activity potential

Firdevs Mert Sivri(Süleyman Demirel University)0000-0002-0545-0268
Ebru Önem(SÜLEYMAN DEMİREL ÜNİVERSİTESİ)0000-0002-7770-7958
Senem Akkoç(SÜLEYMAN DEMİREL ÜNİVERSİTESİ)0000-0002-1260-9425
Cennet Çırrık(SÜLEYMAN DEMİREL ÜNİVERSİTESİ)0009-0002-3361-4570
Aleyna Ezer(SÜLEYMAN DEMİREL ÜNİVERSİTESİ)0009-0005-5629-8576
Sayfa
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Yayın Tarihi
2023-08-27
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The results show that the prepared nanoparticles had antiproliferative in screened incubation time and concentrations.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Nanotechnology has recently emerged as an essential field of study in modern materials science.
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Temel Bulgular & Veri:According to TEM and XRD diffraction analysis, with a mean particle size of 16 ± 5 nm, it was found that the synthesized ZnO NPs contain a hexagonal wurtzite structure.
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Sonuç & Katkı:The results show that the prepared nanoparticles had antiproliferative in screened incubation time and concentrations.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Green synthesis · ZnO NPs · Laurus nobilis leaf

Özet

Nanotechnology has recently emerged as an essential field of study in modern materials science. The green synthesis of nanoparticles using plant extracts is of great interest because it is cost-effective, eco-friendly, and suitable for large-scale production. The study highlights the synthesis of ZnO nanoparticles (ZnO NPs) using Laurus nobilis (L. nobilis) leaf extract and their characterization and biological activities for potential applications in the biomedical field. ZnO NPs were synthesized using Laurus nobilis leaf extract. The synthesized ZnO NPs were characterized by UV-Vis spectroscopy, TEM, XRD, and FT-IR. According to TEM and XRD diffraction analysis, with a mean particle size of 16 ± 5 nm, it was found that the synthesized ZnO NPs contain a hexagonal wurtzite structure. ZnO NPs have antibacterial activity against Gram-positive Staphylococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli). The antiproliferative activity of ZnO NPs was tested against the human colon cancer cell line and mouse normal fibroblast cell line using MTT assay in vitro. The results show that the prepared nanoparticles had antiproliferative in screened incubation time and concentrations.

Abstract

Nanotechnology has recently emerged as an essential field of study in modern materials science. The green synthesis of nanoparticles using plant extracts is of great interest because it is cost-effective, eco-friendly, and suitable for large-scale production. The study highlights the synthesis of ZnO nanoparticles (ZnO NPs) using Laurus nobilis (L. nobilis) leaf extract and their characterization and biological activities for potential applications in the biomedical field. ZnO NPs were synthesized using Laurus nobilis leaf extract. The synthesized ZnO NPs were characterized by UV-Vis spectroscopy, TEM, XRD, and FT-IR. According to TEM and XRD diffraction analysis, with a mean particle size of 16 ± 5 nm, it was found that the synthesized ZnO NPs contain a hexagonal wurtzite structure. ZnO NPs have antibacterial activity against Gram-positive Staphylococcus aureus (S. aureus) and Gram-negative Escherichia coli (E. coli). The antiproliferative activity of ZnO NPs was tested against the human colon cancer cell line and mouse normal fibroblast cell line using MTT assay in vitro. The results show that the prepared nanoparticles had antiproliferative in screened incubation time and concentrations.

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Bu Makaleye Atıf Yap

Sivri, F. M., Önem, E., Akkoç, S., Çırrık, C., Ezer, A. (2023). Biosynthesis of ZnO nanoparticles using Laurus nobilis leaf extract and investigation of antiproliferative and antibacterial activity potential. International Journal of Secondary Metabolite, Volume: 10 Issue: 3. https://doi.org/10.21448/ijsm.1266244

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