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Dergiler / International Journal of Secondary Metabolite / 2026 / Volume: 13 Issue: 1

Influence of time of harvesting on phytochemical composition and antioxidant activity of different organs of Dittrichia viscosa (L.) Greuter

Ercan Petekkaya(Istanbul Medipol University, Graduate School of Health Sciences)0009-0002-9784-7277
Tuğba İduğ(ISTANBUL MEDIPOL UNIVERSITY)0000-0001-8241-647X
Sayfa
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Yayın Tarihi
2026-03-09
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Total phenolic and flavonoid contents and antioxidant activity of extracts obtained from leaves, roots, and flowers provide evidence for the reliability of their traditional use.

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Amaç & Hipotez:Traditionally, the leaves and roots of Dittrichia viscosa are used as natural remedies for ailments, serving externally as an antispasmodic, sedative, and antiseptic, for treating wound healing, women's infertility, bronchial disorders, and hemorrhoids.
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Temel Bulgular & Veri:According to the results, the highest amount of phenolic and flavonoid content values was found in July harvest leaves (L07).
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Sonuç & Katkı:Total phenolic and flavonoid contents and antioxidant activity of extracts obtained from leaves, roots, and flowers provide evidence for the reliability of their traditional use.
🔬Tür:Research Article
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Dittrichia viscosa · Antioxidant activity · DPPH

Özet

Traditionally, the leaves and roots of Dittrichia viscosa are used as natural remedies for ailments, serving externally as an antispasmodic, sedative, and antiseptic, for treating wound healing, women's infertility, bronchial disorders, and hemorrhoids. It also exhibits various pharmacological properties, including antioxidant, enzyme inhibition, antibacterial, and anticancer activities. There has been limited comparison research on the ideal harvest time and plant part to extract for human health. This study aims to evaluate in which harvest period, and which part of the plant is rich in phenolic and flavonoid compounds throughout the year. Total phenolic and flavonoid content were quantified, and the DPPH radical scavenging activity test was performed on the methanol extracts. According to the results, the highest amount of phenolic and flavonoid content values was found in July harvest leaves (L07). This extract was analyzed with LC-MS/MS. The results were as follows: quercetin 40.66 mg/kg, rutin 16.41 mg/kg, rosmarinic acid 17.84 mg/kg, caffeic acid 7.98 mg/kg, and chlorogenic acid 3.89 mg/kg. Total phenolic and flavonoid contents and antioxidant activity of extracts obtained from leaves, roots, and flowers provide evidence for the reliability of their traditional use.

Abstract

Traditionally, the leaves and roots of Dittrichia viscosa are used as natural remedies for ailments, serving externally as an antispasmodic, sedative, and antiseptic, for treating wound healing, women's infertility, bronchial disorders, and hemorrhoids. It also exhibits various pharmacological properties, including antioxidant, enzyme inhibition, antibacterial, and anticancer activities. There has been limited comparison research on the ideal harvest time and plant part to extract for human health. This study aims to evaluate in which harvest period, and which part of the plant is rich in phenolic and flavonoid compounds throughout the year. Total phenolic and flavonoid content were quantified, and the DPPH radical scavenging activity test was performed on the methanol extracts. According to the results, the highest amount of phenolic and flavonoid content values was found in July harvest leaves (L07). This extract was analyzed with LC-MS/MS. The results were as follows: quercetin 40.66 mg/kg, rutin 16.41 mg/kg, rosmarinic acid 17.84 mg/kg, caffeic acid 7.98 mg/kg, and chlorogenic acid 3.89 mg/kg. Total phenolic and flavonoid contents and antioxidant activity of extracts obtained from leaves, roots, and flowers provide evidence for the reliability of their traditional use.

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Bu Makaleye Atıf Yap

Petekkaya, E., İduğ, T. (2026). Influence of time of harvesting on phytochemical composition and antioxidant activity of different organs of Dittrichia viscosa (L.) Greuter. International Journal of Secondary Metabolite, Volume: 13 Issue: 1. https://doi.org/10.21448/ijsm.1677653

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