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Dergiler / Çukurova Anestezi ve Cerrahi Bilimler Dergisi / 2026 / Cilt: 7 Sayı: 3

Comparison of De Ritis Rate for Del Nido Versus Blood Cardioplegia in Patients Who Underwent Coronary Artery Bypass Graft Under Cardiopulmonary Bypass

Bişar Amaç(HARRAN UNIVERSITY, FACULTY OF HEALTH SCIENCES)0000-0003-0320-4239
Murat Ziya Bağış(HARRAN UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF CARDIOVASCULAR SURGERY)0000-0002-4088-7510
Mahmut Padak(HARRAN UNIVERSITY, FACULTY OF HEALTH SCIENCES)0000-0001-6863-1907
Sayfa
144–148
Yayın Tarihi
2024-09-30
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Conclusion: The Del Nido cardioplegia solution may be superior to blood cardioplegia in CABG cases accompanied by CPB regarding the De Ritis ratio.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Aim: Within the scope of this research, we aimed to compare the liver function tests, liver enzymes and De Ritis ratio (AST/ALT) of patients given Del Nido cardioplegia and blood cardioplegia in coronary heart surgery.
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Temel Bulgular & Veri:Methods: This retrospective study included a total of 80 patients who underwent CPB-guided coronary heart surgery (CABG) with 40 Del Nido cardioplegia solutions and 40 blood cardioplegia solutions.
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Sonuç & Katkı:Conclusion: The Del Nido cardioplegia solution may be superior to blood cardioplegia in CABG cases accompanied by CPB regarding the De Ritis ratio.
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Cardiopulmonary bypass · coronary artery bypass graft · del nido cardioplegia

Abstract

Aim: Within the scope of this research, we aimed to compare the liver function tests, liver enzymes and De Ritis ratio (AST/ALT) of patients given Del Nido cardioplegia and blood cardioplegia in coronary heart surgery. Methods: This retrospective study included a total of 80 patients who underwent CPB-guided coronary heart surgery (CABG) with 40 Del Nido cardioplegia solutions and 40 blood cardioplegia solutions. CPB-guided coronary heart surgery patients given Del Nido cardioplegia solution were determined as the first group (Group 1), and patients given blood cardioplegia were determined as the second group (Group 2). Results: Preoperative and postoperative aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin, direct bilirubin, and gamma-glutamyl transferase (GGT) levels of the groups were similar (p<0.005). AST, ALT, total bilirubin, direct bilirubin, and GGT levels were similar in CPB output (p<0.005). The De Ritis ratio of the groups was similar on the preoperative and postoperative 1st day (p=0.072; p=0.687, respectively), and the rate of ritis at CPB output was higher in group 2 (p=0.003). The requirement for defibrillation was higher in group 1 (p=0.044). Conclusion: The Del Nido cardioplegia solution may be superior to blood cardioplegia in CABG cases accompanied by CPB regarding the De Ritis ratio.

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Bu Makaleye Atıf Yap

Amaç, B., Bağış, M. Z., Padak, M. (2024). Comparison of De Ritis Rate for Del Nido Versus Blood Cardioplegia in Patients Who Underwent Coronary Artery Bypass Graft Under Cardiopulmonary Bypass. Çukurova Anestezi ve Cerrahi Bilimler Dergisi, Cilt: 7 Sayı: 3, 144–148. https://doi.org/10.36516/jocass.1513739

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