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Dergiler / Ankara Üniversitesi Veteriner Fakültesi Dergisi / 2018 / Volume: 65 Issue: 4

Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases)

Enver Beytut
Engin Kılıç
Sadık Yayla
Sayfa
—
Yayın Tarihi
2018-11-09
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Nevertheless, neoplasms originating from melanocytes always need advanced imaging techniques along with histopathological and immunohistochemical examination while assessing biological behavior of the tumour.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Three male calves with a dark mass, hanging down on the skin at various parts of the body, were presented for clinical examination.
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Temel Bulgular & Veri:All masses were present at the birth of the calves and their size increased with time.
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Sonuç & Katkı:Nevertheless, neoplasms originating from melanocytes always need advanced imaging techniques along with histopathological and immunohistochemical examination while assessing biological behavior of the tumour.
🔬Tür:Short Communication
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Calves · congenital cutaneous melanoma · histopathology

Abstract

Three male calves with a dark mass, hanging down on the skin at various parts of the body, were presented for clinical examination. All masses were present at the birth of the calves and their size increased with time. The masses were extirpated by a routine surgical operation and presented for histopathological examination. Tumour cells having cytoplasmic melanin granules showed a round or spindle-shaped nuclei. The mean mitotic rate was 5-7 at a high power field. Neoplastic melanocytes displayed an evident cytoplasmic immunolabeling to Melan A, HMB-45, S-100, NSE, and Vimentin. Tumour cells showed a nuclear positivity for Ki-67. Nuclear pleomorphism and a high mitotic rate along with the positive reaction of neoplastic cells to the melanocytic markers were indicative of melanoma. Nevertheless, neoplasms originating from melanocytes always need advanced imaging techniques along with histopathological and immunohistochemical examination while assessing biological behavior of the tumour.

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Bu Makaleye Atıf Yap

Beytut, E., Kılıç, E., Yayla, S. (2018). Histopathological and immunohistochemical evaluation of congenital cutaneous melanomas in calves (3 cases). Ankara Üniversitesi Veteriner Fakültesi Dergisi, Volume: 65 Issue: 4. https://doi.org/10.1501/Vetfak_0000002877

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