The effects of calcitonin on hepatic glutathione and lipid peroxidation must be further evaluated.
📌 3 Maddede Bu Makale
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Amaç & Hipotez:It has been reported that cold-restraint stress significantly decreases hepatic and gastric glutathione and increases lipid peroxidation levels.
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Temel Bulgular & Veri:Calcitonin pretreatment did not significantly influence the gastric glutathione and lipid peroxidation levels but significantly increased the hepatic glutathione and lipid peroxidation levels.
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Sonuç & Katkı:The effects of calcitonin on hepatic glutathione and lipid peroxidation must be further evaluated.
It has been reported that cold-restraint stress significantly decreases hepatic and gastric glutathione and increases lipid peroxidation levels. In the present study, the effect of calcitonin on gastric and hepatic glutathione and lipid peroxidation levels after cold-restraint stress exposure was investigated in rats. Calcitonin pretreatment did not significantly influence the gastric glutathione and lipid peroxidation levels but significantly increased the hepatic glutathione and lipid peroxidation levels. Our results suggest that the anti-ulcerogenic effect of calcitonin is not related to changes in the gastric lipid peroxidation and glutathion levels. The effects of calcitonin on hepatic glutathione and lipid peroxidation must be further evaluated.
Erin, N., Atınç, N., Özkutlu, U., Yalçın, S., Oktay, Ş. (1993). The effects of calcitonin on stress-induced gastric ulcers, glutathione and lipid peroxidation in rats. Marmara Medical Journal, Volume: 6 Issue: 3. https://ajindex.com/articles/1287645
Tache Y. Garrick T, Rayboult H. Central nervous system action of peptides to Influence gastrointestinal motor functions. Qastroenterology 1990; 98:517-528.