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Dergiler / Marine Science and Technology Bulletin / 2026 / Volume: 15 Issue: 3

Glucosamine: Production and applications

Ali Eslem Kadak(Kastamonu University, Devrekani TOBB Vocational School, Department of Veterinary Medicine, 37700, Kastamonu, Türkiye)0000-0002-7128-9134
Aygül Küçükgülmez(Cukurova University, Faculty of Fisheries, Department of Seafood Processing Technology, 01330, Adana, Türkiye)0000-0001-5419-5921
Mehmet Çelik(Cukurova University, Faculty of Ceyhan Veterinary Medicine, Department of Food Hygiene and Technology, 01330, Adana, Türkiye)0000-0003-4330-2490
Claudia Plinz(Europa-Universität Flensburg, Institute for Social Studies, 24943, Flensburg, Germany)0009-0008-3648-9721
Sayfa
—
Yayın Tarihi
2026-09-30
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Yapay Zeka Hızlı Bakış & Çıkarımlar

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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

Furthermore, while generally recognized as a safe dietary supplement by the USFDA, clinical application must account for potential allergenic reactions in individuals with shellfish sensitivities and monitor long-term toxicological profiles to ensure patient safety.

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Glucosamine, an essential amino monosaccharide derived from chitinous biomass, serves as a primary substrate for the synthesis of glycosaminoglycan chains in human cartilage.
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Temel Bulgular & Veri:Despite its $3.5 billion global market value, industrial production faces significant feasibility challenges, including the high cost of enzymatic processes and the environmental impact of chemical deacetylation waste.
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Sonuç & Katkı:Furthermore, while generally recognized as a safe dietary supplement by the USFDA, clinical application must account for potential allergenic reactions in individuals with shellfish sensitivities and monitor long-term toxicological profiles to ensure patient safety.
🔬Tür:Literatür & Derleme Çalışması
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Shellfish wastes · Glucosamine extraction · Osteoarthritis

Abstract

Glucosamine, an essential amino monosaccharide derived from chitinous biomass, serves as a primary substrate for the synthesis of glycosaminoglycan chains in human cartilage. While naturally occurring in the body, its commercial production primarily involves the chemical or enzymatic degradation of shellfish waste. This review evaluates the efficacy of its four prevalent forms; glucosamine, glucosamine hydrochloride, glucosamine sulphate, and N-acetyl glucosamine with a focus on their therapeutic mechanisms. Specifically, glucosamine derivatives manage osteoarthritis and rheumatoid arthritis by promoting cartilage repair and exerting potent anti-inflammatory effects, while also showing promise in treating cardiovascular, neurological, and dermatological conditions. Despite its $3.5 billion global market value, industrial production faces significant feasibility challenges, including the high cost of enzymatic processes and the environmental impact of chemical deacetylation waste. Furthermore, while generally recognized as a safe dietary supplement by the USFDA, clinical application must account for potential allergenic reactions in individuals with shellfish sensitivities and monitor long-term toxicological profiles to ensure patient safety.

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Bu Makaleye Atıf Yap

Kadak, A. E., Küçükgülmez, A., Çelik, M., Plinz, C. (2026). Glucosamine: Production and applications. Marine Science and Technology Bulletin, Volume: 15 Issue: 3. https://doi.org/10.33714/masteb.1907073

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