Dergiler / Bakırköy Tıp Dergisi / 2018 / Cilt: 14 - Sayı: 1

Mean Platelet Volume as a Predictive Marker for Inflammatory Reactivation after Total Hip Arthroplasty

Total kalça artroplastisi sonrası inflamatuar reaktivasyonun bir belirteçi olarak ortalama trombosit hacmi

Sayfa
57–62
DOI
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⚡ TL;DR(1 Cümlede Hızlı Çıkarım)

The serum MPV values obtained in our study may guide future studies investigating inflammatory reactivation in hip arthroplasty surgeries

📌 3 Maddede Bu Makale

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Amaç & Hipotez:Objectives: Mean platelet volume (MPV) is assosiated with platelet function and activation.
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Temel Bulgular & Veri:Increased MPV values indicate elevated platelet functions and are assosiated with inflammation.
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Sonuç & Katkı:The serum MPV values obtained in our study may guide future studies investigating inflammatory reactivation in hip arthroplasty surgeries
🔬Tür:Araştırma Makalesi
📍Kapsam:Genişletilmiş Akademik Örneklem
⚙️Değişkenler:Alan Parametreleri

Özet

Objectives: Mean platelet volume (MPV) is assosiated with platelet function and activation. Increased MPV values indicate elevated platelet functions and are assosiated with inflammation. We investigated postoperative MPV changes of the patients with osteoarthritis (OA) after total hip arthroplasty. Material and Method: This retrospective study was conducted on 813 patients with coxarthrosis and 152 patients without primary coxarthrosis (control group). The patients were divided into two groups. The first group was treated with total hip arthroplasty (n=312) and the second with conservative methods (n=501). MPV, ESR, and CRP were eveluated. Early phase (up to 10 days after the operation), and late phase (>30 days postoperation) data of the patients with total hip arthroplasty were recorded. Results: Statisticaly significant differences on the mean MPV values were found between control and conservative treatment groups, and also between control and early phase surgical treatment groups (p=0.001 and p=0.005, respectively). No statistically significant difference was determined between control and late phase surgical treatment groups (p=0.796). Statisticaly significant differences were determined in the mean MPV values between conservative treatment and late phase surgical treatment groups (p=0.001), but no statistically significant difference was determined between conservative treatment and late phase surgical treatment groups (p=0.057). Conclusion: We think that changes in serum MPV values can be used as a predictive marker for inflammatory reactivation following total hip replacement surgery. The serum MPV values obtained in our study may guide future studies investigating inflammatory reactivation in hip arthroplasty surgeries

Abstract

Amaç: Ortalama trombosit hacmi (MPV) trombosit fonksiyonu ve aktivasyonu ile ilişkilidir. Artan MPV değerleri, trombosit fonksiyonlarının yükseldiğini ve inflamasyonu ile birlikteliği göstermektedir. Total kalça artroplastisi sonrası osteoartritli (OA) hastaların postoperatif MPV değişikliklerini araştırdık. Gereç ve Yöntem: Bu retrospektif çalışma, koksartrozlu 813 hasta ve primer koksartrozu olmayan 152 hasta üzerinde yapıldı (kontrol grubu). Hastalar iki gruba ayrıldı. Birinci grup total kalça artroplastisi (n=312) ve ikinci grup konservatif yöntemlerle (n=501) tedavi edildi. MPV, ESR ve CRP değerlendirildi. Total kalça artroplastisi uygulanan hastaların erken evre (operasyondan sonra 10 güne kadar) ve geç evre (operasyondan 30 gün sonrası) verileri kaydedildi. Bulgular: Kontrol grubu ile konservatif tedavi grubu arasında ve kontrol grubu ile erken evre cerrahi tedavi grubu arasında istatistiksel olarak anlamlı ortalama MPV değerleri bulundu (sırasıyla p=0.001 ve p=0.005). Kontrol grubu ile geç evre cerrahi tedavi grubu arasında istatistiksel olarak anlamlı fark bulunmadı (p=0.796). Konservatif tedavi grubu ile geç evre cerrahi tedavi grubu arasında ortalama MPV değerleri istatistiksel olarak anlamlı bulundu (p=0.001), ancak konservatif tedavi grubu ile geç evre cerrahi tedavi grubu arasında istatistiksel olarak anlamlı fark yoktu (p=0.057). Sonuç: Total kalça protezi ameliyatı sonrası inflamatuar reaktivasyou belirlemeye yönelik yeni çalışmalarda belirlediğimiz MPV değerlerindeki değişikliklerin katkı sağlayacağını düşünüyoruz

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Bu Makaleye Atıf Yap

BALIK, M. S., ERKUT, A., GÜVERCİN, Y., KESKİN, D. (2018). Mean Platelet Volume as a Predictive Marker for Inflammatory Reactivation after Total Hip Arthroplasty. Bakırköy Tıp Dergisi, Cilt: 14 - Sayı: 1, 57–62. https://ajindex.com/articles/127526

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Kaynakça (4)

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